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Reaction-diffusion systems have been widely used to study spatio-temporal phenomena in cell biology, such as cell polarization. Coupled bulk-surface models naturally include compartmentalization of cytosolic and membrane-bound polarity…

斑图形成与孤子 · 物理学 2020-08-11 Frédéric Paquin-Lefebvre , Bin Xu , Kelsey L. DiPietro , Alan E. Lindsay , Alexandra Jilkine

Mass-conserving reaction-diffusion systems with bistable nonlinearity are useful models for studying cell polarity formation, which is a key process in cell division and differentiation. We rigorously show the existence and stability of…

偏微分方程分析 · 数学 2025-05-23 Masataka Kuwamura , Takashi Teramoto , Hideo Ikeda

Patterns in reaction-diffusion systems often contain two spatial scales; a long scale determined by a typical wavelength or domain size, and a short scale pertaining to front structures separating different domains. Such patterns naturally…

patt-sol · 物理学 2009-10-22 Aric Hagberg , Ehud Meron

Cellular differentiation in a developping organism is studied via a discrete bistable reaction-diffusion model. A system of undifferentiated cells is allowed to receive an inductive signal emenating from its environment. Depending on the…

斑图形成与孤子 · 物理学 2009-11-10 Gabor Fath , Zbigniew Domanski

A reaction-diffusion system with mass conservation modelling cell polarity is considered. A range of the parameters is found where the solution converges exponentially to the constant equilibrium and the $\omega$-limit set of the solution…

偏微分方程分析 · 数学 2021-04-21 Evangelos Latos , Takashi Suzuki

Signaling molecules play an important role for many cellular functions. We investigate here a general system of two membrane reaction-diffusion equations coupled to a diffusion equation inside the cell by a Robin-type boundary condition and…

偏微分方程分析 · 数学 2015-06-16 Andreas Rätz , Matthias Röger

We study global-in-time behavior of the solution to a reaction-diffusion system with mass conservation, as proposed in the study of cell polarity, particularly, the second model of \cite{oi07}. First, we show global-in-time existence of…

偏微分方程分析 · 数学 2015-11-13 Evangelos Latos , Yoshihisa Morita , Takashi Suzuki

Oscillatory Zoning (OZ) is a phenomenon exhibited by many geologically formed crystals. It is characterized by quasi periodic oscillations in the composition of a solid solution, caused by self-organization. We present a new model for OZ.…

材料科学 · 物理学 2009-11-11 Felix Kalischewski , Ihor Lubashevsky , Andreas Heuer

We study dynamics emergent from a two-dimensional reaction--diffusion process modelled via a finite lattice dynamical system, as well as an analogous PDE system, involving spatially nonlocal interactions. These models govern the evolution…

组织与器官 · 定量生物学 2018-11-14 Andrew L. Krause , Dmitry Beliaev , Robert A. Van Gorder , Sarah L. Waters

Protein pattern formation is essential for the spatial organization of many intracellular processes like cell division, flagellum positioning, and chemotaxis. A prominent example of intracellular patterns are the oscillatory pole-to-pole…

生物物理 · 物理学 2018-02-21 Erwin Frey , Jacob Halatek , Simon Kretschmer , Petra Schwille

Motile eukaryotic cells display distinct modes of migration that often occur within the same cell type. It remains unclear, however, whether transitions between the migratory modes require changes in external conditions, or whether the…

斑图形成与孤子 · 物理学 2025-05-29 Jack M. Hughes , Cristina Martinez-Torres , Carsten Beta , Leah Edelstein-Keshet , Arik Yochelis

Demixing of binary fluids subjected to slow temperature ramps shows repeated waves of nucleation which arise as a consequence of the competition between generation of supersaturation by the temperature ramp and relaxation of supersaturation…

统计力学 · 物理学 2012-10-16 Izabella J. Benczik , Jürgen Vollmer

Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…

动力系统 · 数学 2022-08-12 Shuang Liu , Li-Tien Cheng , Bo Li

Spatiotemporal patterns are common in biological systems. For electrically-coupled cells previous studies of pattern formation have mainly used external forcing as the main bifurcation parameter. The purpose of this paper is to show that…

动力系统 · 数学 2021-11-02 H. O. Fatoyinbo , R. G. Brown , D. J. W. Simpson , B. van Brunt

Dispersion curves to a oscillatory reaction-diffusion system with the self-consistent flow have obtained by means of numerical calculations. The flow modulates the shape of dispersion curves and characteristics of traveling waves. The point…

patt-sol · 物理学 2007-05-23 Hiroyasu Yamada , Toshiyuki Nakagaki

The motion of a eukaryotic cell presents a variety of interesting and challenging problems from both a modeling and a computational perspective. The processes span many spatial scales (from molecular to tissue) as well as disparate time…

细胞行为 · 定量生物学 2010-11-25 Ben Vanderlei , James J. Feng , Leah Edelstein-Keshet

Various molecules exclusively accumulate at the front or back of migrating eukaryotic cells in response to a shallow gradient of extracellular signals. Directional sensing and signal amplification highlight the essential properties in the…

细胞行为 · 定量生物学 2015-06-26 Mikiya Otsuji , Shuji Ishihara , Carl Co , Kozo Kaibuchi , Atsushi Mochizuki , Shinya Kuroda

Basic problems for the construction of a scenario for the Life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra-inter dynamics is presented. It consists of internal dynamics of a unit, interaction…

adap-org · 物理学 2015-06-24 Kunihiko Kaneko

In this work we investigate the process of pattern formation in a two dimensional domain for a reaction-diffusion system with nonlinear diffusion terms and the competitive Lotka-Volterra kinetics. The linear stability analysis shows that…

斑图形成与孤子 · 物理学 2014-03-03 G. Gambino , M. C. Lombardo , M. Sammartino

Cell polarization is a critical process that separates molecular species into two distinct regions in prokaryotic and eukaryotic cells, guiding biological processes such as cell division and cell differentiation. Although several underlying…

分子网络 · 定量生物学 2025-01-28 Yixuan Chen , Guoye Guan , Lei-Han Tang , Chao Tang
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