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Mediation analysis aims to separate the indirect effect through mediators from the direct effect of the exposure on the outcome. It is challenging to perform mediation analysis with neuroimaging data which involves high dimensionality,…

统计方法学 · 统计学 2025-12-30 Yuliang Xu , Timothy D Johnson , Mary Heitzeg , Jian Kang

Functional near-infrared spectroscopy (fNIRS) is a non-invasive, low-cost method used to study the brain's blood flow pattern. Such patterns can enable us to classify performed by a subject. In recent research, most classification systems…

机器学习 · 计算机科学 2021-01-18 Sajila D. Wickramaratne , MD Shaad Mahmud

Functional neuroimaging measures how the brain responds to complex stimuli. However, sample sizes are modest, noise is substantial, and stimuli are high dimensional. Hence, direct estimates are inherently imprecise and call for…

应用统计 · 统计学 2016-02-05 Leila Wehbe , Aaditya Ramdas , Rebecca C. Steorts , Cosma Rohilla Shalizi

Fetal functional Magnetic Resonance Imaging (fMRI) has emerged as a powerful tool for investigating brain development in utero, holding promise for generating developmental disease biomarkers and supporting prenatal diagnosis. However, to…

Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of \emph{gradual and continuous} changes in the brain blood oxygenated…

神经元与认知 · 定量生物学 2011-07-25 Enzo Tagliazucchi , Pablo Balenzuela , Daniel Fraiman , Dante R. Chialvo

Graphical models, used to express conditional dependence between random variables observed at various nodes, are used extensively in many fields such as genetics, neuroscience, and social network analysis. While most current statistical…

统计方法学 · 统计学 2022-10-25 Jiajing Niu , Boyoung Hur , John Absher , D. Andrew Brown

Currently there is no validated objective measure of pain. Recent neuroimaging studies have explored the feasibility of using functional near-infrared spectroscopy (fNIRS) to measure alterations in brain function in evoked and ongoing pain.…

机器学习 · 计算机科学 2018-08-22 Daniel Lopez-Martinez , Ke Peng , Sarah C. Steele , Arielle J. Lee , David Borsook , Rosalind Picard

The goals of functional Magnetic Resonance Imaging (fMRI) include high spatial and temporal resolutions with a high signal-to-noise ratio (SNR). To simultaneously improve spatial and temporal resolutions and maintain the high SNR advantage…

图像与视频处理 · 电气工程与系统科学 2024-07-10 Shouchang Guo

Accurate segmentation of brain tissue in magnetic resonance images (MRI) is a diffcult task due to different types of brain abnormalities. Using information and features from multimodal MRI including T1, T1-weighted inversion recovery…

计算机视觉与模式识别 · 计算机科学 2019-03-07 Yongpei Zhu , Zicong Zhou , Guojun Liao , Qianxi Yang , Kehong Yuan

The universal tendency in scanning probe microscopy (SPM) over the last two decades is to transition from simple 2D imaging to complex detection and spectroscopic imaging modes. The emergence of complex SPM engines brings forth the…

Resting state fMRI is an imaging modality which reveals brain activity localization through signal changes, in what is known as Resting State Networks (RSNs). This technique is gaining popularity in neurosurgical pre-planning to visualize…

机器学习 · 计算机科学 2022-09-22 Sejal Ghate , Alberto Santamaria-Pang , Ivan Tarapov , Haris I Sair , Craig K Jones

Major depressive disorder (MDD) requires study of brain functional connectivity alterations for patients, which can be uncovered by resting-state functional magnetic resonance imaging (rs-fMRI) data. We consider the problem of identifying…

机器学习 · 统计学 2022-06-10 Shuai Liu , Yixuan Qiu , Baojuan Li , Huaning Wang , Xiangyu Chang

Functional magnetic resonance imaging (fMRI) provides an indirect measurement of neuronal activity via hemodynamic responses that vary across brain regions and individuals. Ignoring this hemodynamic variability can bias downstream…

图像与视频处理 · 电气工程与系统科学 2026-01-26 William Consagra , Eardi Lila

In neuroimaging studies, it becomes increasingly important to study associations between different imaging modalities using image-on-image regression (IIR), which faces challenges in interpretation, statistical inference, and prediction.…

应用统计 · 统计学 2026-03-24 Guoxuan Ma , Bangyao Zhao , Hasan Abu-Amara , Jian Kang

Functional magnetic resonance imaging (fMRI) based image reconstruction plays a pivotal role in decoding human perception, with applications in neuroscience and brain-computer interfaces. While recent advancements in deep learning and…

计算机视觉与模式识别 · 计算机科学 2025-02-25 Weiyu Guo , Guoying Sun , JianXiang He , Tong Shao , Shaoguang Wang , Ziyang Chen , Meisheng Hong , Ying Sun , Hui Xiong

Functional magnetic resonance imaging (fMRI) is a non-invasive and in-vivo imaging technique essential for measuring brain activity. Functional connectivity is used to study associations between brain regions, either while study subjects…

应用统计 · 统计学 2024-03-26 Kun Meng , Ani Eloyan

Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…

Scaling temporal dynamics in functional MRI (fMRI) signals have been evidenced for a decade as intrinsic characteristics of ongoing brain activity (Zarahn et al., 1997). Recently, scaling properties were shown to fluctuate across brain…

统计理论 · 数学 2013-08-21 P. Ciuciu , G. Varoquaux , P. Abry , S. Sadaghiani , A. Kleinschmidt

Functional MRI (fMRI) is widely used to examine brain functionality by detecting alteration in oxygenated blood flow that arises with brain activity. This work aims to investigate the neurological variation of human brain responses during…

计算机视觉与模式识别 · 计算机科学 2023-09-28 Naveen Kanigiri , Manohar Suggula , Debanjali Bhattacharya , Neelam Sinha

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

神经元与认知 · 定量生物学 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu