中文
相关论文

相关论文: Low Stress Ion Conductance Microscopy of Sub-Cellu…

200 篇论文

Mechanical properties of a nanomechanical resonator have a significant impact on the performance of a resonant Nano-electromechanical system (NEMS) device. Here we study the mechanical properties of suspended membranes fabricated out of…

应用物理 · 物理学 2019-07-09 S. S. Jugade , A. Aggarwal , A. K. Naik

We use a cooled Scanning Probe Microscope (SPM) to electron motion in nanoscale devices. The charged tip of the SPM is raster scanned at a constant height above the surface as the conductance of the device is measured. The image charge…

介观与纳米尺度物理 · 物理学 2017-03-08 Sagar Bhandari , Gil-Ho Lee , Philip Kim , Robert M. Westervelt

Accurate assessment of stiffness distribution is essential due to the critical role of single cell mechanobiology in the regulation of many vital cellular processes such as proliferation, adhesion, migration, and motility. Cell stiffness is…

In this work we explore mechanical properties of graphene samples of variable thickness. For this purpose, we coupled a high pressure sapphire anvil cell to a micro-Raman spectrometer. From the evolution of the G band frequency with stress…

Detecting elevated intracranial pressure (ICP) is crucial in diagnosing and managing various neurological conditions. These fluctuations in pressure are transmitted to the optic nerve sheath (ONS), resulting in changes to its diameter,…

The effect of surface stress on the stiffness of cantilever beams remains an outstanding problem in the physical sciences. While numerous experimental studies report significant stiffness change due to surface stress, theoretical…

介观与纳米尺度物理 · 物理学 2012-11-05 Rassul B. Karabalin , L. G. Villanueva , M. H. Matheny , John E. Sader , Michael L. Roukes

We investigate the properties of membranes under tension by Monte-Carlo simulations of a generic coarse-grained model for lipid bilayers. We give a comprising overview of the behavior of several membrane characteristics, such as the area…

生物物理 · 物理学 2010-03-17 Jörg Neder , Beate West , Peter Nielaba , Friederike Schmid

Laser-driven plasma wakefields can provide hundreds of MeV electron beam in mm-range distances potentially shrinking the dimension of the actual particle accelerators. The plasma density plays a fundamental role in the control and stability…

The activity of cell membrane inclusions (such as ion channels) is influenced by the host lipid membrane, to which they are elastically coupled. This coupling concerns the hydrophobic thickness of the bilayer (imposed by the length of the…

软凝聚态物质 · 物理学 2018-06-24 Florent Bories , Doru Constantin , Paolo Galatola , Jean-Baptiste Fournier

Microfluidics offer remarkable flexibility for in-flow analyte characterization and can even measure the mechanical properties of biological cells through the application of hydrodynamic forces. In this work, we present a new approach to…

软凝聚态物质 · 物理学 2025-01-22 Alberto Martin-Perez , Daniel Ramos

Resistive Pulse Sensing (RPS) is a key label-free technology to measure particles and single-cell size distribution. As a growing corpus of evidence supports that cancer cells exhibit distinct mechanical phenotypes from healthy cells,…

生物物理 · 物理学 2020-04-01 Antoine Riaud , Anh L. P. Thai , Wei Wang , Valerie Taly

The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

The internal structure of the Fin-Ray fingers plays a significant role in their adaptability and grasping performance. However, modeling the grasp force and deformation behavior for design purposes is challenging. When the Fin-Ray finger…

机器人学 · 计算机科学 2026-02-17 Ali Ghanizadeh , Ali Ahmadi , Arash Bahrami

We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation, the membrane bends at the point of…

软凝聚态物质 · 物理学 2011-08-26 Chen-Hsi Huang , Pai-Yi Hsiao , Fan-Gang Tseng , Shih-Kang Fan , Chien-Chung Fu , Rong-Long Pan

Understanding mechanosensitivity, i.e. how cells sense the stiffness of their environment is very important, yet there is a fundamental difficulty in understanding its mechanism: to measure an elastic modulus one requires two points of…

细胞行为 · 定量生物学 2015-06-17 Matteo Escude , Michelle K. Rigozzi , Eugene M. Terentjev

We perform a theoretical investigation of the clamped laser intensity inside the filament plasma as a function of gas pressure with external focusing. Unlike the clamped intensity under the selffocusing condition, which is independent on…

等离子体物理 · 物理学 2022-05-17 Quanjun Wang , Yuxuan Zhang , Yue Zheng , Zhoumingyang Zhu , Pengji Ding , Zuoye Liu , Bitao Hu

To better understand lipid membranes in living organisms, the study of intermolecular forces using the osmotic pressure technique applied to model lipid membranes has constituted the ground knowledge in the field of biophysics since four…

软凝聚态物质 · 物理学 2020-02-26 Niki Baccile , Viviana Cristiglio

A high sensitivity force sensor based on dielectric microspheres in vacuum, optically trapped by a single, upward-propagating laser beam, is described. Off-axis parabolic mirrors are used both to focus the 1064~nm trapping beam and to…

仪器与探测器 · 物理学 2020-09-10 Akio Kawasaki , Alexander Fieguth , Nadav Priel , Charles P. Blakemore , Denzal Martin , Giorgio Gratta

Both animal and plant tissue exhibit a nonlinear rheological phenomenon known as compression stiffening, or an increase in moduli with increasing uniaxial compressive strain. Does such a phenomenon exist in single cells, which are the…

The electron density close to the extraction grids and the co-extracted electrons represent a crucial issue when operating negative ion sources for fusion reactors. An excessive electron density in the plasma expansion region can indeed…

等离子体物理 · 物理学 2023-03-29 R. Agnello , R. Cavazzana , I. Furno , R. Jacquier , R. Pasqualotto , E. Sartori , G. Serianni