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相关论文: Causal Mediation Analysis with Hidden Confounders

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The incorporation of causal inference in mediation analysis has led to theoretical and methodological advancements -- effect definitions with causal interpretation, clarification of assumptions required for effect identification, and an…

统计方法学 · 统计学 2022-10-31 Trang Quynh Nguyen , Ian Schmid , Elizabeth A. Stuart

Mediation analysis is widely used for investigating direct and indirect causal pathways through which an effect arises. However, many mediation analysis studies are challenged by missingness in the mediator and outcome. In general, when the…

统计方法学 · 统计学 2023-09-25 Shuozhi Zuo , Debashis Ghosh , Peng Ding , Fan Yang

Causal mediation analysis seeks to investigate how the treatment effect of an exposure on outcomes is mediated through intermediate variables. Although many applications involve longitudinal data, the existing methods are not directly…

应用统计 · 统计学 2021-02-24 Shuxi Zeng , Stacy Rosenbaum , Elizabeth Archie , Susan Alberts , Fan Li

Observational studies are the primary source of data for causal inference, but it is challenging when existing unmeasured confounding. Missing data problems are also common in observational studies. How to obtain the causal effects from the…

统计方法学 · 统计学 2023-05-15 Renzhong Zheng

Recently, interest has grown in the use of proxy variables of unobserved confounding for inferring the causal effect in the presence of unmeasured confounders from observational data. One difficulty inhibiting the practical use is finding…

机器学习 · 计算机科学 2024-05-28 Feng Xie , Zhengming Chen , Shanshan Luo , Wang Miao , Ruichu Cai , Zhi Geng

In causal analysis, understanding the causal mechanisms through which an intervention or treatment affects an outcome is often of central interest. We propose a test to evaluate (i) whether the causal effect of a treatment that is randomly…

计量经济学 · 经济学 2026-03-05 Martin Huber , Kevin Kloiber , Lukáš Lafférs

The goal of causal mediation analysis, often described within the potential outcomes framework, is to decompose the effect of an exposure on an outcome of interest along different causal pathways. Using the assumption of sequential…

统计方法学 · 统计学 2021-11-09 Lexi Rene , Antonio R. Linero , Elizabeth Slate

Causal mediation analysis examines causal pathways linking exposures to disease. The estimation of interventional effects, which are mediation estimands that overcome certain identifiability problems of natural effects, has been advanced…

统计方法学 · 统计学 2025-04-23 Tong Chen , Stijn Vansteelandt , David Burgner , Toby Mansell , Margarita Moreno-Betancur

Causal mediation analysis is complicated with multiple effect definitions that require different sets of assumptions for identification. This paper provides a systematic explanation of such assumptions. We define five potential outcome…

统计方法学 · 统计学 2022-09-26 Trang Quynh Nguyen , Ian Schmid , Elizabeth L. Ogburn , Elizabeth A. Stuart

Causal decomposition has provided a powerful tool to analyze health disparity problems, by assessing the proportion of disparity caused by each mediator. However, most of these methods lack \emph{policy implications}, as they fail to…

统计方法学 · 统计学 2023-02-21 Xinwei Sun , Xiangyu Zheng , Jim Weinstein

Mediation analysis seeks to infer how much of the effect of an exposure on an outcome can be attributed to specific pathways via intermediate variables or mediators. This requires identification of so-called path-specific effects. These…

统计方法学 · 统计学 2019-06-06 Johan Steen , Stijn Vansteelandt

Causal mediation analysis is widely utilized to separate the causal effect of treatment into its direct effect on the outcome and its indirect effect through an intermediate variable (the mediator). In this study we introduce a functional…

应用统计 · 统计学 2018-05-21 Yi Zhao , Xi Luo , Martin Lindquist , Brian Caffo

Learning individual-level causal effects from observational data, such as inferring the most effective medication for a specific patient, is a problem of growing importance for policy makers. The most important aspect of inferring causal…

机器学习 · 统计学 2017-11-07 Christos Louizos , Uri Shalit , Joris Mooij , David Sontag , Richard Zemel , Max Welling

Causal indirect and direct effects provide an interpretable method for decomposing the total effect of an exposure on an outcome into the effect through a mediator and the effect through all other pathways. When the mediator is a biomarker,…

统计方法学 · 统计学 2021-08-02 Ariel Chernofsky , Ronald J. Bosch , Judith J. Lok

Causal mediation analysis has historically been limited in two important ways: (i) a focus has traditionally been placed on binary treatments and static interventions, and (ii) direct and indirect effect decompositions have been pursued…

统计方法学 · 统计学 2022-01-13 Nima S. Hejazi , Kara E. Rudolph , Mark J. van der Laan , Iván Díaz

Experiments often include multiple treatments, with the primary goal to compare the causal effects of those treatments. This study focuses on comparing the causal anatomies of multiple treatments through the use of causal mediation…

统计方法学 · 统计学 2019-07-03 Kirk Bansak

This research addresses the challenge of conducting interpretable causal inference between a binary treatment and its resulting outcome when not all confounders are known. Confounders are factors that have an influence on both the treatment…

机器学习 · 计算机科学 2023-10-24 Sohaib Kiani , Jared Barton , Jon Sushinsky , Lynda Heimbach , Bo Luo

Causal mediation analysis has been extended to estimate path-specific effects with multiple intermediate variables, isolating treatment effects through a mediator of interest while excluding pathways through its ancestors. Such analyses…

统计方法学 · 统计学 2026-05-12 Yang Bai , Sihan Wu , Baoluo Sun , Yifan Cui

Convenient access to observational data enables us to learn causal effects without randomized experiments. This research direction draws increasing attention in research areas such as economics, healthcare, and education. For example, we…

社会与信息网络 · 计算机科学 2019-12-03 Ruocheng Guo , Jundong Li , Huan Liu

Causal mediation analysis provides techniques for defining and estimating effects that may be endowed with mechanistic interpretations. With many scientific investigations seeking to address mechanistic questions, causal direct and indirect…