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In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

概率论 · 数学 2018-02-15 Carolina Fransson , Pieter Trapman

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

种群与进化 · 定量生物学 2020-06-09 Evangelos Magirou

There has been much recent interest in modelling epidemics on networks, particularly in the presence of substantial clustering. Here, we develop pairwise methods to answer questions that are often addressed using epidemic models, in…

种群与进化 · 定量生物学 2010-12-10 Thomas House , Matt J Keeling

Since COVID-19 was first identified in December 2019, various public health interventions have been implemented across the world. As different measures are implemented at different countries at different times, we conduct an assessment of…

计算机与社会 · 计算机科学 2020-05-15 Xiuyi Fan , Siyuan Liu , Jiarong Chen , Thomas C. Henderson

The novel Coronavirus (COVID-19) incidence in India is currently experiencing exponential rise but with apparent spatial variation in growth rate and doubling time rate. We classify the states into five clusters with low to the high-risk…

种群与进化 · 定量生物学 2020-07-14 Rabinder Kumar Prasad , Rosy Sarmah , Subrata Chakraborty

The development and authorization of COVID-19 vaccines has provided the clearest path forward to eliminate community spread hence end the ongoing SARS-CoV-2 pandemic. However, the limited pace at which the vaccine can be administered…

种群与进化 · 定量生物学 2021-03-11 Glenn Young , Pengcheng Xiao , Kenneth Newcomb , Edwin Michael

Pandemic control measures like lock-down, restrictions on restaurants and gatherings, social-distancing have shown to be effective in curtailing the spread of COVID-19. However, their sustained enforcement has negative economic effects. To…

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

种群与进化 · 定量生物学 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

Preventive care service delivery faces immense challenges when it comes to the level of coverage. Within this context, the case of child immunization is presented by applying operations management tools. This paper explores the application…

计算机与社会 · 计算机科学 2013-06-06 Mohammad Ishfaq , Faran Ahmad Qadri , Nadeem Javaid

This paper presents a practical global optimization algorithm for the K-center clustering problem, which aims to select K samples as the cluster centers to minimize the maximum within-cluster distance. This algorithm is based on a…

最优化与控制 · 数学 2026-03-04 Jiayang Ren , Ningning You , Kaixun Hua , Chaojie Ji , Yankai Cao

An accurate multiclass classification strategy is crucial to interpreting antibody tests. However, traditional methods based on confidence intervals or receiver operating characteristics lack clear extensions to settings with more than two…

定量方法 · 定量生物学 2024-05-07 Rayanne A. Luke , Anthony J. Kearsley , Paul N. Patrone

Efficient extraction of useful knowledge from these data is still a challenge, mainly when the data is distributed, heterogeneous and of different quality depending on its corresponding local infrastructure. To reduce the overhead cost,…

数据库 · 计算机科学 2017-04-17 Nhien-An Le-Khac , M-Tahar Kechadi

The COVID-19 pandemic highlighted significant challenges in the allocation of vital healthcare resources. Existing epidemiological models, specifically compartmental models, aimed to predict the spread of the COVID-19 virus and its impact…

物理与社会 · 物理学 2024-03-14 Hieu Bui , Sandra Eksioglu , Ruben Proano

Randomized controlled trials are often run in settings with many subpopulations that may have differential benefits from the treatment being evaluated. We consider the problem of sample selection, i.e., whom to enroll in a randomized trial,…

统计方法学 · 统计学 2024-06-26 Yuchen Hu , Henry Zhu , Emma Brunskill , Stefan Wager

In this paper, we explore the solvability and the optimal control problem for a compartmental model based on reaction-diffusion partial differential equations describing a transmissible disease. The nonlinear model takes into account the…

最优化与控制 · 数学 2023-08-25 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi

In this paper, an optimal resource allocation framework is proposed for the allocation of critical medical resources among different units during a pandemic. The framework is developed by considering the dynamics of Pandemic, hierarchical…

系统与控制 · 电气工程与系统科学 2022-03-14 Shuvrangshu Jana , Rudrashis Majumder , Debasish Ghose

The topic of finding effective strategy to halt virus in complex network is of current interest. We propose an immunization strategy for seasonal epidemics that occur periodically. Based on the local information of the infection status from…

应用统计 · 统计学 2015-06-22 Shu Yan , Shaoting Tang , Sen Pei , Shijin Jiang , Zhiming Zheng

With the increasing spread of COVID-19, it is important to systematically test more and more people. The current strategy for test-kit allocation is mostly rule-based, focusing on individuals having (a) symptoms for COVID-19, (b) travel…

人工智能 · 计算机科学 2020-04-07 Arpita Biswas , Shruthi Bannur , Prateek Jain , Srujana Merugu

Vaccination has been proven to be the most effective method to prevent infectious diseases. However, there are still millions of children in low and middle-income countries who are not covered by routine vaccines and remain at risk. The…

物理与社会 · 物理学 2021-04-30 Yuwen Yang , Hoda Bidkhori , Jayant Rajgopal

We formulate an optimal control problem to determine the lockdown policy to curb an epidemic where other control measures are not available yet. We present a unified framework to model the epidemic and economy that allows us to study the…

系统与控制 · 电气工程与系统科学 2022-01-20 Jagtap Kalyani Devendra , Kundan Kandhway
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