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Upcoming many core processors are expected to employ a distributed memory architecture similar to currently available supercomputers, but parallel pattern mining algorithms amenable to the architecture are not comprehensively studied. We…

分布式、并行与集群计算 · 计算机科学 2015-10-28 Kazuki Yoshizoe , Aika Terada , Koji Tsuda

Hyperdimensional computing (HDC) is an emerging computing paradigm that represents, manipulates, and communicates data using very long random vectors (aka hypervectors). Among different hardware platforms capable of executing HDC…

硬件体系结构 · 计算机科学 2022-05-24 Robert Guirado , Abbas Rahimi , Geethan Karunaratne , Eduard Alarcón , Abu Sebastian , Sergi Abadal

While high-dimensional search-by-similarity techniques reached their maturity and in overall provide good performance, most of them are unable to cope with very large multimedia collections. The 'big data' challenge however has to be…

信息检索 · 计算机科学 2015-02-02 Denis Shestakov , Diana Moise

In-memory database query processing frequently involves substantial data transfers between the CPU and memory, leading to inefficiencies due to Von Neumann bottleneck. Processing-in-Memory (PIM) architectures offer a viable solution to…

The ultimate target of proteomics identification is to identify and quantify the protein in the organism. Mass spectrometry (MS) based on label-free protein quantitation has mainly focused on analysis of peptide spectral counts and ion peak…

定量方法 · 定量生物学 2013-12-05 Biao He , Baochang Zhang , Yan Fu

Scientific applications produce vast amounts of data, posing grand challenges in the underlying data management and analytic tasks. Progressive compression is a promising way to address this problem, as it allows for on-demand data…

分布式、并行与集群计算 · 计算机科学 2025-05-02 Yanliang Li , Wenbo Li , Qian Gong , Qing Liu , Norbert Podhorszki , Scott Klasky , Xin Liang , Jieyang Chen

By coupling peptides with DNA tags (i.e., 'barcodes'), it is now possible to harness high-throughput sequencing (HTS) technologies to enable highly multiplexed peptide-based assays, which have a variety of potential applications including…

定量方法 · 定量生物学 2020-07-13 Zane W. Fink , Vidal Martinez , John Altin , Jason T. Ladner

Graph pattern matching, which aims to discover structural patterns in graphs, is considered one of the most fundamental graph mining problems in many real applications. Despite previous efforts, existing systems face two main challenges.…

分布式、并行与集群计算 · 计算机科学 2020-09-30 Tianhui Shi , Mingshu Zhai , Yi Xu , Jidong Zhai

The convergence of IoT, Edge, Cloud, and HPC technologies creates a compute continuum that merges cloud scalability and flexibility with HPC's computational power and specialized optimizations. However, integrating cloud and HPC resources…

分布式、并行与集群计算 · 计算机科学 2025-05-20 Aasish Kumar Sharma , Christian Boehme , Patrick Gelß , Ramin Yahyapour , Julian Kunkel

HEP-Frame is a new C++ package designed to efficiently perform analyses of data sets from a very large number of events, like those available at the Large Hadron Collider (LHC) at CERN, Geneva. It mainly targets high performance servers and…

高能物理 - 实验 · 物理学 2023-03-10 A. Pereira , A. Onofre , A. Proenca

Identification and alignment of three-dimensional folding of proteins may yield useful information about relationships too remote to be detected by conventional methods, such as sequence comparison, and may potentially lead to prediction of…

定量方法 · 定量生物学 2017-01-10 Barış Ekim

Most machine learning algorithms are configured by one or several hyperparameters that must be carefully chosen and often considerably impact performance. To avoid a time consuming and unreproducible manual trial-and-error process to find…

The current landscape of scientific research is widely based on modeling and simulation, typically with complexity in the simulation's flow of execution and parameterization properties. Execution flows are not necessarily straightforward…

分布式、并行与集群计算 · 计算机科学 2018-07-26 Eduardo Ponce , Brittany Stephenson , Suzanne Lenhart , Judy Day , Gregory D. Peterson

Recent neural architecture search (NAS) based approaches have made great progress in hyperspectral image (HSI) classification tasks. However, the architectures are usually optimized independently of the network weights, increasing searching…

计算机视觉与模式识别 · 计算机科学 2023-04-25 Di Wang , Bo Du , Liangpei Zhang , Dacheng Tao

Database Management Systems (DBMSs) are crucial for efficient data management and analytics, and are used in several different application domains. Due to the increasing volume of data a DBMS deals with, current processor-centric…

硬件体系结构 · 计算机科学 2025-04-03 Manos Frouzakis , Juan Gómez-Luna , Geraldo F. Oliveira , Mohammad Sadrosadati , Onur Mutlu

Identifying similar protein sequences is a core step in many computational biology pipelines such as detection of homologous protein sequences, generation of similarity protein graphs for downstream analysis, functional annotation and gene…

分布式、并行与集群计算 · 计算机科学 2020-10-01 Oguz Selvitopi , Saliya Ekanayake , Giulia Guidi , Georgios Pavlopoulos , Ariful Azad , Aydin Buluc

Hyperparameter optimization (HPO) is a critical component of machine learning pipelines, significantly affecting model robustness, stability, and generalization. However, HPO is often a time-consuming and computationally intensive task.…

机器学习 · 计算机科学 2025-03-10 Ruinan Wang , Ian Nabney , Mohammad Golbabaee

To achieve peak predictive performance, hyperparameter optimization (HPO) is a crucial component of machine learning and its applications. Over the last years, the number of efficient algorithms and tools for HPO grew substantially. At the…

When training deep learning models, the performance depends largely on the selected hyperparameters. However, hyperparameter optimization (HPO) is often one of the most expensive parts of model design. Classical HPO methods treat this as a…

Low-precision networks, with weights and activations quantized to low bit-width, are widely used to accelerate inference on edge devices. However, current solutions are uniform, using identical bit-width for all filters. This fails to…

机器学习 · 计算机科学 2020-04-14 Zhaowei Cai , Nuno Vasconcelos