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The evolution, regulation and sustenance of biological complexity is determined by protein-protein interaction network that is filled with dynamic events. Recent experimental evidences point out that clustering of proteins has a vital role…

组织与器官 · 定量生物学 2007-05-23 RV Krishnan

Photoactivatable ribonucleoside-enhanced cross-linking and immunoprecipitation (PAR-CLIP) is an experimental method based on next-generation sequencing for identifying the RNA interaction sites of a given protein. The method deliberately…

定量方法 · 定量生物学 2015-04-08 Monica Golumbeanu , Pejman Mohammadi , Niko Beerenwinkel

In this paper we study nonconvex and nonsmooth optimization problems with semi-algebraic data, where the variables vector is split into several blocks of variables. The problem consists of one smooth function of the entire variables vector…

最优化与控制 · 数学 2017-02-09 Thomas Pock , Shoham Sabach

This paper presents a novel calibration algorithm for Multi-Focus Plenoptic Cameras (MFPCs) using raw images only. The design of such cameras is usually complex and relies on precise placement of optic elements. Several calibration…

图像与视频处理 · 电气工程与系统科学 2021-11-10 Mathieu Labussière , Céline Teulière , Frédéric Bernardin , Omar Ait-Aider

Image processing and pattern recognition offer a useful and versatile method for optically characterizing drops of a colloidal solution during the drying process and in its final state. This paper exploits image processing techniques…

软凝聚态物质 · 物理学 2020-02-11 Anusuya Pal , Amalesh Gope , Germano S. Iannacchione

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

生物物理 · 物理学 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

Feature description is one of the most frequently studied areas in the expert systems and machine learning. Effective encoding of the images is an essential requirement for accurate matching. These encoding schemes play a significant role…

计算机视觉与模式识别 · 计算机科学 2022-01-04 Soumendu Chakraborty , Satish Kumar Singh , Pavan Chakraborty

In complex plasmas, the behavior of freely floating micrometer sized particles is studied. The particles can be directly visualized and recorded by digital video cameras. To analyze the dynamics of single particles, reliable algorithms are…

等离子体物理 · 物理学 2018-02-14 Daniel P. Mohr , Christina A. Knapek , Peter Huber , Erich Zaehringer

Semi-supervised clustering is the task of clustering data points into clusters where only a fraction of the points are labelled. The true number of clusters in the data is often unknown and most models require this parameter as an input.…

机器学习 · 计算机科学 2013-09-27 Amar Shah , Zoubin Ghahramani

Super-resolution imaging techniques have largely improved our capabilities to visualize nanometric structures in biological systems. Their application further enables one to potentially quantitate relevant parameters to determine the…

生物物理 · 物理学 2019-12-18 Tina Kosǔta , Marta Cullell-Dalmau , Francesca Cella Zanacchi , Carlo Manzo

The CALMA (Computer Assisted Library for MAmmography) project is a five years plan developed in a physics research frame in collaboration between INFN (Istituto Nazionale di Fisica Nucleare) and many Italian hospitals. At present a large…

医学物理 · 物理学 2009-11-10 A. Lauria , R. Palmiero , G. Forni , P. Cerello , B. Golosio , F. Fauci , R. Magro , G. Raso , S. Tangaro , P. L. Indovina

Microcalcifications are small deposits of calcium that appear in mammograms as bright white specks on the soft tissue background of the breast. Microcalcifications may be a unique indication for Ductal Carcinoma in Situ breast cancer, and…

计算机视觉与模式识别 · 计算机科学 2021-02-24 Roee Zamir , Shai Bagon , David Samocha , Yael Yagil , Ronen Basri , Miri Sklair-Levy Meirav Galun

Sparse Blind Source Separation (sparse BSS) is a key method to analyze multichannel data in fields ranging from medical imaging to astrophysics. However, since it relies on seeking the solution of a non-convex penalized matrix factorization…

机器学习 · 计算机科学 2018-12-18 Christophe Kervazo , Jerome Bobin , Cecile Chenot

Confocal laser-scanning microscopy (CLSM) is one of the most popular optical architectures for fluorescence imaging. In CLSM, a focused laser beam excites the fluorescence emission from a specific specimen position. Some actuators scan the…

图像与视频处理 · 电气工程与系统科学 2023-05-10 Alessandro Zunino , Marco Castello , Giuseppe Vicidomini

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

计算机视觉与模式识别 · 计算机科学 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

Accurate localization of proteins from fluorescence microscopy images is challenging due to the inter-class similarities and intra-class disparities introducing grave concerns in addressing multi-class classification problems. Conventional…

计算机视觉与模式识别 · 计算机科学 2021-10-11 Muhammad Tahir , Saeed Anwar , Ajmal Mian , Abdul Wahab Muzaffar

A crucial step in single particle analysis (SPA) of cryogenic electron microscopy (Cryo-EM), 2D classification and alignment takes a collection of noisy particle images to infer orientations and group similar images together. Averaging…

计算机视觉与模式识别 · 计算机科学 2022-06-28 Supawit Chockchowwat , Chandrajit L. Bajaj

Sparse Blind Source Separation (BSS) has become a well established tool for a wide range of applications - for instance, in astrophysics and remote sensing. Classical sparse BSS methods, such as the Proximal Alternating Linearized…

天体物理仪器与方法 · 物理学 2022-03-08 Mohammad Fahes , Christophe Kervazo , Jérôme Bobin , Florence Tupin

In this paper we address imbalanced binary classification (IBC) tasks. Applying resampling strategies to balance the class distribution of training instances is a common approach to tackle these problems. Many state-of-the-art methods find…

机器学习 · 计算机科学 2022-05-31 Vitor Cerqueira , Luis Torgo , Paula Branco , Colin Bellinger

Photonic integrated circuits offer a compact and stable platform for generating, manipulating, and detecting light. They are instrumental for classical and quantum applications. Imperfections stemming from fabrication constraints,…

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