相关论文: Private DNA Sequencing: Hiding Information in Disc…
Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…
DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…
DNA sequencing is becoming increasingly commonplace, both in medical and direct-to-consumer settings. To promote discovery, collected genomic data is often de-identified and shared, either in public repositories, such as OpenSNP, or with…
This is a paper about private data analysis, in which a trusted curator holding a confidential database responds to real vector-valued queries. A common approach to ensuring privacy for the database elements is to add appropriately…
Genomic data provides clinical researchers with vast opportunities to study various patient ailments. Yet the same data contains revealing information, some of which a patient might want to remain concealed. The question then arises: how…
Networked system often relies on distributed algorithms to achieve a global computation goal with iterative local information exchanges between neighbor nodes. To preserve data privacy, a node may add a random noise to its original data for…
DNA sequencing has faced a huge demand since it was first introduced as a service to the public. This service is often offloaded to the sequencing companies who will have access to full knowledge of individuals' sequences, a major violation…
Formal disclosure avoidance techniques are necessary to ensure that published data can not be used to identify information about individuals. The addition of statistical noise to unpublished data can be implemented to achieve differential…
In this paper, we study methods for improving the efficiency and privacy of compressed DNA sequence comparison computations, under various querying scenarios. For instance, one scenario involves a querier, Bob, who wants to test if his DNA…
Motivation: Researchers need a rich trove of genomic datasets that they can leverage to gain a better understanding of the genetic basis of the human genome and identify associations between phenotypes and specific parts of DNA. However,…
To protect user privacy in data analysis, a state-of-the-art strategy is differential privacy in which scientific noise is injected into the real analysis output. The noise masks individual's sensitive information contained in the dataset.…
In a world where artificial intelligence and data science become omnipresent, data sharing is increasingly locking horns with data-privacy concerns. Differential privacy has emerged as a rigorous framework for protecting individual privacy…
We develop statistically based methods to detect single nucleotide DNA mutations in next generation sequencing data. Sequencing generates counts of the number of times each base was observed at hundreds of thousands to billions of genome…
We consider the problem of storing and retrieving information from synthetic DNA media. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on their collection of substrings…
Differentially private noise mechanisms commonly use symmetric noise distributions. This is attractive both for achieving the differential privacy definition, and for unbiased expectations in the noised answers. However, there are contexts…
Data obfuscation deals with the problem of masking a data-set in such a way that the utility of the data is maximized while minimizing the risk of the disclosure of sensitive information. To protect data we address some ways that may as…
The problem of privately releasing data is to provide a version of a dataset without revealing sensitive information about the individuals who contribute to the data. The model of differential privacy allows such private release while…
Due to its longevity and enormous information density, DNA is an attractive medium for archival data storage. Thanks to rapid technological advances, DNA storage is becoming practically feasible, as demonstrated by a number of experimental…
We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…
The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…