相关论文: Incorporating Expert Guidance in Epidemic Forecast…

A crucial aspect of managing a public health crisis is to effectively balance prevention and mitigation strategies, while taking their socio-economic impact into account. In particular, determining the influence of different…

The authors propose a robust semi-parametric empirical likelihood method to integrate all available information from multiple samples with a common center of measurements. Two different sets of estimating equations are used to improve the…

Estimating the true prevalence of an epidemic outbreak is a key public health problem. This is challenging because surveillance is usually resource intensive and biased. In the network setting, prior work on cost sensitive disease…

This paper proposes a novel approach to predict epidemiological parameters by integrating new real-time signals from various sources of information, such as novel social media-based population density maps and Air Quality data. We implement…

This study applied Bayesian optimization likelihood-free inference(BOLFI) to virus dynamics experimental data and efficiently inferred the model parameters with uncertainty measure. The computational benefit is remarkable compared to…

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Accurate and reliable forecasting of epidemic incidences is critical for public health preparedness, yet it remains a challenging task due to complex nonlinear temporal dependencies and heterogeneous spatial interactions. Often, point…

Many epidemic models are naturally defined as individual-based models: where we track the state of each individual within a susceptible population. Inference for individual-based models is challenging due to the high-dimensional state-space…

We introduce a fast simulation technique for modeling epidemics on adaptive networks. Our rejection-based algorithm efficiently simulates the co-evolution of the network structure and the epidemic dynamics. We extend the classical SIS model…

The influenza virus hemagglutinin is an important part of the virus attachment to the host cells. The hemagglutinin proteins are one of the genetic regions of the virus with a high potential for mutations. Due to the importance of…

Deep neural networks are increasingly employed in high-stakes medical applications, despite their tendency for shortcut learning in the presence of spurious correlations, which can have potentially fatal consequences in practice. Whereas a…

Machine learning for early prediction in medicine has recently shown breakthrough performance, however, the focus on improving prediction accuracy has led to a neglect of faithful explanations that are required to gain the trust of medical…

Forecasting infectious disease incidence can provide important information to guide public health planning, yet is difficult because epidemic dynamics are complex. Current mechanistic and statistical approaches often struggle to capture…

We propose a novel adaptive Mixture-of-Experts (MoE) framework for time series forecasting that enhances expert specialization by incorporating expert-specific loss information directly into the training process. Notably, the overall…

Ensemble forecasts have become a cornerstone of large-scale disease response, underpinning decision making at agencies such as the US Centers for Disease Control and Prevention (CDC). Their growing use reflects the goal of combining…

For epidemics control and prevention, timely insights of potential hot spots are invaluable. Alternative to traditional epidemic surveillance, which often lags behind real time by weeks, big data from the Internet provide important…

Motivated by the ongoing pandemic COVID-19, we propose a closed-loop framework that combines inference from testing data, learning the parameters of the dynamics and optimal resource allocation for controlling the spread of the…

The evolution of the COVID-19 epidemic has been accompanied by accumulating evidence on the underlying epidemiological parameters. Hence there is potential for models providing mid-term forecasts of the epidemic trajectory using such…

Epidemiological models increasingly rely on self-reported behavioral data such as vaccination status, mask usage, and social distancing adherence to forecast disease transmission and assess the impact of non-pharmaceutical interventions…

Health data are often not symmetric to be adequately modeled through the usual normal distributions; most of them exhibit skewed patterns. They can indeed be modeled better through the larger family of skew-normal distributions covering…