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A prompt public health response to a new epidemic relies on the ability to monitor and predict its evolution in real time as data accumulate. The 2009 A/H1N1 outbreak in the UK revealed pandemic data as noisy, contaminated, potentially…

Infectious disease forecasts can reduce mortality and morbidity by supporting evidence-based public health decision making. Most epidemic models train on surveillance and structured data (e.g. weather, mobility, media), missing contextual…

The estimation from available data of parameters governing epidemics is a major challenge. In addition to usual issues (data often incomplete and noisy), epidemics of the same nature may be observed in several places or over different…

统计方法学 · 统计学 2021-09-20 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Infectious diseases are one of the leading causes of morbidity and mortality around the world; thus, forecasting their impact is crucial for planning an effective response strategy. According to the Centers for Disease Control and…

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

社会与信息网络 · 计算机科学 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

Influenza remains a significant burden on health systems. Effective responses rely on the timely understanding of the magnitude and the evolution of an outbreak. For monitoring purposes, data on severe cases of influenza in England are…

Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

应用统计 · 统计学 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

Despite the recent development of methods dealing with partially observed epidemic dynamics (unobserved model coordinates, discrete and noisy outbreak data), limitations remain in practice, mainly related to the quantity of augmented data…

应用统计 · 统计学 2021-07-26 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

AI Epidemiology is a framework for governing and explaining advanced AI systems by applying population-level surveillance methods to AI outputs. The approach mirrors the way in which epidemiologists enable public health interventions…

人工智能 · 计算机科学 2026-02-23 Kit Tempest-Walters

Forecasting influenza in a timely manner aids health organizations and policymakers in adequate preparation and decision making. However, effective influenza forecasting still remains a challenge despite increasing research interest. It is…

Estimates from infectious disease models have constituted a significant part of the scientific evidence used to inform the response to the COVID-19 pandemic in the UK. These estimates can vary strikingly in their bias and variability.…

应用统计 · 统计学 2022-10-12 R. E. Moore , C. Rosato , S. Maskell

The accurate forecasting of infectious epidemic diseases such as influenza is a crucial task undertaken by medical institutions. Although numerous flu forecasting methods and models based mainly on historical flu activity data and online…

机器学习 · 计算机科学 2021-07-08 Taichi Murayama , Shoko Wakamiya , Eiji Aramaki

Traditional epidemic detection algorithms make decisions using only local information. We propose a novel approach that explicitly models spatial information fusion from several metapopulations. Our method also takes into account…

统计计算 · 统计学 2015-09-15 Michael Ludkovski , Katherine Shatskikh

Recent pandemics have highlighted the critical role of infectious disease models in guiding public health decision-making, driving demand for realistic models that can provide timely answers under uncertainty. Compartmental models are…

统计方法学 · 统计学 2026-03-18 Xiahui Li , Fergus J. Chadwick , Ben Swallow

A central challenge in every field of biology is to use existing measurements to predict the outcomes of future experiments. In this work, we consider the wealth of antibody inhibition data against variants of the influenza virus. Due to…

定量方法 · 定量生物学 2023-07-27 Tal Einav , Rong Ma

Epidemics of infectious diseases are an important threat to public health and global economies. Yet, the development of prevention strategies remains a challenging process, as epidemics are non-linear and complex processes. For this reason,…

Advanced epidemic forecasting is critical for enabling precision containment strategies, highlighting its strategic importance for public health security. While recent advances in Large Language Models (LLMs) have demonstrated effectiveness…

机器学习 · 计算机科学 2025-05-20 Chenghua Gong , Rui Sun , Yuhao Zheng , Juyuan Zhang , Tianjun Gu , Liming Pan , Linyuan Lv

This paper presents a state estimation-based robust optimal control strategy for influenza epidemics in an interactive human society in the presence of modeling uncertainties. Interactive society is influenced by the random entrance of…

系统与控制 · 电气工程与系统科学 2020-11-12 Vahid Azimi , Mojtaba Sharifi , Seyed Fakoorian , Thang Tien Nguyen , Van Van Huynh

Accurate epidemic forecasting is critical for effective public health interventions. This study compares Bayesian and Frequentist estimation frameworks within deterministic compartmental epidemic models, focusing on nonlinear least squares…

定量方法 · 定量生物学 2025-09-09 Hamed Karami , Ruiyan Luo , Pejman Sanaei , Gerardo Chowell

The seasonality of respiratory diseases (common cold, influenza, etc.) is a well-known phenomenon studied from ancient times. The development of predictive models is still not only an actual unsolved problem of mathematical epidemiology but…

种群与进化 · 定量生物学 2014-04-28 Eugene B. Postnikov , Dmitry V. Tatarenkov