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The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Electronic health records (EHR) are characterized as non-stationary, heterogeneous, noisy, and sparse data; therefore, it is challenging to learn the regularities or patterns inherent within them. In particular, sparseness caused mostly by…

机器学习 · 计算机科学 2020-03-03 Eunji Jun , Ahmad Wisnu Mulyadi , Jaehun Choi , Heung-Il Suk

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

机器学习 · 计算机科学 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

机器学习 · 计算机科学 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to…

机器学习 · 计算机科学 2026-03-16 Dingyi Nie , Yixing Wu , C. -C. Jay Kuo

Electronic health records (EHR) are rich heterogeneous collection of patient health information, whose broad adoption provides great opportunities for systematic health data mining. However, heterogeneous EHR data types and biased…

机器学习 · 计算机科学 2018-11-02 Yue Li , Manolis Kellis

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

定量方法 · 定量生物学 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Irregular time series, where data points are recorded at uneven intervals, are prevalent in healthcare settings, such as emergency wards where vital signs and laboratory results are captured at varying times. This variability, which…

机器学习 · 计算机科学 2024-10-16 Hrishikesh Patel , Ruihong Qiu , Adam Irwin , Shazia Sadiq , Sen Wang

Clinical time series derived from electronic health records (EHRs) are inherently irregular, with asynchronous sampling, missing values, and heterogeneous feature dynamics. While numerical laboratory measurements are highly informative,…

人工智能 · 计算机科学 2025-11-13 Yi-Hsien Hsieh , Ta-Jung Chien , Chun-Kai Huang , Shao-Hua Sun , Che Lin

Longitudinal electronic health record (EHR) data offer opportunities to study biomarker trajectories; however, association estimates-the primary inferential target-from standard models designed for regular observation times may be biased by…

统计方法学 · 统计学 2026-02-18 Cheng-Han Yang , Xu Shi , Bhramar Mukherjee

Electronic health record (EHR) data are becoming an increasingly common data source for understanding clinical risk of acute events. While their longitudinal nature presents opportunities to observe changing risk over time, these analyses…

Doctors often make diagonostic decisions based on patient's image scans, such as magnetic resonance imaging (MRI), and patient's electronic health records (EHR) such as age, gender, blood pressure and so on. Despite a lot of automatic…

计算机视觉与模式识别 · 计算机科学 2021-12-23 Cheng Jiang , Yihao Chen , Jianbo Chang , Ming Feng , Renzhi Wang , Jianhua Yao

The inherent multimodality and heterogeneous temporal structures of medical data pose significant challenges for modeling. We propose MedM2T, a time-aware multimodal framework designed to address these complexities. MedM2T integrates: (i)…

机器学习 · 计算机科学 2026-03-26 Yu-Chen Kuo , Yi-Ju Tseng

Electronic Health Records (EHRs) contain rich, longitudinal patient information across structured (e.g., labs, vitals, and imaging) and unstructured (e.g., clinical notes) modalities. While deep learning models such as RNNs and Transformers…

机器学习 · 计算机科学 2026-02-18 Mohammad Al Olaimat , Shaika Chowdhury , Serdar Bozdag

Learning from longitudinal electronic health records is limited if it does not capture the temporal trajectories of the patient's state in a clinical setting. Graph models allow us to capture the hidden dependencies of the multivariate…

机器学习 · 计算机科学 2025-03-31 Munib Mesinovic , Soheila Molaei , Peter Watkinson , Tingting Zhu

Multimodal clinical records contain structured measurements and clinical notes recorded over time, offering rich temporal information about the evolution of patient health. Yet these observations are sparse, and whether they are recorded…

机器学习 · 计算机科学 2026-04-24 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Analysis of multivariate healthcare time series data is inherently challenging: irregular sampling, noisy and missing values, and heterogeneous patient groups with different dynamics violating exchangeability. In addition, interpretability…

机器学习 · 计算机科学 2023-11-15 Onur Poyraz , Pekka Marttinen

Predicting the patient's clinical outcome from the historical electronic medical records (EMR) is a fundamental research problem in medical informatics. Most deep learning-based solutions for EMR analysis concentrate on learning the…

机器学习 · 计算机科学 2019-11-28 Liantao Ma , Chaohe Zhang , Yasha Wang , Wenjie Ruan , Jiantao Wang , Wen Tang , Xinyu Ma , Xin Gao , Junyi Gao

Time series data in real-world applications such as healthcare, climate modeling, and finance are often irregular, multimodal, and messy, with varying sampling rates, asynchronous modalities, and pervasive missingness. However, existing…

机器学习 · 计算机科学 2025-10-16 Ching Chang , Jeehyun Hwang , Yidan Shi , Haixin Wang , Wen-Chih Peng , Tien-Fu Chen , Wei Wang

Feature engineering for Electronic Health Records (EHR) is complicated by irregular observation intervals, variable measurement frequencies, and structural sparsity inherent to clinical time series. Existing automated methods either lack…

机器学习 · 计算机科学 2026-04-27 Hojjat Karami , David Atienza , Jean-Philippe Thiran , Anisoara Ionescu