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Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Pretraining multimodal models on Electronic Health Records (EHRs) provides a means of learning representations that can transfer to downstream tasks with minimal supervision. Recent multimodal models induce soft local alignments between…

机器学习 · 计算机科学 2023-02-27 Denis Jered McInerney , Geoffrey Young , Jan-Willem van de Meent , Byron C. Wallace

Biobanks with genetics-linked electronic health records (EHR) have opened up opportunities to study associations between genetic, social, or environmental factors and longitudinal lab biomarkers. However, in EHRs, the timing of patient…

统计方法学 · 统计学 2025-05-23 Jiacong Du , Xu Shi , Bhramar Mukherjee

Modeling continuous-time physiological processes that manifest a patient's evolving clinical states is a key step in approaching many problems in healthcare. In this paper, we develop the Hidden Absorbing Semi-Markov Model (HASMM): a…

人工智能 · 计算机科学 2016-12-28 Ahmed M. Alaa , Mihaela van der Schaar

Time series data are prevalent in electronic health records, mostly in the form of physiological parameters such as vital signs and lab tests. The patterns of these values may be significant indicators of patients' clinical states and there…

机器学习 · 计算机科学 2019-11-18 Kun Zhang , Yuan Xue , Gerardo Flores , Alvin Rajkomar , Claire Cui , Andrew M. Dai

Many real-world Electronic Health Record (EHR) data contains a large proportion of missing values. Leaving substantial portion of missing information unaddressed usually causes significant bias, which leads to invalid conclusion to be…

机器学习 · 计算机科学 2020-11-04 Lucas J. Liu , Hongwei Zhang , Jianzhong Di , Jin Chen

With the recent availability of Electronic Health Records (EHR) and great opportunities they offer for advancing medical informatics, there has been growing interest in mining EHR for improving quality of care. Disease diagnosis due to its…

人工智能 · 计算机科学 2018-04-24 Anahita Hosseini , Ting Chen , Wenjun Wu , Yizhou Sun , Majid Sarrafzadeh

Clinical notes in Electronic Health Records (EHR) present rich documented information of patients to inference phenotype for disease diagnosis and study patient characteristics for cohort selection. Unsupervised user embedding aims to…

计算与语言 · 计算机科学 2022-03-30 Xiaolei Huang , Franck Dernoncourt , Mark Dredze

Time series data with missing values is common across many domains. Healthcare presents special challenges due to prolonged periods of sensor disconnection. In such cases, having a confidence measure for imputed values is critical. Most…

机器学习 · 计算机科学 2025-07-15 Addison Weatherhead , Anna Goldenberg

Mobile health has emerged as a major success for tracking individual health status, due to the popularity and power of smartphones and wearable devices. This has also brought great challenges in handling heterogeneous, multi-resolution data…

统计方法学 · 统计学 2024-05-31 Jiuchen Zhang , Fei Xue , Qi Xu , Jung-Ah Lee , Annie Qu

In longitudinal studies using routinely collected data, such as electronic health records (EHRs), patients tend to have more measurements when they are unwell; this informative observation pattern may lead to bias. While semi-parametric…

统计方法学 · 统计学 2024-10-02 Rose Garrett , Brian Feldman , Eleanor Pullenayegum

Monitoring complex systems results in massive multivariate time series data, and anomaly detection of these data is very important to maintain the normal operation of the systems. Despite the recent emergence of a large number of anomaly…

机器学习 · 计算机科学 2021-06-14 Liwei Deng , Xuanhao Chen , Yan Zhao , Kai Zheng

Modern electronic health records (EHRs) hold immense promise in tracking personalized patient health trajectories through sequential deep learning, owing to their extensive breadth, scale, and temporal granularity. Nonetheless, how to…

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

人工智能 · 计算机科学 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

机器学习 · 计算机科学 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Deep learning-based modeling of multimodal Electronic Health Records (EHRs) has become an important approach for clinical diagnosis and risk prediction. However, due to diverse clinical workflows and privacy constraints, raw EHRs are…

机器学习 · 计算机科学 2026-04-09 Bohao Li , Tao Zou , Junchen Ye , Yan Gong , Bowen Du

Missing values in electronic health record (EHR) data pose a significant challenge for epidemiologic research. Traditional methods for handling missing data, like mean imputation, may introduce bias. Multiple imputation (MI) offers a…

Electronic health record (EHR) is more and more popular, and it comes with applying machine learning solutions to resolve various problems in the domain. This growing research area also raises the need for EHRs accessibility. Medical…

机器学习 · 计算机科学 2024-01-30 Hung Bui , Harikrishna Warrier , Yogesh Gupta

Multimodal electronic health record (EHR) data are widely used in clinical applications. Conventional methods usually assume that each sample (patient) is associated with the unified observed modalities, and all modalities are available for…

机器学习 · 计算机科学 2022-11-01 Chaohe Zhang , Xu Chu , Liantao Ma , Yinghao Zhu , Yasha Wang , Jiangtao Wang , Junfeng Zhao

Predicting multivariate time series is crucial, demanding precise modeling of intricate patterns, including inter-series dependencies and intra-series variations. Distinctive trend characteristics in each time series pose challenges, and…

机器学习 · 计算机科学 2024-07-08 Guoqi Yu , Jing Zou , Xiaowei Hu , Angelica I. Aviles-Rivero , Jing Qin , Shujun Wang