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Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

Whole slide images~(WSIs) are digitized images of tissues placed in glass slides using advanced scanners. The digital processing of WSIs is challenging as they are gigapixel images and stored in multi-resolution format. A common challenge…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

计算机视觉与模式识别 · 计算机科学 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

Digital pathology provides an excellent opportunity for applying fully convolutional networks (FCNs) to tasks, such as semantic segmentation of whole slide images (WSIs). However, standard FCNs face challenges with respect to…

计算机视觉与模式识别 · 计算机科学 2018-07-26 Feng Gu , Nikolay Burlutskiy , Mats Andersson , Lena Kajland Wilen

In this paper, we propose a novel method for highly efficient follicular segmentation of thyroid cytopathological WSIs. Firstly, we propose a hybrid segmentation architecture, which integrates a classifier into Deeplab V3 by adding a…

计算机视觉与模式识别 · 计算机科学 2019-02-15 Siyan Tao , Yao Guo , Chuang Zhu , Huang Chen , Yue Zhang , Jie Yang , Jun Liu

Regions of Interest (ROI) contain morphological features in pathology whole slide images (WSI) are delimited with polygons[1]. These polygons are often represented in either a textual notation (with the array of edges) or in a binary mask…

图形学 · 计算机科学 2020-05-15 Erich Bremer , Jonas Almeida , Joel Saltz

In recent years, the use of deep learning (DL) methods, including convolutional neural networks (CNNs) and vision transformers (ViTs), has significantly advanced computational pathology, enhancing both diagnostic accuracy and efficiency.…

Recent advancements in whole slide imaging (WSI) have moved pathology closer to digital practice. Existing systems require precise mechanical control and the cost is prohibitive for most individual pathologists. Here we report a low-cost…

图像与视频处理 · 电气工程与系统科学 2019-12-30 Chengfei Guo , Zichao Bian , Shaowei Jiang , Michael Murphy , Jiakai Zhu , Ruihai Wang , Pengming Song , Xiaopeng Shao , Yongbing Zhang , Guoan Zheng

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

图像与视频处理 · 电气工程与系统科学 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

Digital pathology and the integration of artificial intelligence (AI) models have revolutionized histopathology, opening new opportunities. With the increasing availability of Whole Slide Images (WSIs), there's a growing demand for…

图像与视频处理 · 电气工程与系统科学 2024-04-30 Areej Alsaafin , Peyman Nejat , Abubakr Shafique , Jibran Khan , Saghir Alfasly , Ghazal Alabtah , H. R. Tizhoosh

The advancement of digital pathology, particularly through computational analysis of whole slide images (WSI), is poised to significantly enhance diagnostic precision and efficiency. However, the large size and complexity of WSIs make it…

计算机视觉与模式识别 · 计算机科学 2024-11-14 Ravi Kant Gupta , Dadi Dharani , Shambhavi Shanker , Amit Sethi

Mycosis fungoides (MF) is a rare, potentially life threatening skin disease, which in early stages clinically and histologically strongly resembles Eczema, a very common and benign skin condition. In order to increase the survival rate, one…

图像与视频处理 · 电气工程与系统科学 2020-09-14 Jérémy Scheurer , Claudio Ferrari , Luis Berenguer Todo Bom , Michaela Beer , Werner Kempf , Luis Haug

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

计算机视觉与模式识别 · 计算机科学 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

In histopathology, tissue samples are often larger than a standard microscope slide, making stitching of multiple fragments necessary to process entire structures such as tumors. Automated stitching is a prerequisite for scaling analysis,…

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…

计算机视觉与模式识别 · 计算机科学 2025-10-30 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Khang Nguyen , Yasuhiko Nakashima

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

图像与视频处理 · 电气工程与系统科学 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

The domain shift in pathological segmentation is an important problem, where a network trained by a source domain (collected at a specific hospital) does not work well in the target domain (from different hospitals) due to the different…

计算机视觉与模式识别 · 计算机科学 2023-04-27 Xiaoqing Liu , Kengo Araki , Shota Harada , Akihiko Yoshizawa , Kazuhiro Terada , Mariyo Kurata , Naoki Nakajima , Hiroyuki Abe , Tetsuo Ushiku , Ryoma Bise

Whole slide imaging (WSI) has become the primary modality for digital pathology data. However, due to the size and high-resolution nature of these images, they are generally only accessed in smaller sections or tiles via specialized…

Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…

图像与视频处理 · 电气工程与系统科学 2021-06-15 Shivam Kalra , Mohammed Adnan , Sobhan Hemati , Taher Dehkharghanian , Shahryar Rahnamayan , Hamid Tizhoosh