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Background: Many studies have been conducted on the genetic and epigenetic etiology of gestational diabetes mellitus (GDM) in the last two decades because of the diseases increasing prevalence and role in the global diabetes mellitus (DM)…

基因组学 · 定量生物学 2021-01-20 Tajudeen Yahaya , Titilola Salisu , Yusuf Abdulrahman , Abdulrazak Umar

Single gene mutations have been implicated in the pathogenesis of a form of diabetes mellitus (DM) known as the maturity-onset diabetes of the young (MODY). However, there are diverse opinions on the suspect genes and pathophysiology,…

基因组学 · 定量生物学 2021-01-19 Tajudeen O. Yahaya , Shemishere B. Ufuoma

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to impaired insulin production or function. Two main forms are recognized: type 1 diabetes (T1D), which involves autoimmune destruction of…

基因组学 · 定量生物学 2026-02-11 Maria De La Luz Lomboy Toledo , Daniel Onah

Type 1 Diabetes is a chronic autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in little to no insulin production. Insulin helps glucose in your blood enter your…

定量方法 · 定量生物学 2025-02-04 Soon Jynn Chu , Nalaka Amarasiri , Sandesh Giri , Priyata Kafle

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

机器学习 · 计算机科学 2026-04-27 Beyza Cinar , Maria Maleshkova

Diabetes mellitus is a common disease of human body caused by a group of metabolic disorders where the sugar levels over a prolonged period is very high. It affects different organs of the human body which thus harm a large number of the…

机器学习 · 计算机科学 2019-02-27 Md. Faisal Faruque , Asaduzzaman , Iqbal H. Sarker

The rising prevalence of type 2 diabetes mellitus (T2DM) necessitates the development of predictive models for T2DM risk assessment. Artificial intelligence (AI) models are being extensively used for this purpose, but a comprehensive review…

机器学习 · 计算机科学 2023-05-29 Farida Mohsen , Hamada R. H. Al-Absi , Noha A. Yousri , Nady El Hajj , Zubair Shah

Disease progression varies with age and is influenced by underlying genetic, biochemical, and hormonal etiologies, suggesting the need for tailored monitoring, care, and medication beyond standard clinical guidelines. Specifically, in…

机器学习 · 计算机科学 2026-04-28 Beyza Cinar , Maria Maleshkova

The global prevalence of diabetes, particularly type 2 diabetes mellitus (T2DM), is rapidly increasing, posing significant health and economic challenges. T2DM not only disrupts blood glucose regulation but also damages vital organs such as…

机器学习 · 计算机科学 2025-06-09 Praveen Kumar , Vincent T. Metzger , Scott A. Malec

Effective patient education is critical for managing Type 2 Diabetes Mellitus (T2DM), one of the most common chronic diseases in the United States. While some studies focus on the information-seeking behavior of T2DM patients, other…

人机交互 · 计算机科学 2019-10-29 Sarah Masud Preum , Kate Clark , Ashley Davis , Konstantine Khutsishvilli , Rupa S Valdez

Understanding the complex relationships of biomarkers in diabetes is pivotal for advancing treatment strategies, a pressing need in diabetes research. This study applies Bayesian network structure learning to analyze the Shanghai Type 1 and…

定量方法 · 定量生物学 2024-06-26 Yuyang Sun , Jingyu Lei , Panagiotis Kosmas

Diabetes has emerged as a significant global health issue, especially with the increasing number of cases in many countries. This trend Underlines the need for a greater emphasis on early detection and proactive management to avert or…

机器学习 · 计算机科学 2025-06-16 Mowafaq Salem Alzboon , Muhyeeddin Alqaraleh , Mohammad Subhi Al-Batah

Prediction of diabetes and its various complications has been studied in a number of settings, but a comprehensive overview of problem setting for diabetes prediction and care management has not been addressed in the literature. In this…

Diabetes mellitus is a global health crisis characterized by poor blood sugar regulation, impacting millions of people worldwide and leading to severe complications and mortality. Although Type 1 Diabetes Mellitus (T1DM) has a lower number…

其他定量生物学 · 定量生物学 2025-04-14 Rinrada Jadsadaphongphaibool , Dadi Bi , Christian D. Lorenz , Yansha Deng , Robert Schober

Diabetes mellitus is a disease that affects to hundreds of millions of people worldwide. Maintaining a good control of the disease is critical to avoid severe long-term complications. In recent years, several artificial pancreas systems…

This work concerns the identification of the allelic sequences of the DQB1 gene of the human leukocyte antigen system conferring susceptibility to the development of insulin-dependent diabetes mellitus (IDDM) in DNA samples with no need of…

基因组学 · 定量生物学 2011-12-13 Luca Nardo , Giovanna Tosi , Maria Bondani , Roberto S. Accolla , Alessandra Andreoni

Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

机器学习 · 计算机科学 2026-01-22 Giorgia Rigamonti , Mirko Paolo Barbato , Davide Marelli , Paolo Napoletano

In this study, we delve into the intricate relationships between diabetes and a range of health indicators, with a particular focus on the newly added variable of income. Utilizing data from the 2015 Behavioral Risk Factor Surveillance…

机器学习 · 计算机科学 2024-04-23 Fariba Jafari Horestani , M. Mehdi Owrang O

Type 1 Diabetes (T1D) is an autoimmune disease leading to insulin insufficiency. Thus, patients require lifelong insulin therapy, which has a side effect of hypoglycemia. Hypoglycemia is a critical state of decreased blood glucose levels…

机器学习 · 计算机科学 2026-01-21 Beyza Cinar , Louisa van den Boom , Maria Maleshkova

Background: Advanced biological techniques have helped produce more insightful findings on the genetic etiology of infertility that may lead to better management of the condition. This review provides an update on genes predisposing to…

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