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相关论文: Large-Scale Extended Granger Causality for Classif…

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A novel approach is developed for discovering directed connectivity between specified pairs of nodes in a high-dimensional network (HDN) of brain signals. To accurately identify causal connectivity for such specified objectives, it is…

应用统计 · 统计学 2025-05-06 Sipan Aslan , Hernando Ombao

The causal relationships between biomarkers are essential for disease diagnosis and medical treatment planning. One notable application is Alzheimer's disease (AD) diagnosis, where certain biomarkers may influence the presence of others,…

信息检索 · 计算机科学 2025-06-13 Xiaofan Zhou , Liangjie Huang , Pinyang Cheng , Wenpen Yin , Rui Zhang , Wenrui Hao , Lu Cheng

Granger causality has been employed to investigate causality relations between components of stationary multiple time series. We generalize this concept by developing statistical inference for local Granger causality for multivariate…

统计方法学 · 统计学 2025-08-12 Yan Liu , Masanobu Taniguchi , Hernando Ombao

Granger causality has been used for the investigation of the inter-dependence structure of the underlying systems of multi-variate time series. In particular, the direct causal effects are commonly estimated by the conditional Granger…

统计方法学 · 统计学 2016-04-20 Elsa Siggiridou , Dimitris Kugiumtzis

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

神经元与认知 · 定量生物学 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

There is increasing interest in identifying changes in the underlying states of brain networks. The availability of large scale neuroimaging data creates a strong need to develop fast, scalable methods for detecting and localizing in time…

统计方法学 · 统计学 2022-01-11 Peiliang Bai , Abolfazl Safikhani , George Michailidis

Functional alterations in the relevant neural circuits occur from drug addiction over a certain period. And these significant alterations are also revealed by analyzing fMRI. However, because of fMRI's high dimensionality and poor…

图像与视频处理 · 电气工程与系统科学 2022-07-12 Changwei Gong , Changhong Jing , Junren Pan , Shuqiang Wang

This paper considers joint learning of multiple sparse Granger graphical models to discover underlying common and differential Granger causality (GC) structures across multiple time series. This can be applied to drawing group-level brain…

机器学习 · 计算机科学 2021-05-25 Parinthorn Manomaisaowapak , Jitkomut Songsiri

Granger causality is widely used for causal structure discovery in complex systems from multivariate time series data. Traditional Granger causality tests based on linear models often fail to detect even mild non-linear causal…

机器学习 · 计算机科学 2025-10-23 Ziyi Zhang , Shaogang Ren , Xiaoning Qian , Nick Duffield

We propose a matrix factorization technique that decomposes the resting state fMRI (rs-fMRI) correlation matrices for a patient population into a sparse set of representative subnetworks, as modeled by rank one outer products. The…

信号处理 · 电气工程与系统科学 2018-07-26 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

Alzheimer's Disease (AD) is the world leading cause of dementia, a progressively impairing condition leading to high hospitalization rates and mortality. To optimize the diagnostic process, numerous efforts have been directed towards the…

图像与视频处理 · 电气工程与系统科学 2025-01-20 Davide Coluzzi , Valentina Bordin , Massimo Walter Rivolta , Igor Fortel , Liang Zhang , Alex Leow , Giuseppe Baselli

We consider the estimation of large covariance and precision matrices from high-dimensional sub-Gaussian or heavier-tailed observations with slowly decaying temporal dependence. The temporal dependence is allowed to be long-range so with…

统计理论 · 数学 2019-12-23 Hai Shu , Bin Nan

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

组织与器官 · 定量生物学 2026-04-17 Qianyu Chen , Shujian Yu

Granger causality, commonly used for inferring causal structures from time series data, has been adopted in widespread applications across various fields due to its intuitive explainability and high compatibility with emerging deep neural…

机器学习 · 计算机科学 2024-06-18 Ziyi Zhang , Shaogang Ren , Xiaoning Qian , Nick Duffield

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

统计方法学 · 统计学 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of…

Parkinsons disease (PD) is a movement disorder and the second most common neurodengerative disease but despite its relative abundance, there are no clinically accepted neuroimaging biomarkers to make prognostic predictions or differentiate…

神经元与认知 · 定量生物学 2022-06-23 Cooper J. Mellema , Kevin P. Nguyen , Alex Treacher , Aixa Andrade Hernandez , Albert A. Montillo

With the advancement of deep learning technologies, various neural network-based Granger causality models have been proposed. Although these models have demonstrated notable improvements, several limitations remain. Most existing approaches…

机器学习 · 计算机科学 2025-10-28 Meiliang Liu , Huiwen Dong , Xiaoxiao Yang , Yunfang Xu , Zijin Li , Zhengye Si , Xinyue Yang , Zhiwen Zhao

Effective connectivity can describe the causal patterns among brain regions. These patterns have the potential to reveal the pathological mechanism and promote early diagnosis and effective drug development for cognitive disease. However,…

计算机视觉与模式识别 · 计算机科学 2024-06-04 Qiankun Zuo , Hao Tian , Chi-Man Pun , Hongfei Wang , Yudong Zhang , Jin Hong

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

机器学习 · 统计学 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara