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Anatomical connectivity between different regions in the brain can be mapped to a network representation, the connectome, where the intensities of the links, the weights, influence its structural resilience and the functional processes it…

神经元与认知 · 定量生物学 2025-04-09 Laia Barjuan , Muhua Zheng , M. Ángeles Serrano

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

神经与进化计算 · 计算机科学 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

The human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. This result, however, may be limited methodologically. Past…

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

The architecture of the human connectome supports efficient communication protocols relying either on distances between brain regions or on the intensities of connections. However, none of these protocols combines information about the two…

神经元与认知 · 定量生物学 2024-10-07 Laia Barjuan , Jordi Soriano , M. Ángeles Serrano

The human connectome represents a network map of the brain's wiring diagram and the pattern into which its connections are organized is thought to play an important role in cognitive function. The generative rules that shape the topology of…

In mapping the human structural connectome, we are in a very fortunate situation: one can compute and compare graphs, describing the cerebral connections between the very same, anatomically identified small regions of the gray matter among…

神经元与认知 · 定量生物学 2017-12-01 Mate Fellner , Balint Varga , Vince Grolmusz

Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the…

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

神经元与认知 · 定量生物学 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

应用统计 · 统计学 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

The structural human connectome (i.e.\ the network of fiber connections in the brain) can be analyzed at ever finer spatial resolution thanks to advances in neuroimaging. Here we analyze several large data sets for the human brain network…

神经元与认知 · 定量生物学 2016-06-08 Michael T. Gastner , Géza Ódor

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

The human connectome at the level of fiber tracts between brain regions has been shown to differ in patients with brain disorders compared to healthy control groups. Nonetheless, there is a potentially large number of different network…

神经元与认知 · 定量生物学 2013-10-16 Marcus Kaiser

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

神经元与认知 · 定量生物学 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Finding the common structural brain connectivity network for a given population is an open problem, crucial for current neuro-science. Recent evidence suggests there's a tightly connected network shared between humans. Obtaining this…

神经元与认知 · 定量生物学 2017-01-10 Nahuel Lascano , Guillermo Gallardo , Rachid Deriche , Dorian Mazauric , Demian Wassermann

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

神经元与认知 · 定量生物学 2011-12-23 Marcus Kaiser

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

统计方法学 · 统计学 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with…

机器学习 · 统计学 2021-09-14 Meimei Liu , Zhengwu Zhang , David B. Dunson

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

神经元与认知 · 定量生物学 2024-09-13 Yizi Zhang , Meimei Liu , Zhengwu Zhang , David Dunson
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