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We optimized designs of permanent magnet systems to study the effect of magnetic nanoparticles on cell cultures in microslide channels. This produced two designs, one of which is based on a large cylindrical magnet that applies a uniform…

生物物理 · 物理学 2024-01-04 Leon Abelmann , Eunheui Gwag , Baeckkyoung Sung

Untethered magnetic manipulation of biomedical millirobots has a high potential for minimally invasive surgical applications. However, it is still challenging to exert high actuation forces on the small robots over a large distance.…

机器人学 · 计算机科学 2025-11-25 Ann-Sophia Müller , Moonkwang Jeong , Jiyuan Tian , Meng Zhang , Tian Qiu

The non-invasive spatiotemporal control of cellular functions, organization of tissues, and even the behavior of small animals has become paramount for advanced therapies. As magnetic fields do not interact with biological matter, their…

生物物理 · 物理学 2024-01-23 Peter Blümler , Fabian Raudzus , Friederike Schmid

This paper presents innovative designs for 3D-printed tumbling microrobots, specifically engineered for targeted in vivo drug delivery applications. The microrobot designs, created using stereolithography 3D printing technologies,…

For two decades, NdFeB based magnets have been a critical component in a range of electrical devices engaged in energy production and conversion. The magnet shape and the internal microstructure of the selected NdFeB grade govern their…

仪器与探测器 · 物理学 2016-11-17 J. Jacimovic , F. Binda , L. G. Herrmann , F. Greuter , J. Genta , M. Calvo , T. Tomse , R. A. Simon

We study different configurations of permanent magnets and ferromagnetic circuit, in order to optimize the magnetic field for the so-called ``magnetic tweezers'' technique, for studing mechanical properties of DNA molecules. The magnetic…

生物大分子 · 定量生物学 2009-07-28 Doriano Brogioli

In vitro investigation of neural architectures requires cell positioning. For that purpose, micro-magnets have been developed on silicon substrates and combined with chemical patterning to attract cells to adhesive sites and keep them there…

无序系统与神经网络 · 物理学 2015-06-23 Cécile Delacour , Ghislain Bugnicourt , Nora M Dempsey , Frédéric Dumas-Bouchiat , Catherine Villard

This paper introduces a new approach for simulating magnetic properties of nanocomposites comprising magnetic particles embedded in a non-magnetic matrix, taking into account the 3D structure of the system in which particles' positions…

介观与纳米尺度物理 · 物理学 2014-10-22 R. F. Neumann , M. Bahiana , L. G. Paterno , M. A. G. Soler , J. P. Sinnecker , J. G. Wen , P. C. Morais

A mathematical model is presented for predicting magnetic targeting of multifunctional carrier particles that are designed to deliver therapeutic agents to malignant tissue in vivo. These particles consist of a nonmagnetic core material…

生物物理 · 物理学 2015-06-26 E. J. Furlani , E. P. Furlani

We optimised the magnetic field homogeneity of two canonical designs for mobile microfluidic NMR applications: two parallel magnets with an air gap and a modified Halbach array. Along with the influence of the sample length, general design…

应用物理 · 物理学 2021-03-26 Yannick Klein , Leon Abelmann , Han Gardeniers

Systemic drug administration often causes off-target effects limiting the efficacy of advanced therapies. Targeted drug delivery approaches increase local drug concentrations at the diseased site while minimizing systemic drug exposure. We…

We demonstrate a straightforward approach to integrating a magnetic field into a low-temperature scanning tunneling microscope (STM) by adhering an NdFeB permanent magnet to a magnetizable sample plate. To render our magnet concept…

The recent demonstration that nanoparticles associated with various biological molecules and pharmacological agents can be administered systemically to humans, without toxicity from the particles, has opened a new era in the targeting of…

医学物理 · 物理学 2007-05-23 G. G. Kenning , R. Rodriguez , V. S. Zotev , A. Moslemi , S. Wilson , L. Hawel , C. Byus , J. S. Kovach

This paper introduces a novel second-order splitting scheme for charged-particle dynamics in strong magnetic fields characterized by the maximal ordering. The proposed scheme is explicit and symmetric, which respectively ensure the…

数值分析 · 数学 2026-04-14 Mengting Hu , Jiyong Li , Bin Wang

We demonstrate how micromagnetic simulations can be employed in order to characterize and analyze the magnetic microstructure of nanocomposites. For the example of nanocrystalline Nd$-$Fe$-$B, which is a potential material for future…

材料科学 · 物理学 2018-04-04 Sergey Erokhin , Dmitry Berkov , Masaaki Ito , Akira Kato , Masao Yano , Andreas Michels

A numerical model is developed for the motion of superparamagnetic nanoparticles in a non-Newtonian blood flow under the influence of a magnetic field. The rheological properties of blood are modeled by the Carreau flow and viscosity, and…

生物物理 · 物理学 2022-07-14 M. Lee , A. Shelke , S. Singh , J. Fan , P. Zaleski , S. Afkhami

The generation of localized magnetic field gradients by on-chip nanomagnets is important for a variety of technological applications, in particular for spin qubits. To advance beyond the empirical design of these nanomagnets, we propose a…

介观与纳米尺度物理 · 物理学 2024-04-10 William Legrand , Sandrine Lopes , Quentin Schaeverbeke , François Montaigne , Matthieu M. Desjardins

Multidimensional or multiplex bioanalysis represents a crucial approach to improve diagnostic precision, increase assay throughput and advance fundamental discoveries in analytical industry, life science and nanomedicine. Along this line,…

应用物理 · 物理学 2021-01-28 Gungun Lin

Penning traps are made extremely compact by embedding rare-earth permanent magnets in the electrode structure. Axially-oriented NdFeB magnets are used in unitary architectures that couple the electric and magnetic components into an…

仪器与探测器 · 物理学 2012-02-29 Joseph N. Tan , Samuel M. Brewer , Nicholas D. Guise

Magnetic fields interact with biological cells affecting them in variety of ways which are usually hard to predict. Among them, it was observed that strong fields can align dividing cells in a preferred direction. It was also demonstrated…

医学物理 · 物理学 2015-09-28 Stoyan Stoynev
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