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Photoacoustic (PA) imaging systems are spreading in the biomedical community, and the de-velopment of new PA contrast agents is an active area of research. However, PA contrast agents are usually characterized with spectrophotometry or…

Optoacoustic tomography (OAT) is a promising modality for breast cancer diagnosis because tumor angiogenesis and, potentially, hypoxia can be visualized using quantitative OAT (qOAT) techniques. Clinically meaningful inference generally…

医学物理 · 物理学 2025-10-02 Seonyeong Park , Gangwon Jeong , Umberto Villa , Mark A. Anastasio

Photoacoustic computed tomography (PACT) is a proven technology for imaging hemodynamics in deep brain of small animal models. PACT is inherently compatible with ultrasound (US) imaging, providing complementary contrast mechanisms. While…

Photoacoustic tomography is a hybrid imaging technique that combines high optical tissue contrast with high ultrasound resolution. Direct reconstruction methods such as filtered backprojection, time reversal and least squares suffer from…

Ultrasonic phased array technology, while versatile, often requires complex computing resources and numerous amplifier components. We present a Manually Reconfigurable Phased Array that physically controls transducer position and phase,…

应用物理 · 物理学 2025-05-22 Soma Mochizuki , Yoichi Ochiai , Tatsuki Fushimi

In this article, we are concerned with a nonlinear inverse problem with a forward operator involving an unknown function. The problem arises in diverse applications and is challenging in the presence of an unknown function, which makes it…

数值分析 · 数学 2023-02-07 Gyeongha Hwang , Gihyeon Jeon , Sunghwan Moon

Crosstalk represents a formidable obstacle in quantum computing. When quantum gates are executed parallelly, the resonance of qubit frequencies can lead to residual coupling, compromising the fidelity. Existing crosstalk solutions encounter…

量子物理 · 物理学 2024-10-10 Bin-han Lu , Peng Wang , Zhao-yun Chen , Huan-yu Liu , Tai-ping Sun , Peng Duan , Yu-chun Wu , Guo-ping Guo

In this work we present the first application of software-defined optoelectronics (SDO) for bidimensional optoacoustic tomography (OAT). The SDO concept refers to optoelectronic systems where the functionality associated with the…

信号处理 · 电气工程与系统科学 2023-05-10 Roberto Insabella , Martin Gonzalez , Lucas Riobo , Klaus Hass , Francisco Veiras

Passive acoustic mapping (PAM) is a promising tool for monitoring acoustic cavitation activities in the applications of ultrasound therapy. Data-adaptive beamformers for PAM have better image quality compared to the time exposure acoustics…

人工智能 · 计算机科学 2024-12-04 Yi Zeng , Jinwei Li , Hui Zhu , Shukuan Lu , Jianfeng Li , Xiran Cai

In most photoacoustic (PA) measurements, variations in speed-of-sound (SOS) of the subject are neglected under the assumption of acoustic homogeneity. Biological tissue with spatially heterogeneous SOS cannot be accurately reconstructed…

In an inhomogeneously illuminated photoacoustic image, important information like vascular geometry is not readily available when only the initial pressure is reconstructed. To obtain the desired information, algorithms for image…

图像与视频处理 · 电气工程与系统科学 2019-06-19 Yoeri E. Boink , Srirang Manohar , Christoph Brune

Photoacoustic imaging (PAI) has been applied to many biomedical applications over the past decades. However, the received PA signal usually suffers from poor signal-to-noise ratio (SNR). Conventional solution of employing higher-power…

信号处理 · 电气工程与系统科学 2023-07-26 Xinke Li , Peng Ge , Yuting Shen , Feng Gao , Fei Gao

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

医学物理 · 物理学 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

We present a new nonlinear optimization approach for the sparse reconstruction of single-photon absorption and two-photon absorption coefficients in photoacoustic tomography (PAT). This framework comprises of minimizing an objective…

最优化与控制 · 数学 2020-06-30 Madhu Gupta , Rohit Kumar Mishra , Souvik Roy

As a burgeoning medical imaging method based on hybrid fusion of light and ultrasound, photoacoustic imaging (PAI) has demonstrated high potential in various biomedical applications recently, especially in revealing the functional and…

信号处理 · 电气工程与系统科学 2022-11-21 Tianqu Hu , Zihao Huang , Peng Ge , Feng Gao , Fei Gao

Intracellular delivery of biomolecules remains a critical challenge in both basic cell biology and translational therapeutics. We introduce Programmable Acoustic Standing-wave Transfection (PAST), a microfluidic tool that leverages…

生物物理 · 物理学 2026-03-09 Subhas Nandy , Monica Manohar , Ashis K Sen

We study the inverse source problem in photoacoustic tomography (PAT) for mixed data, which denote a weighted linear combination of the acoustic pressure and its normal derivative on an observation surface. We consider in particular the…

偏微分方程分析 · 数学 2022-07-06 Florian Dreier , Markus Haltmeier

Photoacoustic computed tomography (PACT) is a rapidly emerging bioimaging modality that seeks to reconstruct an estimate of the absorbed optical energy density within an object. Conventional PACT image reconstruction methods assume a…

医学物理 · 物理学 2016-11-18 Chao Huang , Kun Wang , Robert W. Schoonover , Lihong V. Wang , Mark A. Anastasio

Quantitative Photoacoustic tomography (QPAT) is an emerging medical imaging modality which offers the possibility of combining the high resolution of the acoustic waves and large contrast of optical waves by quantifying the molecular…

数值分析 · 数学 2014-10-30 Adriano De Cezaro , Fabiana Travessini De Cezaro

Acoustic analogue computation and signal processing are of great significance, however, it's challenging to realize the acoustic computing devices because of their limitations of single function and complex structure. In this paper, an…

经典物理 · 物理学 2020-03-25 Jun Lan , Liwei Wang , Xiaowei Zhang , Minghui Lu , Xiaozhou Liu