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Bayesian Optimization (BO) is a popular framework for optimizing black-box functions. Despite its effectiveness, BO is often inefficient for high-dimensional problems due to the exponential growth of the search space, heterogeneity of the…

最优化与控制 · 数学 2026-05-08 Sourav Das , Debjani Chakraborty , Pabitra Mitra

Cancer remains a leading global health challenge and a major cause of mortality. This study leverages machine learning (ML) to predict the survivability of cancer patients with metastatic patterns using the comprehensive MSK-MET dataset,…

定量方法 · 定量生物学 2025-04-10 Polycarp Nalela , Deepthi Rao , Praveen Rao

Segmenting the boundary between tumor and healthy tissue during surgical cancer resection poses a significant challenge. In recent years, Hyperspectral Imaging (HSI) combined with Machine Learning (ML) has emerged as a promising solution.…

Bayesian optimisation is an adaptive sampling strategy for constructing a Gaussian process surrogate to efficiently search for the global minimum of a black-box computational model. Gaussian processes have limited applicability in…

应用统计 · 统计学 2025-12-04 Thomas A. Archbold , Ieva Kazlauskaite , Fehmi Cirak

The genomic profile underlying an individual tumor can be highly informative in the creation of a personalized cancer treatment strategy for a given patient; a practice known as precision oncology. This involves next generation sequencing…

The emerging field of precision oncology relies on the accurate pinpointing of alterations in the molecular profile of a tumor to provide personalized targeted treatments. Current methodologies in the field commonly include the application…

Glioblastoma (GBM) is the most common aggressive, fast-growing brain tumor, with a grim prognosis. Despite clinical diagnostic advancements, there have not been any substantial improvements to patient prognosis. Histopathological assessment…

计算机视觉与模式识别 · 计算机科学 2025-11-13 Sanyukta Adap , Ujjwal Baid , Spyridon Bakas

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

计算机视觉与模式识别 · 计算机科学 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Osteosarcoma (OS) is an aggressive primary bone malignancy. Accurate histopathological assessment of viable versus non-viable tumor regions after neoadjuvant chemotherapy is critical for prognosis and treatment planning, yet manual…

计算机视觉与模式识别 · 计算机科学 2026-01-15 Yaxi Chen , Zi Ye , Shaheer U. Saeed , Oliver Yu , Simin Ni , Jie Huang , Yipeng Hu

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

图像与视频处理 · 电气工程与系统科学 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

We propose small-variance asymptotic approximations for the inference of tumor heterogeneity (TH) using next-generation sequencing data. Understanding TH is an important and open research problem in biology. The lack of appropriate…

统计方法学 · 统计学 2015-11-17 Yanxun Xu , Peter Mueller , Yuan Yuan , Kamalakar Gulukota , Yuan Ji

The RSNA-MICCAI brain tumor radiogenomic classification challenge aimed to predict MGMT biomarker status in glioblastoma through binary classification on Multi parameter mpMRI scans: T1w, T1wCE, T2w and FLAIR. The dataset is splitted into…

图像与视频处理 · 电气工程与系统科学 2024-01-19 Amr Mohamed , Mahmoud Rabea , Aya Sameh , Ehab Kamal

Glioma is a common type of brain tumor, and accurate detection of it plays a vital role in the diagnosis and treatment process. Despite advances in medical image analyzing, accurate tumor segmentation in brain magnetic resonance (MR) images…

图像与视频处理 · 电气工程与系统科学 2020-02-27 Fateme Mostafaie , Reihaneh Teimouri , Zahra Nabizadeh , Nader Karimi , Shadrokh Samavi

Sample efficiency is one of the key factors when applying policy search to real-world problems. In recent years, Bayesian Optimization (BO) has become prominent in the field of robotics due to its sample efficiency and little prior…

机器人学 · 计算机科学 2020-11-19 Lukas P. Fröhlich , Melanie N. Zeilinger , Edgar D. Klenske

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

机器学习 · 计算机科学 2016-11-17 Chris Roadknight , Uwe Aickelin , Guoping Qiu , John Scholefield , Lindy Durrant

Glioblastomas are the most common malignant brain tumors in adults. Approximately 200000 people die each year from Glioblastoma in the world. Glioblastoma patients have a median survival of 12 months with optimal therapy and about 4 months…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Vikram Goddla

The segmentation of brain tumors in multimodal MRIs is one of the most challenging tasks in medical image analysis. The recent state of the art algorithms solving this task is based on machine learning approaches and deep learning in…

图像与视频处理 · 电气工程与系统科学 2020-02-11 Dmitrii Lachinov , Elena Shipunova , Vadim Turlapov

Bayesian optimization is an effective methodology for the global optimization of functions with expensive evaluations. It relies on querying a distribution over functions defined by a relatively cheap surrogate model. An accurate model for…

This paper proposes novel noise-free Bayesian optimization strategies that rely on a random exploration step to enhance the accuracy of Gaussian process surrogate models. The new algorithms retain the ease of implementation of the classical…

机器学习 · 计算机科学 2024-07-18 Hwanwoo Kim , Daniel Sanz-Alonso

Deep learning has quickly become the weapon of choice for brain lesion segmentation. However, few existing algorithms pre-configure any biological context of their chosen segmentation tissues, and instead rely on the neural network's…

计算机视觉与模式识别 · 计算机科学 2017-09-12 Andrew Beers , Ken Chang , James Brown , Emmett Sartor , CP Mammen , Elizabeth Gerstner , Bruce Rosen , Jayashree Kalpathy-Cramer
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