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The Dollo model for reconstructing evolutionary trees from binary characters has been proposed as a generalization of the infinite sites model, also known as the Perfect Phylogeny. In particular, the Dollo model is considered more realistic…

数据结构与算法 · 计算机科学 2025-06-17 Paola Bonizzoni , Gianluca Della Vedova , Mauricio Soto Gomez , Gabriella Trucco

The Persistent Perfect phylogeny, also known as Dollo-1, has been introduced as a generalization of the well-known perfect phylogenetic model for binary characters to deal with the potential loss of characters. The problem of deciding the…

数据结构与算法 · 计算机科学 2025-07-25 Paola Bonizzoni , Gianluca Della Vedova , Mauricio Soto Gomez , Gabriella Trucco

The so-called binary perfect phylogeny with persistent characters has recently been thoroughly studied in computational biology as it is less restrictive than the well known binary perfect phylogeny. Here, we focus on the notion of (binary)…

种群与进化 · 定量生物学 2020-03-30 Kristina Wicke , Mareike Fischer

Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for…

种群与进化 · 定量生物学 2016-08-10 Nikita Alexeev , Max A. Alekseyev

The perfect phylogeny is one of the most used models in different areas of computational biology. In this paper we consider the problem of the Persistent Perfect Phylogeny (referred as P-PP) recently introduced to extend the perfect…

数据结构与算法 · 计算机科学 2014-05-30 Paola Bonizzoni , Anna Paola Carrieri , Gianluca Della Vedova , Gabriella Trucco

Phylogenetic trees are used to model evolution: leaves are labelled to represent contemporary species ("taxa") and interior vertices represent extinct ancestors. Informally, convex characters are measurements on the contemporary species in…

组合数学 · 数学 2021-11-25 Steven Kelk , Ruben Meuwese , Stephan Wagner

One of the main aims of phylogenetics is the reconstruction of the correct evolutionary tree when data concerning the underlying species set are given. These data typically come in the form of DNA, RNA or protein alignments, which consist…

种群与进化 · 定量生物学 2019-03-22 Mareike Fischer

Phylogenetic (i.e. leaf-labeled) trees play a fundamental role in evolutionary research. A typical problem is to reconstruct such trees from data like DNA alignments (whose columns are often referred to as characters), and a simple…

种群与进化 · 定量生物学 2022-09-08 Mareike Fischer

Phylogenetic methods typically rely on an appropriate model of how data evolved in order to infer an accurate phylogenetic tree. For molecular data, standard statistical methods have provided an effective strategy for extracting…

种群与进化 · 定量生物学 2015-01-21 Robert W. Scotland , Mike Steel

The binary perfect phylogeny model is too restrictive to model biological events such as back mutations. In this paper we consider a natural generalization of the model that allows a special type of back mutation. We investigate the problem…

数据结构与算法 · 计算机科学 2012-06-29 Paola Bonizzoni , Chiara Braghin , Riccardo Dondi , Gabriella Trucco

Phylogenetic trees play a key role in the reconstruction of evolutionary relationships. Typically, they are derived from aligned sequence data (like DNA, RNA, or proteins) by using optimization criteria like, e.g., maximum parsimony (MP).…

种群与进化 · 定量生物学 2025-06-11 Mirko Wilde , Mareike Fischer

In conservation biology, phylogenetic diversity (PD) provides a way to quantify the impact of the current rapid extinction of species on the evolutionary `Tree of Life'. This approach recognises that extinction not only removes species but…

种群与进化 · 定量生物学 2022-04-13 Kerry Manson , Charles Semple , Mike Steel

In phylogenetic analysis, for non-molecular data, particularly morphology, parsimony optimization is the most commonly employed approach. In the past and present application of the parsimony principle, extra step numbers have been added…

种群与进化 · 定量生物学 2016-10-12 Yue Zhang

Finding the most parsimonious tree inside a phylogenetic network with respect to a given character is an NP-hard combinatorial optimization problem that for many network topologies is essentially inapproximable. In contrast, if the network…

种群与进化 · 定量生物学 2025-01-14 Martin Frohn , Steven Kelk

Applying a method to reconstruct a phylogenetic tree from random data provides a way to detect whether that method has an inherent bias towards certain tree `shapes'. For maximum parsimony, applied to a sequence of random 2-state data, each…

种群与进化 · 定量生物学 2014-06-03 Mareike Fischer , Michelle Galla , Lina Herbst , Mike Steel

In phylogenetics, a central problem is to infer the evolutionary relationships between a set of species $X$; these relationships are often depicted via a phylogenetic tree -- a tree having its leaves univocally labeled by elements of $X$…

数据结构与算法 · 计算机科学 2016-04-12 Julien Baste , Christophe Paul , Ignasi Sau , Celine Scornavacca

Estimating phylogenetic trees, which depict the relationships between different species, from aligned sequence data (such as DNA, RNA, or proteins) is one of the main aims of evolutionary biology. However, tree reconstruction criteria like…

种群与进化 · 定量生物学 2024-10-02 Mareike Fischer

Phylogenetic inference aims to reconstruct the evolutionary relationships of different species based on genetic (or other) data. Discrete characters are a particular type of data, which contain information on how the species should be…

种群与进化 · 定量生物学 2017-12-20 Magnus Bordewich , Ina Maria Deutschmann , Mareike Fischer , Elisa Kasbohm , Charles Semple , Mike Steel

One of the main aims of phylogenetics is to reconstruct the \enquote{Tree of Life}. In this respect, different methods and criteria are used to analyze DNA sequences of different species and to compare them in order to derive the…

种群与进化 · 定量生物学 2018-10-05 Michelle Galla , Kristina Wicke , Mareike Fischer

Lateral transfer, a process whereby species exchange evolutionary traits through non-ancestral relationships, is a frequent source of model misspecification in phylogenetic inference. Lateral transfer obscures the phylogenetic signal in the…

应用统计 · 统计学 2017-03-20 Luke J. Kelly , Geoff K. Nicholls
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