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This review focuses on the striking recent progress in solving for hydrophobic interactions between small inert molecules. We discuss several new understandings. Firstly, the _inverse _temperature phenomenology of hydrophobic interactions,…

化学物理 · 物理学 2016-04-27 L. R. Pratt , Mangesh I. Chaudhari , Susan B. Rempe

Hydrophobic interactions provide driving forces for protein folding, membrane formation, and oil-water separation. Motivated by information theory, the poorly understood nonpolar solute interactions in water are investigated. A simple…

chem-ph · 物理学 2008-02-03 G. Hummer , S. Garde , A. E. Garcia , A. Pohorille , L. R. Pratt

The aversion of hydrophobic solutes for water drives diverse interactions and assemblies across materials science, biology and beyond. % Here, we review the theoretical, computational and experimental developments which underpin a…

软凝聚态物质 · 物理学 2022-10-05 Nicholas B. Rego , Amish J. Patel

Hydrophobic interactions are central to biological self-assembly and soft matter organization, yet their microscopic origins remain debated. A key hallmark is the strengthening of attraction between hydrophobic solutes with increasing…

软凝聚态物质 · 物理学 2025-09-25 Nigel B. Wilding , Francesco Turci

The solvation of charged, nanometer-sized spherical solutes in water, and the effective, solvent-induced force between two such solutes are investigated by constant temperature and pressure Molecular Dynamics simulations of model solutes…

软凝聚态物质 · 物理学 2009-11-10 J. Dzubiella , J. -P. Hansen

The strength of hydrogen bonding in water is stronger than that of van der waals interaction, therefore water may play an important role in the process of hydrophobic effects. When a hydrophobic solute is dissolved into water, an interface…

化学物理 · 物理学 2017-03-08 Qiang Sun

The interactions of a hydrophilic surface with water can significantly influence the characteristics of the liquid water interface. In this manuscript, we explore this influence by studying the molecular structure of liquid water at a…

软凝聚态物质 · 物理学 2022-09-19 Sucheol Shin , Adam P. Willard

We present a probabilistic approach to water-water hydrogen bonding that allows one to obtain an analytic expression for the number of bonds per water molecule as a function of both its distance to a hydrophobic particle and hydrophobe…

软凝聚态物质 · 物理学 2013-03-20 Yuri S. Djikaev , Eli Ruckenstein

An understanding of the hydrophobicity of complex heterogeneous molecular assemblies is crucial to characterize and predict interactions between biomolecules. As such, uncovering the subtleties of assembly processes hinges on an accurate…

软凝聚态物质 · 物理学 2015-02-20 Richard C. Remsing , John D. Weeks

A theoretical model for the effect of water hydrogen bonding on the thermodynamics of hydrophobic hydration is proposed as a combination of the classical density functional theory with the recently developed probabilistic approach to water…

统计力学 · 物理学 2011-06-16 Yuri S. Djikaev

We use appropriately defined short ranged reference models of liquid water to clarify the different roles local hydrogen bonding, van der Waals attractions, and long ranged electrostatic interactions play in the solvation and association of…

统计力学 · 物理学 2015-02-20 Richard C. Remsing , John D. Weeks

The role of solute attractive forces on hydrophobic interactions is studied by coordinated development of theory and simulation results for Ar atoms in water. We present a concise derivation of the local molecular field (LMF) theory for the…

化学物理 · 物理学 2015-10-28 M. I. Chaudhari , S. B. Rempe , D. Asthagiri , L. Tan , L. R. Pratt

The fundamental role of hydrophobic interactions in nature and technology has motivated decades long research aimed at measuring the distance-dependent hydrophobic force and identifying its origin. This quest has nevertheless proved more…

软凝聚态物质 · 物理学 2016-03-29 Itai Schlesinger , Uri Sivan

In our recent works, based on the structural studies on water and interfacial water (topmost water layer at the solute/water interface), hydration free energy is derived and utilized to investigate the physical origin of hydrophobic…

化学物理 · 物理学 2018-11-14 Qiang Sun

Interfaces are a most common motif in complex systems. To understand how the presence of interfaces affect hydrophobic phenomena, we use molecular simulations and theory to study hydration of solutes at interfaces. The solutes range in size…

软凝聚态物质 · 物理学 2014-09-05 Amish J. Patel , Patrick Varilly , Sumanth N. Jamadagni , Hari Acharya , Shekhar Garde , David Chandler

Based on our recent study on physical origin of hydrophobic effects, this is applied to investigate the dependence of hydrophobic interactions on the solute size. As two same hydrophobic solutes are dissolved into water, the hydration free…

软凝聚态物质 · 物理学 2018-03-07 Qiang Sun

Hydration of hydrophobic solutes in water is the cause of different phenomena, including the hydrophobic heat-capacity anomaly, which are not yet fully understood. Because of its topicality, there has recently been growing interest in the…

软凝聚态物质 · 物理学 2009-11-10 Susanne Moelbert , Paolo De Los Rios

The hydrophobic interaction, often combined with the hydrophilic or ionic interactions, makes the behavior of aqueous solutions very rich and plays an important role in biological systems. Theoretical and computer simulation studies haven…

软凝聚态物质 · 物理学 2024-11-05 Hidefumi Naito , Tomonari Sumi , Kenichiro Koga

We investigate the curvature-dependence of water dynamics in the vicinity of hydrophobic spherical solutes using molecular dynamics simulations. For both, the lateral and perpendicular diffusivity as well as for H-bond kinetics of water in…

软凝聚态物质 · 物理学 2016-01-22 R. Gregor Weiß , Matthias Heyden , Joachim Dzubiella

With molecular simulation for water and a tunable hydrophobic substrate, we apply the instantaneous interface construction [A. P. Willard and D. Chandler, J. Phys. Chem. B, 114, 1954 (2010)] to examine the similarity between a water-vapor…

软凝聚态物质 · 物理学 2015-01-21 Adam P. Willard , David Chandler
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