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Clinical time series data are critical for patient monitoring and predictive modeling. These time series are typically multivariate and often comprise hundreds of heterogeneous features from different data sources. The grouping of features…

机器学习 · 计算机科学 2025-11-12 Fedor Sergeev , Manuel Burger , Polina Leshetkina , Vincent Fortuin , Gunnar Rätsch , Rita Kuznetsova

Commonly, clinical trials report effects not only for the full study population but also for patient subgroups. Meta-analyses of subgroup-specific effects and treatment-by-subgroup interactions may be inconsistent, especially when trials…

统计方法学 · 统计学 2025-12-23 Renato Panaro , Christian Röver , Tim Friede

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

种群与进化 · 定量生物学 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

The ability to train generative models that produce realistic, safe and useful tabular data is essential for data privacy, imputation, oversampling, explainability or simulation. However, generating tabular data is not straightforward due…

机器学习 · 计算机科学 2025-09-18 G. Charbel N. Kindji , Lina Maria Rojas-Barahona , Elisa Fromont , Tanguy Urvoy

Complex network data problems are increasingly common in many fields of application. Our motivation is drawn from strategic marketing studies monitoring customer choices of specific products, along with co-subscription networks encoding…

应用统计 · 统计学 2018-09-11 Daniele Durante , Sally Paganin , Bruno Scarpa , David B. Dunson

Evidence from animal models and epidemiological studies has linked prenatal alcohol exposure (PAE) to a broad range of long-term cognitive and behavioral deficits. However, there is virtually no information in the scientific literature…

When a subgroup is identified from the data, it must be evaluated in a replicable way. The usual in-sample approach, which evaluates the post-hoc identified subgroup as predefined, might suffer from selection bias. This issue of in-sample…

统计方法学 · 统计学 2026-05-06 Shuoxun Xu , Xinzhou Guo

Surrogate models are often used as computationally efficient approximations to complex simulation models, enabling tasks such as solving inverse problems, sensitivity analysis, and probabilistic forward predictions, which would otherwise be…

机器学习 · 统计学 2026-05-13 Philipp Reiser , Paul-Christian Bürkner , Anneli Guthke

In this work, we offer a thorough analytical investigation into the role of shared hyperparameters in a hierarchical Bayesian model, examining their impact on information borrowing and posterior inference. Our approach is rooted in a…

统计方法学 · 统计学 2025-09-23 Prasenjit Ghosh , Anirban Bhattacharya , Debdeep Pati

We introduce a framework for Bayesian experimental design (BED) with implicit models, where the data-generating distribution is intractable but sampling from it is still possible. In order to find optimal experimental designs for such…

机器学习 · 统计学 2021-05-11 Steven Kleinegesse , Michael U. Gutmann

We learn multiple hypotheses for related tasks under a latent hierarchical relationship between tasks. We exploit the intuition that for domain adaptation, we wish to share classifier structure, but for multitask learning, we wish to share…

机器学习 · 计算机科学 2014-08-12 Hal Daume

We learn multiple hypotheses for related tasks under a latent hierarchical relationship between tasks. We exploit the intuition that for domain adaptation, we wish to share classifier structure, but for multitask learning, we wish to share…

机器学习 · 计算机科学 2009-07-07 Hal Daumé

Consider the problem of imputing missing values in a dataset. One the one hand, conventional approaches using iterative imputation benefit from the simplicity and customizability of learning conditional distributions directly, but suffer…

机器学习 · 统计学 2022-06-17 Daniel Jarrett , Bogdan Cebere , Tennison Liu , Alicia Curth , Mihaela van der Schaar

An essential task of groups is to provide efficient solutions for the complex problems they face. Indeed, considerable efforts have been devoted to the question of collective decision-making related to problems involving a single dominant…

物理与社会 · 物理学 2017-04-05 Anna Zafeiris , Zsombor Koman , Enys Mones , Tamás Vicsek

Pattern formation in biological tissues plays an important role in the development of living organisms. Since the classical work of Alan Turing, a pre-eminent way of modelling has been through reaction-diffusion mechanisms. More recently,…

偏微分方程分析 · 数学 2023-01-27 Alexey Kazarnikov , Robert Scheichl , Heikki Haario , Anna Marciniak-Czochra

A common problem in Machine Learning and statistics consists in detecting whether the current sample in a stream of data belongs to the same distribution as previous ones, is an isolated outlier or inaugurates a new distribution of data. We…

机器学习 · 统计学 2018-05-16 Vincent Moens

The internal model principle, originally proposed in the theory of control of linear systems, nowadays represents a more general class of results in control theory and cybernetics. The central claim of these results is that, under suitable…

最优化与控制 · 数学 2025-04-22 Manuel Baltieri , Martin Biehl , Matteo Capucci , Nathaniel Virgo

Biological systems are often modelled at different levels of abstraction depending on the particular aims/resources of a study. Such different models often provide qualitatively concordant predictions over specific parametrisations, but it…

机器学习 · 统计学 2016-05-10 Giulio Caravagna , Luca Bortolussi , Guido Sanguinetti

Accurately capturing individual differences in semantic networks is fundamental to advancing our mechanistic understanding of semantic memory. Past empirical attempts to construct individual-level semantic networks from behavioral paradigms…

计算与语言 · 计算机科学 2024-10-25 Samuel Aeschbach , Rui Mata , Dirk U. Wulff

Natural data is often organized as a hierarchical composition of features. How many samples do generative models need in order to learn the composition rules, so as to produce a combinatorially large number of novel data? What signal in the…

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