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We propose a novel, succinct, and effective approach for distribution prediction to quantify uncertainty in machine learning. It incorporates adaptively flexible distribution prediction of $\mathbb{P}(\mathbf{y}|\mathbf{X}=x)$ in regression…

机器学习 · 计算机科学 2023-06-21 Xing Yan , Yonghua Su , Wenxuan Ma

Medical AI systems face catastrophic forgetting when deployed in clinical settings, where models must learn new imaging protocols while retaining prior diagnostic capabilities. This challenge is particularly acute for medical…

多媒体 · 计算机科学 2025-12-23 Ziyuan Gao , Philippe Morel

This paper presents DRE-CUSUM, an unsupervised density-ratio estimation (DRE) based approach to determine statistical changes in time-series data when no knowledge of the pre-and post-change distributions are available. The core idea behind…

机器学习 · 计算机科学 2022-01-28 Sudarshan Adiga , Ravi Tandon

Due to its ability to combine multiple base clusterings into a probably better and more robust clustering, the ensemble clustering technique has been attracting increasing attention in recent years. Despite the significant success, one…

机器学习 · 计算机科学 2020-01-01 Dong Huang , Chang-Dong Wang , Jian-Huang Lai

This paper presents a novel approach to binary classification using dynamic logistic ensemble models. The proposed method addresses the challenges posed by datasets containing inherent internal clusters that lack explicit feature-based…

机器学习 · 计算机科学 2024-12-02 Mohammad Zubair Khan , David Li

This paper develops a nonparametric model that represents how sequences of outcomes and treatment choices influence one another in a dynamic manner. In this setting, we are interested in identifying the average outcome for individuals in…

计量经济学 · 经济学 2019-01-16 Sukjin Han

We apply the "weighted ensemble" (WE) simulation strategy, previously employed in the context of molecular dynamics simulations, to a series of systems-biology models that range in complexity from one-dimensional to a system with 354…

分子网络 · 定量生物学 2015-03-11 Rory M. Donovan , Andrew J. Sedgewick , James R. Faeder , Daniel M. Zuckerman

Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE)…

统计方法学 · 统计学 2025-03-18 Runjia Li , Victor B. Talisa , Chung-Chou H. Chang

Linear mixed models are commonly used in analyzing stepped-wedge cluster randomized trials (SW-CRTs). A key consideration for analyzing a SW-CRT is accounting for the potentially complex correlation structure, which can be achieved by…

统计方法学 · 统计学 2024-08-21 Yongdong Ouyang , Monica Taljaard , Andrew B Forbes , Fan Li

We propose a flexible ensemble classification framework, Random Subspace Ensemble (RaSE), for sparse classification. In the RaSE algorithm, we aggregate many weak learners, where each weak learner is a base classifier trained in a subspace…

机器学习 · 统计学 2021-06-01 Ye Tian , Yang Feng

In recurrent survival analysis where the event of interest can occur multiple times for each subject, frailty models play a crucial role by capturing unobserved heterogeneity at the subject level within a population. Frailty models…

统计方法学 · 统计学 2024-10-30 Borna Bateni , Peyman Bateni , Bishwadeep Bhattacharyya , Devin Reeh

This paper presents an application of Generalized Estimating Equations (GEE) for analyzing age-specific death rates (ASDRs), constituting a longitudinal dataset with repeated measurements over time. GEE models, known for their robustness in…

应用统计 · 统计学 2024-01-24 Reza Dastranj , Martin Kolar

The intensive care units (ICUs) are responsible for generating a wealth of useful data in the form of Electronic Health Record (EHR). This data allows for the development of a prediction tool with perfect knowledge backing. We aimed to…

机器学习 · 计算机科学 2020-07-28 Saumil Maheshwari , Rohit Verma , Anupam Shukla , Ritu Tiwari , Rishu Garg

Estimating individualized treatment rules is a central task for personalized medicine. [zhao2012estimating] and [zhang2012robust] proposed outcome weighted learning to estimate individualized treatment rules directly through maximizing the…

统计方法学 · 统计学 2017-10-02 Yifan Cui , Ruoqing Zhu , Michael Kosorok

Motivated by fluorescence lifetime measurements this paper considers the problem of nonparametric density estimation in the pile-up model. Adaptive nonparametric estimators are proposed for the pile-up model in its simple form as well as in…

应用统计 · 统计学 2010-11-03 Fabienne Comte , Tabea Rebafka

Early identification of intensive care patients at risk of in-hospital mortality enables timely intervention and efficient resource allocation. Despite high predictive performance, existing machine learning approaches lack transparency and…

机器学习 · 计算机科学 2025-11-21 Alexander Bakumenko , Janine Hoelscher , Hudson Smith

Weighted ensemble (WE) is an enhanced path-sampling method that is conceptually simple, widely applicable, and statistically exact. In a WE simulation, an ensemble of trajectories is periodically pruned or replicated to enhance sampling of…

Hospitals lack automated systems to harness the growing volume of heterogeneous clinical and operational data to effectively forecast critical events. Early identification of patients at risk for deterioration is essential not only for…

Stepped wedge designs (SWDs) are increasingly used to evaluate longitudinal cluster-level interventions but pose substantial challenges for valid inference. Because crossover times are randomized, intervention effects are intrinsically…

统计方法学 · 统计学 2026-05-12 Fan Xia , K. C. Gary Chan , Emily Voldal , Avi Kenny , Patrick J. Heagerty , James P. Hughes

With known cause of death (CoD), competing risk survival methods are applicable in estimating disease-specific survival. Relative survival analysis may be used to estimate disease-specific survival when cause of death is either unknown or…

统计方法学 · 统计学 2021-12-10 Reuben Adatorwovor , Aurelien Latouche , Jason P. Fine