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Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

统计方法学 · 统计学 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

The outbreak of COVID-19 in 2020 has led to a surge in the interest in the mathematical modeling of infectious diseases. Disease transmission may be modeled as compartmental models, in which the population under study is divided into…

种群与进化 · 定量生物学 2020-10-27 Malú Grave , Alvaro L. G. A. Coutinho

Spatiotemporal modelling of infectious diseases such as COVID-19 involves using a variety of epidemiological metrics such as regional proportion of cases or regional positivity rates. Although observing their changes over time is critical…

Traditionally, the identification of parameters in the formulation and solution of inverse problems considers that models, variables and mathematical parameters are free of uncertainties. This aspect simplifies the estimation process, but…

种群与进化 · 定量生物学 2020-06-02 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt

This article shows how to specify and construct a discrete, stochastic, continuous-time model specifically for ecological systems. The model is more broad than typical chemical kinetics models in two ways. First, using time-dependent hazard…

种群与进化 · 定量生物学 2015-06-30 Andrew J. Dolgert

In this paper we consider a stochastic SEIQR (susceptible-exposed-infected-quarantined-recovered) epidemic model with a generalized incidence function. Using the Lyapunov method, we establish the existence and uniqueness of a global…

种群与进化 · 定量生物学 2025-01-31 Brahim Boukanjime , Mohamed Maama

We consider the modeling of the dynamics of the chemostat at its very source. The chemostat is classically represented as a system of ordinary differential equations. Our goal is to establish a stochastic model that is valid at the scale…

定量方法 · 定量生物学 2011-07-07 Fabien Campillo , Marc Joannides , Irène Larramendy

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

物理与社会 · 物理学 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

Large-scale testing is considered key to assess the state of the current COVID-19 pandemic. Yet, the link between the reported case numbers and the true state of the pandemic remains elusive. We develop mathematical models based on…

应用统计 · 统计学 2021-02-04 Michel Besserve , Simon Buchholz , Bernhard Schölkopf

In modern science, computer models are often used to understand complex phenomena, and a thriving statistical community has grown around analyzing them. This review aims to bring a spotlight to the growing prevalence of stochastic computer…

In this paper we propose a novel SEIR stochastic epidemic model. A distinguishing feature of this new model is that it allows us to consider a set up under general latency and infectious period distributions. To some extent, queuing systems…

Estimation of epidemiological and population parameters from molecular sequence data has become central to the understanding of infectious disease dynamics. Various models have been proposed to infer details of the dynamics that describe…

种群与进化 · 定量生物学 2014-12-25 Alex Popinga , Tim Vaughan , Tanja Stadler , Alexei Drummond

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

机器学习 · 统计学 2022-03-08 Swapneel Mehta , Noah Kasmanoff

I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach,…

机器学习 · 统计学 2026-01-09 James Rice

We present a tractable non-independent increment process which provides a high modeling flexibility. The process lies on an extension of the so-called Harris chains to continuous time being stationary and Feller. We exhibit constructions,…

应用统计 · 统计学 2016-05-19 Michelle Anzarut , Ramses H. Mena

The classical DICE model is a widely accepted integrated assessment model for the joint modeling of economic and climate systems, where all model state variables evolve over time deterministically. We reformulate and solve the DICE model as…

综合经济学 · 经济学 2024-12-13 Pavel V. Shevchenko , Daisuke Murakami , Tomoko Matsui , Tor A. Myrvoll

Global strategies to contain a pandemic, such as social distancing and protective measures, are designed to reduce the overall transmission rate between individuals. Despite such measures, essential institutions, including hospitals,…

种群与进化 · 定量生物学 2022-09-07 Roberto Morán-Tovar , Henning Gruell , Florian Klein , Michael Lässig

We present a simple dynamical model to address the question of introducing a stochastic nature in a time variable. This model includes noise in the time variable but not in the "space" variable, which is opposite to the normal description…

计算物理 · 物理学 2008-11-26 Toru Ohira

We tackle limitations of ordinary differential equation-driven Susceptible-Infections-Removed (SIR) models and their extensions that have recently be employed for epidemic nowcasting and forecasting. In particular, we deal with challenges…

统计计算 · 统计学 2026-02-10 Angelos Alexopoulos , Paul Birrell , Daniela De Angelis

The COVID-19 pandemic has highlighted delayed reporting as a significant impediment to effective disease surveillance and decision-making. In the absence of timely data, statistical models which account for delays can be adopted to nowcast…

应用统计 · 统计学 2020-11-19 Oliver Stoner , Theo Economou , Alba Halliday