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During the COVID-19 pandemic of 2019/2020, authorities have used temporary ad-hoc policy measures, such as lockdowns and mass quarantines, to slow its transmission. However, the consequences of widespread use of these unprecedented measures…

Models for control of epidemics on local, global and small-world networks are considered, with only partial information accessible about the status of individuals and their connections. The main goal of an effective control measure is to…

物理与社会 · 物理学 2007-05-23 A. Kleczkowski , B. Dybiec , C. A. Gilligan

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

种群与进化 · 定量生物学 2020-06-09 Evangelos Magirou

COVID-19, a viral respiratory pandemic, has rapidly spread throughout the globe. Large scale and rapid testing of the population is required to contain the disease, but such testing is prohibitive in terms of resources, cost and time.…

种群与进化 · 定量生物学 2020-07-21 Abhishek Srivastava , Anurag Mishra , Trusha Jayant Parekh , Sampreeti Jena

In this paper, we propose a dynamical model to describe the transmission of COVID-19, which is spreading in China and many other countries. To avoid a larger outbreak in the worldwide, Chinese government carried out a series of strong…

种群与进化 · 定量生物学 2020-03-09 Jiwei Jia , Jian Ding , Siyu Liu , Guidong Liao , Jingzhi Li , Ben Duan , Guoqing Wang , Ran Zhang

A simple, but ``classical``, stochastic model for epidemic spread in a finite, but large, population is studied. The progress of the epidemic can be divided into three different phases that requires different tools to analyse. Initially the…

种群与进化 · 定量生物学 2018-05-29 Åke Svensson

We propose and analyse an optimal control problem where the control system is a mathematical model for tuberculosis that considers reinfection. The control functions represent the fraction of early latent and persistent latent individuals…

最优化与控制 · 数学 2014-10-13 Paula Rodrigues , Cristiana J. Silva , Delfim F. M. Torres

As infectious disease outbreaks emerge, public health agencies often enact vaccination and social distancing measures to slow transmission. Their success depends on not only strategies and resources, but also public adherence. Individual…

物理与社会 · 物理学 2018-08-20 José L. Herrera , Lauren Ancel Meyers

The implementation of public policies is crucial in controlling the spread of COVID-19. However, the effectiveness of different policies can vary across different aspects of epidemic containment. Identifying the most effective policies is…

应用统计 · 统计学 2024-08-27 Zihan Wang

The COVID-19 pandemic has led to significant changes in how people are currently living their lives. To determine how to best reduce the effects of the pandemic and start reopening societies, governments have drawn insights from…

其他定量生物学 · 定量生物学 2020-09-08 Heather Z. Brooks , Unchitta Kanjanasaratool , Yacoub H. Kureh , Mason A. Porter

Contact tracing has been extensively studied from different perspectives in recent years. However, there is no clear indication of why this intervention has proven effective in some epidemics (SARS) and mostly ineffective in some others…

社会与信息网络 · 计算机科学 2021-03-01 Quyu Kong , Manuel Garcia-Herranz , Ivan Dotu , Manuel Cebrian

We study equilibrium distancing during epidemics. Distancing reduces the individual's probability of getting infected but comes at a cost. It creates a single-peaked epidemic, flattens the curve and decreases the size of the epidemic. We…

综合经济学 · 经济学 2021-03-02 Satoshi Fukuda , Nenad Kos , Christoph Wolf

A reasonable prediction of infectious diseases transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized…

种群与进化 · 定量生物学 2021-02-23 Yuxuan Zhang , Chen Gong , Dawei Li , Zhi-Wei Wang , Shengda D Pu , Alex W Robertson , Hong Yu , John Parrington

The emergence of coronavirus disease 2019 (COVID-19) in the United States has forced federal and local governments to implement containment measures. Moreover, the severity of the situation has sparked engagement by both the research and…

种群与进化 · 定量生物学 2020-07-03 Min Lu , Hemant Ishwaran

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent…

最优化与控制 · 数学 2015-05-06 Robin J. Evans , Musa Mammadov

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

种群与进化 · 定量生物学 2021-08-17 Evangelos F. Magirou

Research in epidemiology often focusses on designing interventions that result in the number of infected individuals asymptotically approaching zero, without considering that this number may peak at high values during transients. Recent…

最优化与控制 · 数学 2020-03-24 Willem Esterhuizen , Tim Aschenbruck , Jean Lévine , Stefan Streif

The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…

机器学习 · 计算机科学 2020-07-28 Rahul Singh , Fang Liu , Ness B. Shroff

Compartmental models are the most widely used framework for modeling infectious diseases. These models have been continuously refined to incorporate all the realistic mechanisms that can shape the course of an epidemic outbreak. Building on…