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We use X-ray phase-contrast tomography (XPCT) in a multi-organ approach to identify early imaging markers predictive of multiple sclerosis (MS) in EAE animal model. As the majority of neurodegenerative diseases, MS is characterized by a…

Medical time series (MedTS) data, such as Electroencephalography (EEG) and Electrocardiography (ECG), play a crucial role in healthcare, such as diagnosing brain and heart diseases. Existing methods for MedTS classification primarily rely…

信号处理 · 电气工程与系统科学 2024-10-22 Yihe Wang , Nan Huang , Taida Li , Yujun Yan , Xiang Zhang

Large pre-trained sentence encoders like BERT start a new chapter in natural language processing. A common practice to apply pre-trained BERT to sequence classification tasks (e.g., classification of sentences or sentence pairs) is by…

计算与语言 · 计算机科学 2020-02-26 Wenxuan Zhou , Junyi Du , Xiang Ren

Online medical forums have become a predominant platform for answering health-related information needs of consumers. However, with a significant rise in the number of queries and the limited availability of experts, it is necessary to…

Machine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by…

Stuttering is a complex speech disorder that can be identified by repetitions, prolongations of sounds, syllables or words, and blocks while speaking. Severity assessment is usually done by a speech therapist. While attempts at automated…

定量方法 · 定量生物学 2020-06-17 Sebastian P. Bayerl , Florian Hönig , Joelle Reister , Korbinian Riedhammer

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

音频与语音处理 · 电气工程与系统科学 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Electronic Health Records (EHR) offer rich real-world data for personalized medicine, providing insights into disease progression, treatment responses, and patient outcomes. However, their sparsity, heterogeneity, and high dimensionality…

统计方法学 · 统计学 2025-05-28 Linshanshan Wang , Mengyan Li , Zongqi Xia , Molei Liu , Tianxi Cai

The classification of clinical notes into specific diagnostic categories is critical in healthcare, especially for mental health conditions like Anxiety and Adjustment Disorder. In this study, we compare the performance of various…

Literature on machine learning for multiple sclerosis has primarily focused on the use of neuroimaging data such as magnetic resonance imaging and clinical laboratory tests for disease identification. However, studies have shown that these…

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

图像与视频处理 · 电气工程与系统科学 2022-01-07 Mehdi SadeghiBakhi , Hamidreza Pourreza , Hamidreza Mahyar

Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…

计算机视觉与模式识别 · 计算机科学 2017-09-04 Jie Zhang , Qingyang Li , Richard J. Caselli , Jieping Ye , Yalin Wang

Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…

图像与视频处理 · 电气工程与系统科学 2021-11-02 Moritz Platscher , Jonathan Zopes , Christian Federau

Segmentation is an important task in a wide range of computer vision applications, including medical image analysis. Recent years have seen an increase in the complexity of medical image segmentation approaches based on sophisticated…

图像与视频处理 · 电气工程与系统科学 2023-12-19 Tariq M Khan , Syed S. Naqvi , Erik Meijering

Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD,…

定量方法 · 定量生物学 2025-01-27 Roberto Goya-Maldonado , Tracy Erwin-Grabner , Ling-Li Zeng , Christopher R. K. Ching , Andre Aleman , Alyssa R. Amod , Zeynep Basgoze , Francesco Benedetti , Bianca Besteher , Katharina Brosch , Robin Bülow , Romain Colle , Colm G. Connolly , Emmanuelle Corruble , Baptiste Couvy-Duchesne , Kathryn Cullen , Udo Dannlowski , Christopher G. Davey , Annemiek Dols , Jan Ernsting , Jennifer W. Evans , Lukas Fisch , Paola Fuentes-Claramonte , Ali Saffet Gonul , Ian H. Gotlib , Hans J. Grabe , Nynke A. Groenewold , Dominik Grotegerd , Tim Hahn , J. Paul Hamilton , Laura K. M. Han , Ben J. Harrison , Tiffany C. Ho , Neda Jahanshad , Alec J. Jamieson , Andriana Karuk , Tilo Kircher , Bonnie Klimes-Dougan , Sheri-Michelle Koopowitz , Thomas Lancaster , Ramona Leenings , Meng Li , David E. J. Linden , Frank P. MacMaster , David M. A. Mehler , Susanne Meinert , Elisa Melloni , Bryon A. Mueller , Benson Mwangi , Igor Nenadić , Amar Ojha , Yasumasa Okamoto , Mardien L. Oudega , Brenda W. J. H. Penninx , Sara Poletti , Edith Pomarol-Clotet , Maria J. Portella , Elena Pozzi , Joaquim Radua , Elena Rodríguez-Cano , Matthew D. Sacchet , Raymond Salvador , Anouk Schrantee , Kang Sim , Jair C. Soares , Aleix Solanes , Dan J. Stein , Frederike Stein , Aleks Stolicyn , Sophia I. Thomopoulos , Yara J. Toenders , Aslihan Uyar-Demir , Eduard Vieta , Yolanda Vives-Gilabert , Henry Völzke , Martin Walter , Heather C. Whalley , Sarah Whittle , Nils Winter , Katharina Wittfeld , Margaret J. Wright , Mon-Ju Wu , Tony T. Yang , Carlos Zarate , Dick J. Veltman , Lianne Schmaal , Paul M. Thompson

Brain stroke has become a significant burden on global health and thus we need remedies and prevention strategies to overcome this challenge. For this, the immediate identification of stroke and risk stratification is the primary task for…

图像与视频处理 · 电气工程与系统科学 2025-01-07 Prantik Deb , Lalith Bharadwaj Baru , Kamalaker Dadi , Bapi Raju S

Post-traumatic stress disorder (PTSD) is a mental disorder that can be developed after witnessing or experiencing extremely traumatic events. PTSD can affect anyone, regardless of ethnicity, or culture. An estimated one in every eleven…

声音 · 计算机科学 2024-03-29 Mamadou Dia , Ghazaleh Khodabandelou , Alice Othmani

Multimodal schizophrenia assessment systems have gained traction over the last few years. This work introduces a schizophrenia assessment system to discern between prominent symptom classes of schizophrenia and predict an overall…

音频与语音处理 · 电气工程与系统科学 2024-11-19 Gowtham Premananth , Carol Espy-Wilson

Multiple Sclerosis (MS) is a disorder that usually appears in adults in their thirties. It has a prevalence that ranges between 2 and 150 per 100 000. Epidemiological studies of MS have provided hints on possible causes for the disease…

亚细胞过程 · 定量生物学 2013-08-23 Laura Facchini , Alberto Bellin , Eleuterio F. Toro

Background: Diabetic Sensorimotor polyneuropathy (DSPN) is a major long-term complication in diabetic patients associated with painful neuropathy, foot ulceration and amputation. The Michigan neuropathy screening instrument (MNSI) is one of…