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In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming…

计算机视觉与模式识别 · 计算机科学 2019-01-29 Yifan Peng , Shazia Dharssi , Qingyu Chen , Tiarnan D. Keenan , Elvira Agrón , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Age related macular degeneration (AMD) is one of the major causes for blindness in the elderly population. In this report, we propose deep learning based methods for retinal analysis using color fundus images for computer aided diagnosis of…

图像与视频处理 · 电气工程与系统科学 2020-09-04 Sharath M Shankaranarayana

Age-related Macular Degeneration (AMD) is a leading cause of blindness. Although the Age-Related Eye Disease Study group previously developed a 9-step AMD severity scale for manual classification of AMD severity from color fundus images,…

机器学习 · 计算机科学 2018-12-04 Qingyu Chen , Yifan Peng , Tiarnan Keenan , Shazia Dharssi , Elvira Agron , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…

图像与视频处理 · 电气工程与系统科学 2022-12-06 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

This work aims to research an automatic method for detecting Age-related Macular Degeneration (AMD) lesions in RGB eye fundus images. For this, we align invasively obtained eye fundus contrast images (the "golden standard" diagnostic) to…

图像与视频处理 · 电气工程与系统科学 2021-10-19 Rokas Pečiulis , Mantas Lukoševičius , Algimantas Kriščiukaitis , Robertas Petrolis , Dovilė Buteikienė

Background: Patients with neovascular age-related macular degeneration (AMD) can avoid vision loss via certain therapy. However, methods to predict the progression to neovascular age-related macular degeneration (nvAMD) are lacking.…

计算机视觉与模式识别 · 计算机科学 2019-04-12 Boris Babenko , Siva Balasubramanian , Katy E. Blumer , Greg S. Corrado , Lily Peng , Dale R. Webster , Naama Hammel , Avinash V. Varadarajan

By 2040, age-related macular degeneration (AMD) will affect approximately 288 million people worldwide. Identifying individuals at high risk of progression to late AMD, the sight-threatening stage, is critical for clinical actions,…

图像与视频处理 · 电气工程与系统科学 2020-07-21 Yifan Peng , Tiarnan D. Keenan , Qingyu Chen , Elvira Agrón , Alexis Allot , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color…

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

图像与视频处理 · 电气工程与系统科学 2023-08-31 Md. Aiyub Ali , Md. Shakhawat Hossain , Md. Kawar Hossain , Subhadra Soumi Sikder , Sharun Akter Khushbu , Mirajul Islam

A well-known retinal disease that sends blurry visions to the affected patients is Macular Degeneration. This research is based on classifying the healthy and macular degeneration fundus by localizing the affected region of the fundus. A…

图像与视频处理 · 电气工程与系统科学 2024-05-03 Tahmim Hossain , Sagor Chandro Bakchy

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

图像与视频处理 · 电气工程与系统科学 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…

计算机视觉与模式识别 · 计算机科学 2016-12-14 Arjun Raj Rajanna , Kamelia Aryafar , Rajeev Ramchandran , Christye Sisson , Ali Shokoufandeh , Raymond Ptucha

In recent years, there has been significant development in the analysis of medical data using machine learning. It is believed that the onset of Age-related Macular Degeneration (AMD) is associated with genetic polymorphisms. However,…

计算机视觉与模式识别 · 计算机科学 2024-09-18 Yoichi Furukawa , Satoshi Kamiya , Yoichi Sakurada , Kenji Kashiwagi , Kazuhiro Hotta

Age-related macular degeneration (AMD) is a major cause of blindness in older adults, severely affecting vision and quality of life. Despite advances in understanding AMD, the molecular factors driving the severity of subretinal scarring…

基因组学 · 定量生物学 2024-09-10 Kuan Yan , Yue Zeng , Dai Shi , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

Prognostic models aim to predict the future course of a disease or condition and are a vital component of personalized medicine. Statistical models make use of longitudinal data to capture the temporal aspect of disease progression;…

机器学习 · 计算机科学 2020-07-13 Joshua Bridge , Simon P. Harding , Yalin Zheng

Age-related macular degeneration (AMD) is one of the leading causes of irreversible vision impairment in people over the age of 60. This research focuses on semantic segmentation for AMD lesion detection in RGB fundus images, a non-invasive…

计算机视觉与模式识别 · 计算机科学 2025-10-31 Valentyna Starodub , Mantas Lukoševičius

In this manuscript, we automate the procedure of grading of diabetic retinopathy and macular edema from fundus images using an ensemble of convolutional neural networks. The availability of limited amount of labeled data to perform…

计算机视觉与模式识别 · 计算机科学 2018-09-13 Avinash Kori , Sai Saketh Chennamsetty , Mohammed Safwan K. P. , Varghese Alex

The identification and quantification of markers in medical images is critical for diagnosis, prognosis, and disease management. Supervised machine learning enables the detection and exploitation of findings that are known a priori after…

Fundus diseases are major causes of visual impairment and blindness worldwide, especially in underdeveloped regions, where the shortage of ophthalmologists hinders timely diagnosis. AI-assisted fundus image analysis has several advantages,…

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

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