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This paper combines a canonical epidemiology model of disease dynamics with government policy of lockdown and testing, and agents' decision to social distance in order to avoid getting infected. The model is calibrated with data on deaths…

综合经济学 · 经济学 2022-02-10 Shomak Chakrabarti , Ilia Krasikov , Rohit Lamba

Testing is a crucial control mechanism in the beginning phase of an epidemic when the vaccines are not yet available. It enables the public health authority to detect and isolate the infected cases from the population, thereby limiting the…

Many social programs attempt to allocate scarce resources to people with the greatest need. Indeed, public services increasingly use algorithmic risk assessments motivated by this goal. However, targeting the highest-need recipients often…

机器学习 · 计算机科学 2025-06-30 Bryan Wilder , Pim Welle

A key challenge in sequential decision making is optimizing systems safely under partial information. While much of the literature has focused on the cases of either partially known states or partially known dynamics, it is further…

最优化与控制 · 数学 2023-04-21 Qinyang He , Yonatan Mintz

In consequential domains, it is often impossible to compel individuals to take treatment, so that optimal policy rules are merely suggestions in the presence of human non-adherence to treatment recommendations. We study personalized…

机器学习 · 计算机科学 2026-04-24 Angela Zhou

Behavioral health interventions, delivered through digital platforms, have the potential to significantly improve health outcomes, through education, motivation, reminders, and outreach. We study the problem of optimizing personalized…

机器学习 · 计算机科学 2024-07-19 Jackie Baek , Justin J. Boutilier , Vivek F. Farias , Jonas Oddur Jonasson , Erez Yoeli

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

种群与进化 · 定量生物学 2021-08-17 Evangelos F. Magirou

The ongoing COVID-19 pandemic has overwhelmingly demonstrated the need to accurately evaluate the effects of implementing new or altering existing nonpharmaceutical interventions. Since these interventions applied at the societal level…

种群与进化 · 定量生物学 2021-01-27 Daniel K. Sewell , Aaron Miller

Providing accurate and reliable predictions about the future of an epidemic is an important problem for enabling informed public health decisions. Recent works have shown that leveraging data-driven solutions that utilize advances in deep…

机器学习 · 计算机科学 2023-11-21 Harshavardhan Kamarthi , B. Aditya Prakash

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

系统与控制 · 电气工程与系统科学 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shortening the interaction time between susceptible and infected…

种群与进化 · 定量生物学 2016-12-28 Bin Wu , Shanjun Mao , Jiazeng Wang , Da Zhou

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

物理与社会 · 物理学 2024-03-14 Joyce Luo , Bartolomeo Stellato

We study the problem of learning individualized dose intervals using observational data. There are very few previous works for policy learning with continuous treatment, and all of them focused on recommending an optimal dose rather than an…

统计方法学 · 统计学 2022-02-25 Guanhua Chen , Xiaomao Li , Menggang Yu

Since the first wave of the COVID-19 pandemic, governments have applied restrictions in order to slow down its spreading. However, creating such policies is hard, especially because the government needs to trade-off the spreading of the…

机器学习 · 计算机科学 2022-05-03 Leonardo Lucio Custode , Giovanni Iacca

Diverse non-pharmacological interventions (NPIs), serving as the primary approach for COVID-19 control prior to pharmaceutical interventions, showed heterogeneous spatiotemporal effects on pandemic management. Investigating the dynamic…

应用统计 · 统计学 2023-12-25 Binbin Lin , Yimin Dai , Lei Zou , Ning Ning

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

应用统计 · 统计学 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the…

物理与社会 · 物理学 2020-05-04 Harshad Khadilkar , Tanuja Ganu , Deva P Seetharam

The adoption of prophylaxis attitudes, such as social isolation and use of face masks, to mitigate epidemic outbreaks strongly depends on the support of the population. In this work, we investigate a susceptible-infected-recovered (SIR)…

物理与社会 · 物理学 2022-10-05 Diogo H. Silva , Celia Anteneodo , Silvio C. Ferreira

The rapid spread of the Coronavirus SARS-2 is a major challenge that led almost all governments worldwide to take drastic measures to respond to the tragedy. Chief among those measures is the massive lockdown of entire countries and cities,…

We study the optimal control problem of allocating campaigning resources over the campaign duration and degree classes in a social network. Information diffusion is modeled as a Susceptible-Infected epidemic and direct recruitment of…

社会与信息网络 · 计算机科学 2016-10-27 Kundan Kandhway , Joy Kuri