相关论文: Model-Based Reinforcement Learning for Type 1Diabe…

Patients with diabetes who are self-monitoring have to decide right before each meal how much insulin they should take. A standard bolus advisor exists, but has never actually been proven to be optimal in any sense. We challenged this rule…

Blood glucose simulation allows the effectiveness of type 1 diabetes (T1D) management strategies to be evaluated without patient harm. Deep learning algorithms provide a promising avenue for extending simulator capabilities; however, these…

Type 1 Diabetes (T1D) is an autoimmune disease leading to insulin insufficiency. Thus, patients require lifelong insulin therapy, which has a side effect of hypoglycemia. Hypoglycemia is a critical state of decreased blood glucose levels…

Type 1 diabetes mellitus (T1D) is characterized by insulin deficiency and blood glucose (BG) control issues. The state-of-the-art solution for continuous BG control is reinforcement learning (RL), where an agent can dynamically adjust…

Machine learning shows remarkable success for recognizing patterns in data. Here we apply the machine learning (ML) for the diagnosis of early stage diabetes, which is known as a challenging task in medicine. Blood glucose levels are…

Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…

People with type 1 diabetes (T1D) struggle to calculate the optimal insulin dose at mealtime, especially when under multiple daily injections (MDI) therapy. Effectively, they will not always perform rigorous and precise calculations, but…

To avoid serious diabetic complications, people with type 1 diabetes must keep their blood glucose levels (BGLs) as close to normal as possible. Insulin dosages and carbohydrate consumption are important considerations in managing BGLs.…

This article compares ten recently proposed neural networks and proposes two ensemble neural network-based models for blood glucose prediction. All of them are tested under the same dataset, preprocessing workflow, and tools using the…

The existing adaptive basal-bolus advisor (ABBA) was further developed to benefit patients under insulin therapy with multiple daily injections (MDI). Three different in silico experiments were conducted with the DMMS.R simulator to…

We consider the question of 30-minute prediction of blood glucose levels measured by continuous glucose monitoring devices, using clinical data. While most studies of this nature deal with one patient at a time, we take a certain percentage…

In this paper, a novel robust tracking control scheme for a general class of discrete-time nonlinear systems affected by unknown bounded uncertainty is presented. By solving a parameterized optimal tracking control problem subject to the…

Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…

Type 1 Diabetes (T1D) management is a complex task due to many variability factors. Artificial Pancreas (AP) systems have alleviated patient burden by automating insulin delivery through advanced control algorithms. However, the…

Type 2 Diabetes is a fast-growing, chronic metabolic disorder due to imbalanced insulin activity.The motion of this research is a comparative study of seven machine learning classifiers and an artificial neural network method to…

Progress in the biomedical field through the use of deep learning is hindered by the lack of interpretability of the models. In this paper, we study the RETAIN architecture for the forecasting of future glucose values for diabetic people.…

In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 diabetes. We consider three families of sequence models based on LSTM, GRU, and…

In this paper, models of the blood glucose (BG) dynamics in people with Type 1 diabetes (T1D) in response to moderate intensity aerobic activity are derived from physiology-based first principles and system identification experiments. We…

Accurately estimating parameters of physiological models is essential to achieving reliable digital twins. For Type 1 Diabetes, this is particularly challenging due to the complexity of glucose-insulin interactions. Traditional methods…