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Deep learning models have achieved expert-level performance in healthcare with an exclusive focus on training accurate models. However, in many clinical environments such as intensive care unit (ICU), real-time model serving is equally if…

机器学习 · 计算机科学 2020-08-11 Shenda Hong , Yanbo Xu , Alind Khare , Satria Priambada , Kevin Maher , Alaa Aljiffry , Jimeng Sun , Alexey Tumanov

Objectives. Accurately predicting transitions to anesthetic drugs overdosage is a critical challenge in general anesthesia as it requires the identification of EEG indicators relevant for anticipating the evolution of the depth of…

神经元与认知 · 定量生物学 2025-12-18 Christophe Sun , Pierre-Olivier Michel , François David , Nathalie Rouach , Dan Longrois , David Holcman

Real-world applications may be affected by outlying values. In the model-based clustering literature, several methodologies have been proposed to detect units that deviate from the majority of the data (rowwise outliers) and trim them from…

We propose a novel semiparametric model for the joint distribution of a continuous longitudinal outcome and the baseline covariates using an enriched Dirichlet process (EDP) prior. This joint model decomposes into a linear mixed model for…

统计方法学 · 统计学 2018-06-08 Bret Zeldow , James Flory , Alisa Stephens-Shields , Marsha Raebel , Jason Roy

Mixture model-based clustering, usually applied to multidimensional data, has become a popular approach in many data analysis problems, both for its good statistical properties and for the simplicity of implementation of the…

统计方法学 · 统计学 2013-12-30 Allou Samé , Faicel Chamroukhi , Gérard Govaert , Patrice Aknin

Machine learning (ML) models deployed in healthcare systems must face data drawn from continually evolving environments. However, researchers proposing such models typically evaluate them in a time-agnostic manner, splitting datasets…

机器学习 · 计算机科学 2023-07-21 Helen Zhou , Yuwen Chen , Zachary C. Lipton

Model-based clustering approaches concern the paradigm of exploratory data analysis relying on the finite mixture model to automatically find a latent structure governing observed data. They are one of the most popular and successful…

统计方法学 · 统计学 2014-04-29 Faicel Chamroukhi

The opioid epidemic, referring to the growing hospitalizations and deaths because of overdose of opioid usage and addiction, has become a severe health problem in the United States. Many strategies have been developed by the federal and…

计算与语言 · 计算机科学 2024-09-11 Yuchen Wang , Zhengyu Fang , Wei Du , Shuai Xu , Rong Xu , Jing Li

Contagion processes in social systems often involve interactions that go beyond pairwise contacts. Higher-order networks, represented as hypergraphs, have been widely used to model multi-body interactions, and their presence can drastically…

物理与社会 · 物理学 2026-01-26 Andrés Guzmán , Federico Malizia , István Z. Kiss

Background: Clinical trials are designed to prove the efficacy of an intervention by means of model-based approaches involving parametric hypothesis testing. Issues arise when no effect is observed in the study population. Indeed, an effect…

Accurate modeling of the patient flow within an Emergency Department (ED) is required by all studies dealing with the increasing and well-known problem of overcrowding. Since Discrete Event Simulation (DES) models are often adopted with the…

最优化与控制 · 数学 2021-02-02 A. De Santis , T. Giovannelli , S. Lucidi , M. Messedaglia , M. Roma

Minimizing response times to meet legal requirements and serve patients in a timely manner is crucial for Emergency Medical Service (EMS) systems. Achieving this goal necessitates optimizing operational decision-making to efficiently manage…

机器学习 · 计算机科学 2025-03-18 Maximiliane Rautenstrauß , Maximilian Schiffer

Problem definition: Access to accurate predictions of patients' outcomes can enhance medical staff's decision-making, which ultimately benefits all stakeholders in the hospitals. A large hospital network in the US has been collaborating…

The progression of chronic diseases often follows highly variable trajectories, and the underlying factors remain poorly understood. Standard mixed-effects models typically represent inter-patient differences as random deviations around a…

Time-to-event models are commonly used to study associations between risk factors and disease outcomes in the setting of electronic health records (EHR). In recent years, focus has intensified on social determinants of health, highlighting…

应用统计 · 统计学 2025-11-26 Yueming Shen , Christian Pean , David Dunson , Samuel Berchuck

Rapid naloxone delivery via drones offers a promising solution for responding to opioid overdose emergencies (OOEs), by extending lifesaving interventions to medically untrained bystanders before emergency medical services (EMS) arrive.…

计算机视觉与模式识别 · 计算机科学 2025-10-07 Shen Chang , Renran Tian , Nicole Adams , Nan Kong

Modern high-dimensional point process data, especially those from neuroscience experiments, often involve observations from multiple conditions and/or experiments. Networks of interactions corresponding to these conditions are expected to…

统计方法学 · 统计学 2021-09-27 Xu Wang , Ali Shojaie

This paper deals with the problem of clustering data returned by a radar sensor network that monitors a region where multiple moving targets are present. The network is formed by nodes with limited functionalities that transmit the…

信号处理 · 电气工程与系统科学 2024-05-07 Linjie Yan , Pia Addabbo , Nicomino Fiscante , Carmine Clemente , Chengpeng Hao , Gaetano Giunta , Danilo Orlando

The proliferation of early diagnostic technologies, including self-monitoring systems and wearables, coupled with the application of these technologies on large segments of healthy populations may significantly aggravate the problem of…

机器学习 · 计算机科学 2021-07-23 Anna Fedyukova , Douglas Pires , Daniel Capurro

The research explores the utilization of a deep learning model employing an attention mechanism in medical text mining. It targets the challenge of analyzing unstructured text information within medical data. This research seeks to enhance…

计算与语言 · 计算机科学 2024-06-04 Lingxi Xiao , Muqing Li , Yinqiu Feng , Meiqi Wang , Ziyi Zhu , Zexi Chen