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SARS-CoV-2 is a new human coronavirus (CoV), which emerged in China in late 2019 and is responsible for the global COVID-19 pandemic that caused more than 59 million infections and 1.4 million deaths in 11 months. Understanding the origin…

种群与进化 · 定量生物学 2020-11-26 Erwan Sallard , José Halloy , Didier Casane , Etienne Decroly , Jacques van Helden

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus of beta coronavirus genus originated in Wuhan, China in December 2019, resulted in the pandemic spread of Corona Virus Disease 2019 (COVID-19) worldwide. This genus…

组织与器官 · 定量生物学 2020-06-17 Mohammed A. El-Magd

There is a near consensus view that SARS-CoV-2 has a natural zoonotic origin; however, several characteristics of SARS-CoV-2 taken together are not easily explained by a natural zoonotic origin hypothesis. These include: a low rate of…

SARS-CoV is believed to originate from civets and was thought to have been eliminated as a threat after the 2003 outbreak. Here, we show that human SARS-CoV (huSARS-CoV) originated directly from bats, rather than civets, by a cross-species…

种群与进化 · 定量生物学 2013-05-15 Ailin Tao , Yuyi Huang , Peilu Li , Jun Liu , Nanshan Zhong , Chiyu Zhang

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus caused the novel coronavirus disease-2019 (COVID-19) affecting the whole world. Like SARS-CoV and MERS-CoV, SARS-CoV-2 are thought to originate in bats and then spread to…

其他定量生物学 · 定量生物学 2020-09-22 Daniel H. Tao , Weitao Sun

The ongoing global pandemic of infection disease COVID-19 caused by the 2019 novel coronavirus (SARS-COV-2, formerly 2019-nCoV) presents critical threats to public health and the economy since it was identified in China, December 2019. The…

基因组学 · 定量生物学 2020-06-02 Changchuan Yin

The COVID-19 pandemic is spreading rapidly around the world, causing countries to impose lockdowns and efforts to develop vaccines on a global scale. However, human-to-animal and animal-to-human transmission cannot be ignored, as severe…

种群与进化 · 定量生物学 2024-08-20 Zi Hian Tan , Kian Yan Yong , Jian-Jun Shu

The devastating impact of the COVID-19 pandemic caused by SARS coronavirus 2 (SARS CoV 2) has raised important questions about viral origin, mechanisms of zoonotic transfer to humans, whether companion or commercial animals can act as…

生物大分子 · 定量生物学 2021-07-12 Sakshi Piplani , Puneet Kumar Singh , David A. Winkler , Nikolai Petrovsky

The new coronavirus (2019-nCoV or SARS-CoV2), inducing the current pandemic disease (COVID-19) and causing pneumoniae in humans, is dramatically increasing in epidemic scale since its first appearance in Wuhan, China, in December 2019. The…

分子网络 · 定量生物学 2020-03-28 Maria Luisa Chiusano

The emerging global infectious COVID-19 coronavirus disease by novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and the economy since it was identified in late December…

基因组学 · 定量生物学 2020-03-25 Changchuan Yin

COVID-19, also known as Novel Coronavirus Disease, is a highly contagious disease that first surfaced in China in late 2019. SARS-CoV-2 is a coronavirus that belongs to the vast family of coronaviruses that causes this disease. The sickness…

图像与视频处理 · 电气工程与系统科学 2022-04-11 Narayana Darapaneni , Suma Maram , Harpreet Singh , Syed Subhani , Mandeep Kour , Sathish Nagam , Anwesh Reddy Paduri

Coronaviruses have recently caused world-wide severe outbreaks: SARS (Severe Acute Respiratory Syndrome) in 2002 and MERS (Middle-East Respiratory Syndrome) in 2012. At the end of 2019, a new coronavirus outbreak appeared in Wuhan (China)…

基因组学 · 定量生物学 2020-04-03 Miguel Ramos Pascual

After the detection of coronavirus disease 2019 (Covid-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, Hubei Province, China in late December, the cases of Covid-19 have spiralled out around the…

种群与进化 · 定量生物学 2022-10-12 Suman Bhowmick , Igor M. Sokolov , Hartmut H. K. Lentz

Metagenomic datasets from pangolin tissue specimens have previously yielded SARS-related coronaviruses which show high homology in their receptor binding domain to SARS-CoV-2, suggesting a potential zoonotic source for this feature of the…

基因组学 · 定量生物学 2022-03-02 Adrian Jones , Daoyu Zhang , Yuri Deigin , Steven C. Quay

In December 2019, a novel coronavirus (SARS-CoV-2) has been identified to cause acute respiratory disease in humans. An outbreak of this disease has been reported in mainland China with the city of Wuhan as the recognized epicenter. The…

种群与进化 · 定量生物学 2020-07-07 Jomar F. Rabajante

The only animals other than bats reported to have been infected with SARS-CoV-2-related coronaviruses (SARS2r-CoVs) prior to the COVID-19 pandemic are pangolins. In early 2020 multiple papers reported the identification of two clades of…

基因组学 · 定量生物学 2022-07-12 Adrian Jones , Steven E. Massey , Daoyu Zhang , Yuri Deigin , Steven C. Quay

COVID-19 is an emergent viral infection which rose in December 2019 in a city in the Chinese province of Hubei, Wuhan; the viral aetiology of this infection is now known as COVID-19 virus, which belongs to the Betacoronavirus genus. This…

种群与进化 · 定量生物学 2020-03-17 Alfonso Vivanco-Lira

Human civilization is experiencing a critical situation that presents itself for a new coronavirus disease 2019 (COVID-19). This virus emerged in late December 2019 in Wuhan city, Hubei, China. The grim fact of COVID-19 is, it is highly…

The recent zoonotic coronavirus virus outbreak of a novel type [COVID 19] has necessitated the adequate understanding of the evolutionary pathway of zoonotic viruses which adversely affects human populations for therapeutic constructs to…

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