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Purpose: Conventional automated segmentation of the head anatomy in MRI distinguishes different brain and non-brain tissues based on image intensities and prior tissue probability maps (TPM). This works well for normal head anatomies, but…

图像与视频处理 · 电气工程与系统科学 2021-05-20 Lukas Hirsch , Yu Huang , Lucas C Parra

Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

定量方法 · 定量生物学 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

Accurate and robust recording and decoding from the central nervous system (CNS) is essential for advances in human-machine interfacing. However, technologies used to directly measure CNS activity are limited by their resolution,…

神经元与认知 · 定量生物学 2025-09-19 Jaime Ibáñez , Blanka Zicher , Etienne Burdet , Stuart N. Baker , Carsten Mehring , Dario Farina

Deep convolutional neural networks (CNNs) have structures that are loosely related to that of the primate visual cortex. Surprisingly, when these networks are trained for object classification, the activity of their early, intermediate, and…

神经元与认知 · 定量生物学 2016-10-18 Omid Rezai , Pinar Boyraz Jentsch , Bryan Tripp

Normative models of brain structure estimate the effects of covariates such as age and sex using large samples of healthy controls. These models can then be applied to e.g. smaller clinical cohorts to distinguish disease effects from other…

Artificial intelligence has advanced rapidly in the last decade, driven primarily by progress in the scale of deep-learning systems. Despite these advances, the creation of intelligent systems that can operate effectively in diverse,…

人工智能 · 计算机科学 2024-12-25 Viviane Clay , Niels Leadholm , Jeff Hawkins

Understanding individual cortical development is essential for identifying deviations linked to neurodevelopmental disorders. However, current normative modelling frameworks struggle to capture fine-scale anatomical details due to their…

Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

机器学习 · 计算机科学 2016-12-06 Colin J Brown , Ghassan Hamarneh

With the wide adoption of functional magnetic resonance imaging (fMRI) by cognitive neuroscience researchers, large volumes of brain imaging data have been accumulated in recent years. Aggregating these data to derive scientific insights…

应用统计 · 统计学 2020-06-01 Ming Bo Cai , Michael Shvartsman , Anqi Wu , Hejia Zhang , Xia Zhu

Ex-vivo MRI offers invaluable insights into the complexity of the human brain, enabling high-resolution anatomical delineation and integration with histopathology, and thus, contributes to both basic and clinical studies on normal and…

定量方法 · 定量生物学 2024-12-25 Qinfeng Zhu , Sihui Li , Zuozhen Cao , Yao Shen , Haoan Xu , Guojun Xu , Haotian Li , Keqing Zhu , Zhiyong Zhao , Jing Zhang , Dan Wu

This volume is a collection of contributions from the 5th Workshop on Machine Learning and Interpretation in Neuroimaging (MLINI) at the Neural Information Processing Systems (NIPS 2015) conference. Modern multivariate statistical methods…

机器学习 · 统计学 2016-05-17 I. Rish , L. Wehbe , G. Langs , M. Grosse-Wentrup , B. Murphy , G. Cecchi

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the…

计算机视觉与模式识别 · 计算机科学 2026-05-14 Guangqian Yang , Tong Ding , Wenlong Hou , Yue Xun , Ye Du , Qian Niu , Shujun Wang

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

机器学习 · 计算机科学 2025-05-02 Eloy Geenjaar , Vince Calhoun

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

神经元与认知 · 定量生物学 2022-04-15 Sean Knight , Navjot Gadda

Most humans have the good fortune to live their lives embedded in richly structured social groups. Yet, it remains unclear how humans acquire knowledge about these social structures to successfully navigate social relationships. Here we…

神经元与认知 · 定量生物学 2019-04-23 Steven H. Tompson , Ari E. Kahn , Emily B. Falk , Jean M. Vettel , Danielle S. Bassett

In studying structural inter-connections in the human brain, it is common to first estimate fiber bundles connecting different regions of the brain relying on diffusion MRI. These fiber bundles act as highways for neural activity and…

应用统计 · 统计学 2016-12-06 Zhengwu Zhang , Maxime Descoteaux , David B. Dunson

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

计算机视觉与模式识别 · 计算机科学 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

Species detection is important for monitoring the health of ecosystems and identifying invasive species, serving a crucial role in guiding conservation efforts. Multimodal neural networks have seen increasing use for identifying species to…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Muchang Bahng , Charlie Berens , Jon Donnelly , Eric Chen , Chaofan Chen , Cynthia Rudin

Although modern imaging technologies allow us to study connectivity between two distinct brain regions in-vivo, an in-depth understanding of how anatomical structure supports brain function and how spontaneous functional fluctuations emerge…

神经元与认知 · 定量生物学 2024-10-29 Ziquan Wei , Tingting Dan , Jiaqi Ding , Guorong Wu

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

神经元与认知 · 定量生物学 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias