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Causal inference plays a fundamental role in various real-world applications. However, in the motivating non-small cell lung cancer (NSCLC) study, it is challenging to estimate the treatment effect of chemotherapy on circulating tumor DNA…

统计方法学 · 统计学 2025-08-25 Zhixin Qiu , Huichen Zhu , Wenjie Wang , Yanlin Tang

We consider a nonparametric Bayesian approach to estimate the diffusion coefficient of a stochastic differential equation given discrete time observations over a fixed time interval. As a prior on the diffusion coefficient, we employ a…

统计理论 · 数学 2020-07-22 Shota Gugushvili , Frank van der Meulen , Moritz Schauer , Peter Spreij

A general approach to selective inference is considered for hypothesis testing of the null hypothesis represented as an arbitrary shaped region in the parameter space of multivariate normal model. This approach is useful for hierarchical…

统计理论 · 数学 2018-03-28 Yoshikazu Terada , Hidetoshi Shimodaira

We address modelling and computational issues for multiple treatment effect inference under many potential confounders. Our main contribution is providing a trade-off between preventing the omission of relevant confounders, while not…

统计方法学 · 统计学 2025-02-04 Omiros Papaspiliopoulos , David Rossell , Miquel Torrens-i-Dinarès

Several epidemiological studies have provided evidence that long-term exposure to fine particulate matter (PM2.5) increases mortality risk. Furthermore, some population characteristics (e.g., age, race, and socioeconomic status) might play…

统计方法学 · 统计学 2023-11-01 Dafne Zorzetto , Falco J. Bargagli-Stoffi , Antonio Canale , Francesca Dominici

We propose a doubly robust approach to characterizing treatment effect heterogeneity in observational studies. We develop a frequentist inferential procedure that utilizes posterior distributions for both the propensity score and outcome…

统计方法学 · 统计学 2022-07-21 Heejun Shin , Joseph Antonelli

Proximal causal inference provides a framework for estimating the average treatment effect (ATE) in the presence of unmeasured confounding by leveraging outcome and treatment proxies. Identification in this framework relies on the existence…

统计方法学 · 统计学 2025-12-29 Chunrong Ai , Jiawei Shan

Graphical models are commonly used to discover associations within gene or protein networks for complex diseases such as cancer. Most existing methods estimate a single graph for a population, while in many cases, researchers are interested…

National statistical agencies are regularly required to produce estimates about various subpopulations, formed by demographic and/or geographic classifications, based on a limited number of samples. Traditional direct estimates computed…

统计方法学 · 统计学 2019-10-29 Shuchi Goyal , Gauri Sankar Datta , Abhyuday Mandal

We systematically investigate issues due to mis-specification that arise in estimating causal effects when (treatment) interference is informed by a network available pre-intervention, i.e., in situations where the outcome of a unit may…

统计方法学 · 统计学 2018-10-22 Vishesh Karwa , Edoardo M. Airoldi

Precision medicine is an emerging field that takes into account individual heterogeneity to inform better clinical practice. In clinical trials, the evaluation of treatment effect heterogeneity is an important component, and recently, many…

统计方法学 · 统计学 2023-02-24 Yuejia Xu , Angela M. Wood , Brian D. M. Tom

In cohort studies, non-random medication use can pose barriers to estimation of the natural history trend in a mean biomarker value (namely, the association between a predictor of interest and a biomarker outcome that would be observed in…

统计方法学 · 统计学 2021-01-25 Andrew J. Spieker , Joseph A. C. Delaney , Robyn L. McClelland

We present new insights into causal inference in the context of Heterogeneous Treatment Effects by proposing natural variants of Random Forests to estimate the key conditional distributions. To achieve this, we recast Breiman's original…

机器学习 · 统计学 2021-02-16 Qiming Du , Gérard Biau , François Petit , Raphaël Porcher

In observational studies, unmeasured confounders present a crucial challenge in accurately estimating desired causal effects. To calculate the hazard ratio (HR) in Cox proportional hazard models for time-to-event outcomes, two-stage…

Datasets in engineering applications are often limited and contaminated, mainly due to unavoidable measurement noise and signal distortion. Thus, using conventional data-driven approaches to build a reliable discriminative model, and…

机器学习 · 统计学 2020-04-14 Xihaier Luo , Ahsan Kareem

In this paper the estimation of the distribution function for potential outcomes to receiving or not receiving a treatment is studied. The approach is based on weighting observed data on the basis on estimated propensity score. A weighted…

统计方法学 · 统计学 2019-04-30 Pier Luigi Conti , Livia De Giovanni

Unobserved heterogeneous treatment effects have been emphasized in the recent policy evaluation literature (see e.g., Heckman and Vytlacil, 2005). This paper proposes a nonparametric test for unobserved heterogeneous treatment effects in a…

计量经济学 · 经济学 2021-08-17 Yu-Chin Hsu , Ta-Cheng Huang , Haiqing Xu

In this paper, we develop a multiply robust inference procedure of the average treatment effect (ATE) for data with high-dimensional covariates. We consider the case where it is difficult to correctly specify a single parametric model for…

统计方法学 · 统计学 2025-09-03 Xintao Xia , Yumou Qiu

This paper studies treatment effect models in which individuals are classified into unobserved groups based on heterogeneous treatment rules. Using a finite mixture approach, we propose a marginal treatment effect (MTE) framework in which…

计量经济学 · 经济学 2022-05-24 Tadao Hoshino , Takahide Yanagi

With the ubiquitous availability of unstructured data, growing attention is paid as how to adjust for selection bias in such non-probability samples. The majority of the robust estimators proposed by prior literature are either fully or…

统计方法学 · 统计学 2022-04-08 Ali Rafei , Michael R. Elliott , Carol A. C. Flannagan