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Meta-regression is often used to form hypotheses about what is associated with heterogeneity in a meta-analysis and to estimate the extent to which effects can vary between cohorts and other distinguishing factors. However, study-level…

统计方法学 · 统计学 2021-11-19 Maxwell Cairns , Luke A. Prendergast

Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is most commonly used. In this paper, we first illustrate with a simple example that the $I^2$ statistic is heavily…

统计方法学 · 统计学 2025-06-10 Ke Yang , Enxuan Lin , Wangli Xu , Liping Zhu , Tiejun Tong

The coefficient of variation (CV) is commonly used to measure relative dispersion. However, since it is based on the sample mean and standard deviation, outliers can adversely affect the CV. Additionally, for skewed distributions the mean…

Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is the most commonly used measure in the literature. In this paper, we show that the $I^2$ statistic was, in fact,…

统计方法学 · 统计学 2024-03-28 Ke Yang , Enxuan Lin , Tiejun Tong

In meta-analysis, the fraction of variance that is due to heterogeneity is known as I2. We show that the usual estimator of I2 is biased. The bias is largest when a meta-analysis has few studies and little heterogeneity. For example, with 7…

统计方法学 · 统计学 2017-03-24 Paul T. von Hippel

The coefficient of variation is a useful indicator for comparing the spread of values between dataset with different units or widely different means. In this paper we address the problem of investigating the equality of the coefficients of…

统计方法学 · 统计学 2023-06-06 Francesco Bertolino , Silvia Columbu , Mara Manca , Monica Musio

In this article, we consider the problem of constructing the confidence interval and testing hypothesis for the common coefficient of variation (CV) of several normal populations. A new method is suggested using the concepts of generalized…

统计理论 · 数学 2014-05-05 Javad Behboodian , Ali Akbar Jafari

This paper considers the problem of estimating the variance of a sum of a triangular array of random vectors with heterogeneous means. When random vectors exhibit two-way cluster dependence or weak dependence, standard variance estimators…

计量经济学 · 经济学 2026-03-13 Luther Yap

Control variates can be a powerful tool to reduce the variance of Monte Carlo estimators, but constructing effective control variates can be challenging when the number of samples is small. In this paper, we show that when a large number of…

统计方法学 · 统计学 2023-06-08 Zhuo Sun , Chris J. Oates , François-Xavier Briol

Cochran's $Q$ statistic is routinely used for testing heterogeneity in meta-analysis. Its expected value is also used for estimation of between-study variance $\tau^2$. Cochran's $Q$, or $Q_{IV}$, uses estimated inverse-variance weights…

统计方法学 · 统计学 2021-03-08 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

Random effects meta-analysis is a widely applied methodology to synthetize research findings of studies in a specific scientific question. Besides estimating the mean effect, an important aim of the meta-analysis is to summarize the…

应用统计 · 统计学 2026-01-28 Peter Matrai , Tamas Koi , Zoltan Sipos , Nelli Farkas

The paper presents a construction of a quantitative measure of variability for parameter estimates in the data fitting problem under interval uncertainty. It shows the degree of variability and ambiguity of the estimate, and the need for…

数值分析 · 数学 2020-03-12 Sergey P. Shary

Studies often estimate associations between an outcome and multiple variates. For example, studies of diagnostic test accuracy estimate sensitivity and specificity, and studies of predictive and prognostic factors typically estimate…

Researchers increasingly use meta-analysis to synthesize the results of several studies in order to estimate a common effect. When the outcome variable is continuous, standard meta-analytic approaches assume that the primary studies report…

Statistical inference about the average effect in random-effects meta-analysis has been considered insufficient in the presence of substantial between-study heterogeneity. Predictive distributions are well-suited for quantifying…

统计方法学 · 统计学 2025-10-16 David Kronthaler , Leonhard Held

Diversity indices are useful single-number metrics for characterizing a complex distribution of a set of attributes across a population of interest. The utility of these different metrics or sets of metrics depend on the context and…

种群与进化 · 定量生物学 2020-03-06 Song Xu , Lucas Böttcher , Tom Chou

The uncertainty or the variability of the data may be treated by considering, rather than a single value for each data, the interval of values in which it may fall. This paper studies the derivation of basic description statistics for…

统计计算 · 统计学 2008-12-18 Marie Chavent , Jérôme Saracco

Meta-analysis can be formulated as combining $p$-values across studies into a joint $p$-value function, from which point estimates and confidence intervals can be derived. We extend the meta-analytic estimation framework based on combined…

统计方法学 · 统计学 2025-10-21 David Kronthaler , Leonhard Held

The standardized mean difference (SMD) is a widely used measure of effect size, particularly common in psychology, clinical trials, and meta-analysis involving continuous outcomes. Traditionally, under the equal variance assumption, the SMD…

统计方法学 · 统计学 2025-06-05 Jiandong Shi , Xiaochen Zhang , Lu Lin , Hiu Yee Kwan , Tiejun Tong

Confidence intervals are a popular way to visualize and analyze data distributions. Unlike p-values, they can convey information both about statistical significance as well as effect size. However, very little work exists on applying…

应用统计 · 统计学 2017-01-23 Jussi Korpela , Emilia Oikarinen , Kai Puolamäki , Antti Ukkonen
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