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Bone pain typically occurs immediately following skeletal damage with mechanical distortion or rupture of nociceptive fibres. The pain mechanism is also associated with chronic pain conditions where the healing process is impaired. Any load…

Pressure ulcers are a severe disease affecting patients that are bedridden or in a wheelchair bound for long periods of time. These wounds can develop in the deep layers of the skin of specific parts of the body, mostly on heels or sacrum,…

The phase field fracture method has emerged as a promising computational tool for modelling a variety of problems including, since recently, hydrogen embrittlement and stress corrosion cracking. In this work, we demonstrate the potential of…

应用物理 · 物理学 2020-11-17 P. K. Kristensen , C. F. Niordson , E. Martínez-Pañeda

Metal rolling is a widespread and well-studied process, and many finite-element (FE) rolling simulations can be found in the scientific literature. However, these FE simulations are typically limited in their resolution of through-thickness…

Bioprinting is an enabling biofabrication technique to create heterogeneous tissue constructs according to patient-specific geometries and compositions. Optimization of bioinks as per requirements for specific tissue applications is a…

材料科学 · 物理学 2022-10-25 Abhinaba Banerjee , Sudipto Datta , Amit Roy Chowdhury , Pallab Datta

Studying psychiatric illness has often been limited by difficulties in connecting symptoms and behavior to neurobiology. Computational psychiatry approaches promise to bridge this gap by providing formal accounts of the latent information…

In this manuscript, we describe a scientific device specifically designed for the study of the plasticity fluctuations preceding the fracture of granular media. Biaxial tests on model granular media are performed using a commercial uniaxial…

软凝聚态物质 · 物理学 2024-03-15 Ambroise Mathey , Mickaël Le Fur , Patrick Chasle , Axelle Amon , Jérôme Crassous

Cell injection is a technique in the domain of biological cell micro-manipulation for the delivery of small volumes of samples into the suspended or adherent cells. It has been widely applied in various areas, such as gene injection,…

计算机科学中的逻辑 · 计算机科学 2017-03-21 Muhammad Usama Sardar , Osman Hasan

One of the goals of computer-aided surgery is to match intraoperative data to preoperative images of the anatomy and add complementary information that can facilitate the task of surgical navigation. In this context, mechanical palpation…

机器人学 · 计算机科学 2015-09-22 Elif Ayvali , Rangaprasad Arun Srivatsan , Long Wang , Rajarshi Roy , Nabil Simaan , Howie Choset

We investigate the approach to catastrophic failure in a model porous granular material undergoing uniaxial compression. A discrete element computational model is used to simulate both the micro-structure of the material and the complex…

无序系统与神经网络 · 物理学 2014-02-27 F. Kun , I. Varga , S. Lennartz-Sassinek , I. G. Main

This paper describes the use of the corotational cut Finite Element Method (FEM) for real-time surgical simulation. Users only need to provide a background mesh which is not necessarily conforming to the boundaries/interfaces of the…

计算工程、金融与科学 · 计算机科学 2018-11-20 Huu Phuoc Bui , Satyendra Tomar , Stéphane P. A. Bordas

To deal with permanent deformations and residual stresses, we consider a morphoelastic model for the scar formation as the result of wound healing after a skin trauma. Next to the mechanical components such as strain and displacements, the…

数值分析 · 数学 2022-03-17 Ginger Egberts , Fred Vermolen , Paul van Zuijlen

Fractured metal fragments with rough and irregular surfaces are often found at crime scenes. Current forensic practice visually inspects the complex jagged trajectory of fractured surfaces to recognize a ``match'' using comparative…

Understanding pain-related facial behaviors is essential for digital healthcare in terms of effective monitoring, assisted diagnostics, and treatment planning, particularly for patients unable to communicate verbally. Existing data-driven…

机器学习 · 计算机科学 2025-06-18 Zhiyu Wang , Yang Liu , Hatice Gunes

We study the elastic properties and mechanical stability of viral capsids under external force-loading with computer simulations. Our approach allows the implementation of specific geometries corresponding to specific phages such as…

材料科学 · 物理学 2009-11-13 Mathias Buenemann , Peter Lenz

Disorder and long-range interactions are two of the key components that make material failure an interesting playfield for the application of statistical mechanics. The cornerstone in this respect has been lattice models of the fracture in…

统计力学 · 物理学 2009-11-11 Mikko J. Alava , Phani K. V. V. Nukala , Stefano Zapperi

The paper proposes a method of damage detection in elastic materials, which is based on analyzing the time-dependent (dynamic) response of the material excited by an acoustic signal. A case study is presented consisting of experimental…

信号处理 · 电气工程与系统科学 2019-12-24 Michael Oberguggenberger , Martin Schwarz

This paper presents the design, characterization and validation of a wearable haptic device able to convey skin stretch, force feedback, and a combination of both, to the user's arm. In this work, we carried out physical and perceptual…

人机交互 · 计算机科学 2023-06-21 F. Barontini , M. G. Catalano , S. Fani , G. Grioli , M. Bianchi , A. Bicchi

The minimal invasive procedure of vertebroplasty is a surgical technique to treat compression fractures of vertebral bodies. During the treatment, liquid bone cement gets injected into the affected vertebral body and therein cures to a…

Mechanical stresses in soft materials across different length scales play a fundamental role in understanding the function of biological systems and in the use of artificial materials for engineering soft machines and biomedical devices.…

软凝聚态物质 · 物理学 2025-06-05 Zhaoyi Zhang , Guo-Yang Li , Yuxuan Jiang , Yang Zheng , Artur L. Gower , Michel Destrade , Yanping Cao