相关论文: Brain Connectomes Come of Age

Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Information flow provides a natural measure for the causal interaction between dynamical events. This study extends our previous rigorous formalism of componentwise information flow to the bulk information flow between two complex…

Distributed networks of brain areas interact with one another in a time-varying fashion to enable complex cognitive and sensorimotor functions. Here we use novel network analysis algorithms to test the recruitment and integration of…

This paper suggests a statistical framework for describing the relations between the physical and conceptual entities of a brain-like model. Features and concept instances are put into context, where the paper suggests that features may be…

Graphs are quickly emerging as a leading abstraction for the representation of data. One important application domain originates from an emerging discipline called "connectomics". Connectomics studies the brain as a graph; vertices…

It has been said that complexity lies between order and disorder. In the case of brain activity, and physiology in general, complexity issues are being considered with increased emphasis. We sought to identify features of brain organization…

Communication within or between complex systems is commonplace in the natural sciences and fields such as graph neural networks. The brain is a perfect example of such a complex system, where communication between brain regions is…

Neuroscience has long informed the development of artificial neural networks, but the success of modern architectures invites, in turn, the converse: can modern networks teach us lessons about brain function? Here, we examine the structure…

Current neuroimaging studies on neurodegenerative diseases and psychological risk factors have been developed predominantly in non Hispanic White cohorts, with other populations markedly underrepresented. In this work, we construct directed…

Dynamic functional connectivity, as measured by the time-varying covariance of neurological signals, is believed to play an important role in many aspects of cognition. While many methods have been proposed, reliably establishing the…

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

We present a continuous model for structural brain connectivity based on the Poisson point process. The model treats each streamline curve in a tractography as an observed event in connectome space, here a product space of cortical white…

Recent advances in experimental neuroscience allow, for the first time, non-invasive studies of the white matter tracts in the human central nervous system, thus making available cutting-edge brain anatomical data describing these global…

Here we describe an "information based exchange" model of brain function that ascribes to neocortex, basal ganglia, and thalamus distinct network functions. The model allows us to analyze whole brain system set point measures, such as the…

Computational modeling plays an increasingly important role in neuroscience, highlighting the philosophical question of how computational models explain. In the context of neural network models for neuroscience, concerns have been raised…

Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the…

At the inception of human brain mapping, two principles of functional anatomy underwrote most conceptions - and analyses - of distributed brain responses: namely functional segregation and integration. There are currently two main…

Higher-order networks encode the many-body interactions existing in complex systems, such as the brain, protein complexes, and social interactions. Simplicial complexes are higher-order networks that allow a comprehensive investigation of…

As the field of connectomics has matured, it has expanded from mapping the existence of connections between brain components to measuring the strength of connections. This information is increasingly accessible via methodologies such as…