相关论文: Brain Connectomes Come of Age

Artificial Intelligence (AI) systems based solely on neural networks or symbolic computation present a representational complexity challenge. While minimal representations can produce behavioral outputs like locomotion or simple…

As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

Technological advances have dramatically expanded our ability to probe multi-neuronal dynamics and connectivity in the brain. However, our ability to extract a simple conceptual understanding from complex data is increasingly hampered by…

The proliferation of multi-unit cortical recordings over the last two decades, especially in macaques and during motor-control tasks, has generated interest in neural "population dynamics": the time evolution of neural activity across a…

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Directionality is a fundamental feature of network connections. Most structural brain networks are intrinsically directed because of the nature of chemical synapses, which comprise most neuronal connections. Due to limitations of…

Propagation of oscillatory signals through the cortex and coherence is shaped by the connectivity structure of neuronal circuits. This study systematically investigates the network and stimulus properties that shape network responses. The…

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

The human brain network is modular--comprised of communities of tightly interconnected nodes. This network contains local hubs, which have many connections within their own communities, and connector hubs, which have connections diversely…

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Data produced by resting-state functional Magnetic Resonance Imaging are widely used to infer brain functional connectivity networks. Such networks correlate neural signals to connect brain regions, which consist in groups of dependent…

The function and dynamics of the cortex are fundamentally shaped by the specific wiring configurations of its constituent axonal fibers, also known as the connectome. However, many dynamical properties of macroscale cortical activity are…

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Large-scale neural mass models have been widely used to simulate resting-state brain activity from structural connectivity. In this work, we extend a well-established Wilson--Cowan framework by introducing a novel hemispheric-specific…

The exploration of brain networks has reached an important milestone as relatively large and reliable information has been gathered for connectomes of different species. Analyses of connectome data sets reveal that the structural length and…

To meet ongoing cognitive demands, the human brain must seamlessly transition from one brain state to another, in the process drawing on different cognitive systems. How does the brain's network of anatomical connections help facilitate…

A complete understanding of the brain requires an integrated description of the numerous scales of neural organization. It means studying the interplay of genes, synapses, and even whole brain regions which ultimately leads to different…

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Recent advances in neural recording technology allow simultaneously recording action potentials from hundreds to thousands of neurons in awake, behaving animals. However, characterizing spike patterns in the resulting data, and linking…

The study of connectivity and coordination has drawn increasing attention in recent decades due to their central role in driving markets, shaping societal dynamics, and influencing biological systems. Traditionally, observable connections,…