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Suppose, contrary to fact, in 1950, we had put the cohort of 18 year old non-smoking American men on a stringent mandatory diet that guaranteed that no one would ever weigh more than their baseline weight established at age 18. How would…

应用统计 · 统计学 2008-02-06 James Robins

This study describes the dynamics of COVID-19 deaths and infections via a Monte Carlo approach. The analyses include death's data from USA, Brazil, Mexico, UK, India and Russia, which comprise the four countries with the highest number of…

种群与进化 · 定量生物学 2021-01-04 Tulio Rodrigues , Otaviano Helene

Verbal autopsy (VA) algorithms are routinely used to determine individual-level causes of death (COD) in many low-and-middle-income countries, which are then aggregated to derive population-level cause-specific mortality fractions (CSMF),…

统计方法学 · 统计学 2023-12-07 Sandipan Pramanik , Scott Zeger , Dianna Blau , Abhirup Datta

Lung cancer continues to be the predominant cause of cancer-related mortality globally. This review analyzes various approaches, including advanced image processing methods, focusing on their efficacy in interpreting CT scans, chest…

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

机器学习 · 统计学 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

Correspondence Analysis analyzes two-way or multi-way tables withe each row and column becoming a point ion a multidimensional graphical map called biplot. It can be used to extract essential dimensions allowing simplification of the data…

应用统计 · 统计学 2020-02-27 Rena Sandy H. Baculinao , Roel F. Ceballos

Real-time monitoring in modern medical research introduces functional longitudinal data, characterized by continuous-time measurements of outcomes, treatments, and confounders. This complexity leads to uncountably infinite…

统计方法学 · 统计学 2025-08-15 Andrew Ying

In regions without complete-coverage civil registration and vital statistics systems there is uncertainty about even the most basic demographic indicators. In such areas the majority of deaths occur outside hospitals and are not recorded.…

Epidemiologists aiming to model the dynamics of global events face a significant challenge in identifying the factors linked with anomalies such as disease outbreaks. In this paper, we present a novel method for identifying the most…

机器学习 · 计算机科学 2021-09-20 Aboli Marathe , Saloni Parekh , Harsh Sakhrani

Recently, it has been shown that the transition rates of the illness-death model (IDM) for chronic conditions are related to the percentages of people in the states by a three-dimensional system of differential equations [Bri24]. The aim of…

应用统计 · 统计学 2025-02-05 Ralph Brinks

Ignoring the differences between countries, human reproductive and dispersal behaviors can be described by some standardized models, so whether there is a universal law of population growth hidden in the abundant and unstructured data from…

物理与社会 · 物理学 2024-02-08 Jiajun Ma , Qinghua Chen , Xiaosong Chen , Jingfang Fan , Xiaomeng Li , Yi Shi

We study the modeling and forecasting of high-dimensional functional time series, which can be temporally dependent and cross-sectionally correlated. We implement a functional analysis of variance (FANOVA) to decompose high-dimensional…

统计方法学 · 统计学 2026-03-31 Han Lin Shang , Cristian F. Jiménez-Varón

In statistics, forecast uncertainty is often quantified using a specified statistical model, though such approaches may be vulnerable to model misspecification, selection bias, and limited finite-sample validity. While bootstrapping can…

统计方法学 · 统计学 2026-03-12 Han Lin Shang

Most contemporary mortality models rely on extrapolating trends or past events. However, population dynamics will be significantly impacted by climate change, notably the influence of temperatures on mortality. In this paper, we introduce a…

应用统计 · 统计学 2025-02-04 Quentin Guibert , Gaëlle Pincemin , Frédéric Planchet

Worldwide, many millions of people die suddenly and unexpectedly each year, either with or without a prior history of cardiovascular disease. Such events are sparse (once in a lifetime), many victims will not have had prior investigations…

机器学习 · 计算机科学 2023-09-06 Yola Jones , Fani Deligianni , Jeff Dalton , Pierpaolo Pellicori , John G F Cleland

In the analysis of binary longitudinal data, it is of interest to model a dynamic relationship between a response and covariates as a function of time, while also investigating similar patterns of time-dependent interactions. We present a…

统计方法学 · 统计学 2023-04-11 Jinwon Sohn , Seonghyun Jeong , Young Min Cho , Taeyoung Park

When modeling sub-national mortality rates, we should consider three features: (1) how to incorporate any possible correlation among sub-populations to potentially improve forecast accuracy through multi-population joint modeling; (2) how…

统计方法学 · 统计学 2020-09-22 Han Lin Shang , Steven Haberman

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

定量方法 · 定量生物学 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

应用统计 · 统计学 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

Cancer data, particularly cancer incidence and mortality, are fundamental to understand the cancer burden, to set targets for cancer control and to evaluate the evolution of the implementation of a cancer control policy. However, the…

统计方法学 · 统计学 2025-11-27 Garazi Retegui , Jaione Etxeberria , María Dolores Ugarte