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Conventional lithography methods involving pattern transfer through resist templating face challenges of material compatibility with various process solvents. Other approaches of direct material writing often compromise pattern complexity…

材料科学 · 物理学 2024-07-19 Shuangshuang Zeng , Tian Tian , Jiwoo Oh , Chih-Jen Shih

The design of complex materials and the formation of specific patterns often arise from the properties of the individual building blocks. In this respect, colloidal systems offer a unique opportunity because nowadays they can be synthesized…

软凝聚态物质 · 物理学 2022-03-01 Fabrizio Camerin , Emanuela Zaccarelli

Wound infections are a significant clinical and socioeconomic challenge, contributing to delayed healing and increased wound chronicity. To enable early infection detection and inform therapeutic decisions, this study investigated the…

医学物理 · 物理学 2025-10-02 Jonathon Gorman , Charles Brooker , Xinyu Li , Giuseppe Tronci

The ability to resolve and quantify features at submicrometer scales from a single-shot image is crucial for real-time uncovering intricate structures in unlabeled biological samples and analyzing them at the subcellular level. We introduce…

光学 · 物理学 2025-01-22 Jaromír Běhal , Miroslav Ježek

Molecular assembly offers a promising path to detect life beyond Earth, while minimizing assumptions based on terrestrial life. As mass spectrometers will be central to upcoming Solar System missions, predicting molecular assembly from…

机器学习 · 计算机科学 2025-07-28 Lindsay A. Rutter , Abhishek Sharma , Ian Seet , David Obeh Alobo , An Goto , Leroy Cronin

We compute the precise elementary/composite field content of mass eigenstates in holographic duals of warped models in a slice of AdS_5. This is accomplished by decomposing the bulk fields not in the usual Kaluza-Klein basis, but rather…

高能物理 - 理论 · 物理学 2008-11-26 Brian Batell , Tony Gherghetta

In multi-resolution simulations, different system components are simultaneously modelled at different levels of resolution, these being smoothly coupled together. In the case of enzyme systems, computationally expensive atomistic detail is…

生物物理 · 物理学 2016-11-03 Aoife C. Fogarty , Raffaello Potestio , Kurt Kremer

Combined-resolution simulations are an effective way to study molecular properties across a range of length- and time-scales. These simulations can benefit from adaptive boundaries that allow the high-resolution region to adapt (change size…

计算物理 · 物理学 2018-05-09 Jason A. Wagoner , Vijay S. Pande

Digital holographic microcopy is a thriving imaging modality that attracts considerable research interest due to its ability to not only create excellent label-free contrast, but also supply valuable physical information regarding the…

光学 · 物理学 2019-04-01 Gili Dardikman , Natan T. Shaked

Fluorescence recovery after photobleaching (FRAP) measurements offer an important tool for analyzing diffusion and binding processes. Confocal scanning laser microscopes that are used in FRAP experiments bleach regions with a radially…

亚细胞过程 · 定量生物学 2009-03-09 George D Tsibidis

Tuning a very simple two-component holographic superfluid model, we can have a first order phase transition between two superfluid phases in the probe limit. Inspired by the potential landscape discussion, an intuitive physical picture for…

高能物理 - 理论 · 物理学 2020-09-21 Xin Li , Zhang-Yu Nie , Yu Tian

Sub-angstrom spatial resolution of electron density coupled with sub-femtosecond temporal resolution is required to directly observe the dynamics of the electronic structure of a molecule after photoinitiation or some other ultrafast…

We report efforts to quantify the loading of cell-sized lipid vesicles using in-line digital holographic microscopy. This method does not require fluorescent reporters, fluorescent tracers, or radioactive tracers. A single-color LED light…

We report on the development of Electron Holographic Tomography towards a versatile potential measurement technique, overcoming several limitations, such as a limited tilt range, previously hampering a reproducible and accurate…

材料科学 · 物理学 2015-06-22 A. Lubk , D. Wolf , P. Prete , N. Lovergine , T. Niermann , S. Sturm , H. Lichte

In spite of their ubiquitous applications, the characterization of glass fibers by means of all-optical techniques is still facing some limitations. Recently, X-ray absorption has been proposed as a method for visualizing the inner…

Stars form in the dense interiors of molecular clouds. The dynamics and physical properties of the atomic interstellar medium (ISM) set the conditions under which molecular clouds and eventually stars will form. It is, therefore, critical…

In the recent years, therapeutic use of antibodies has seen a huge growth, due to their inherent proprieties and technological advances in the methods used to study and characterize them. Effective design and engineering of antibodies for…

生物大分子 · 定量生物学 2020-05-08 Francesco Ambrosetti , Zuzana Jandova , Alexandre M. J. J. Bonvin

The characterisation of the physical properties of nanoparticles in their native environment plays a central role in a wide range of fields, from nanoparticle-enhanced drug delivery to environmental nanopollution assessment. Standard…

Broadband multimode squeezers constitute a powerful quantum resource with promising potential for different applications in quantum information technologies such as information coding in quantum communication networks or quantum simulations…

We demonstrate high-resolution non-iterative holographic coherent diffraction imaging with hard X-rays using a novel phase-shifting reference, fabricated by atomic layer deposition to produce nanosharp 3D structure. The method surpasses the…

介观与纳米尺度物理 · 物理学 2016-10-17 Mirna Saliba , Jeroen Bosgra , Christoph Rau , Christian David , Aaron D. Parsons , Ulrich H. Wagner , Pierre Thibault