相关论文: Brain volume: An important determinant of function…
Machine learning driven medical image segmentation has become standard in medical image analysis. However, deep learning models are prone to overconfident predictions. This has led to a renewed focus on calibrated predictions in the medical…
Accurate delineation of acute ischemic stroke lesions in MRI is a key component of stroke diagnosis and management. In recent years, deep learning models have been successfully applied to the automatic segmentation of such lesions. While…
Objective: We aimed to determine the relationship between day-to-day sleep efficiency variability and cognitive function among older adults using accelerometer data and three cognitive tests. Methods: Older adults aged 65+ with 5 days of…
There is a need to develop Monte Carlo simulations of stroke to run in-silico trials to replace animal models, explore clinical scenarios to develop hypotheses for clinical studies and for interpreting clinical monitoring. We perform…
In many medical applications, interpretable models with high prediction performance are sought. Often, those models are required to handle semi-structured data like tabular and image data. We show how to apply deep transformation models…
Brain atrophy is an important biomarker for monitoring neurodegeneration and disease progression in conditions such as multiple sclerosis (MS). An accurate and robust quantitative measurement of brain volume change is paramount for…
Assessing the quality of movements for post-stroke patients during the rehabilitation phase is vital given that there is no standard stroke rehabilitation plan for all the patients. In fact, it depends basically on the patient's functional…
We studied the performance of a robotic orthosis designed to assist the paretic hand after stroke. It is wearable and fully user-controlled, serving two possible roles: as a therapeutic tool that facilitates device mediated hand exercises…
Ischemic stroke is a common disease in the elderly population, which can cause long-term disability and even death. However, the time window for treatment of ischemic stroke in its acute stage is very short. To fast localize and…
Hypoxic Ischemic Encephalopathy (HIE) affects approximately 1-5/1000 newborns globally and leads to adverse neurocognitive outcomes in 30% to 50% of cases by two years of age. Despite therapeutic advances with Therapeutic Hypothermia (TH),…
Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…
Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…
Stroke is the second leading cause of death worldwide, and is increasingly prevalent in low- and middle-income countries (LMICs). Timely interventions can significantly influence stroke survivability and the quality of life after treatment.…
Classifying fine-grained ischemic stroke phenotypes relies on identifying important clinical information. Radiology reports provide relevant information with context to determine such phenotype information. We focus on stroke phenotypes…
The Women's Health Initiative randomized clinical trial of hormone therapy found no benefit of hormones in preventive cardiovascular disease, a finding in striking contrast with a large body of observational research. Understanding whether…
Acute stroke demands prompt diagnosis and treatment to achieve optimal patient outcomes. However, the intricate and irregular nature of clinical data associated with acute stroke, particularly blood pressure (BP) measurements, presents…
Radiologists use various imaging modalities to aid in different tasks like diagnosis of disease, lesion visualization, surgical planning and prognostic evaluation. Most of these tasks rely on the the accurate delineation of the anatomical…
The gold standard in the treatment of ischaemic stroke is set by evidence from randomized controlled trials, based on simple descriptions of presumptively homogeneous populations. Yet the manifest complexity of the brain's functional,…
Physical activity is a modifiable lifestyle factor with potential to support cognitive resilience. However, the association of moderate-to-vigorous physical activity (MVPA) intensity, and timing, with cognitive function and region-specific…
Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used…