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Populations evolving in fluctuating environments face the fundamental challenge of balancing adaptation to current conditions against preparation for uncertain futures. Here, we study microbial evolution in partially predictable…

种群与进化 · 定量生物学 2025-08-04 Roaa Mohmmed Yagb Omer , Onofrio Mazzarisi , Martina Dal Bello , Jacopo Grilli

The diffusion of particles in complex media has gained significant interest due to its dual relevance: probing the viscoelastic properties of materials via microrheology and assessing the extent of particle displacement over time. In this…

软凝聚态物质 · 物理学 2025-06-24 Fabian A. Garcia Daza , Alvaro Rodriguez-Rivas , Fernando Govantes , Alejandro Cuetos

Biofilms are complex, self-organized consortia of microorganisms that produce a functional, protective matrix of biomolecules. Physically, the structure of a biofilm can be described as an entangled polymer network which grows and changes…

生物物理 · 物理学 2016-11-08 Marco G. Mazza

A biofilm is a self-contained community of bacteria that uses signaling molecules called autoinducers (AIs) to coordinate responses through the process of quorum sensing. Biofilms exhibit a dual role that drives interest in both combating…

细胞行为 · 定量生物学 2025-11-07 Yanahan Paramalingam , Adam Noel

Microbes are everywhere, including in and on our bodies, and have been shown to play key roles in a variety of prevalent human diseases. Consequently, there has been intense interest in the design of bacteriotherapies or "bugs as drugs,"…

机器学习 · 统计学 2020-04-13 Travis E. Gibson , Georg K. Gerber

Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations…

生物物理 · 物理学 2019-06-19 Haoran Xu , Justas Dauparas , Debasish Das , Eric Lauga , Yilin Wu

Biological active materials such as bacterial biofilms and eukaryotic cells thrive in confined micro-spaces. Here, we show through numerical simulations that confinement can serve as a mechanical guidance to achieve distinct modes of…

软凝聚态物质 · 物理学 2019-08-05 Felix Kempf , Romain Mueller , Erwin Frey , Julia M. Yeomans , Amin Doostmohammadi

The problem of electing a unique leader is central to all distributed systems, including programmable matter systems where particles have constant size memory. In this paper, we present a silent self-stabilising, deterministic, stationary,…

分布式、并行与集群计算 · 计算机科学 2025-12-08 Jérémie Chalopin , Shantanu Das , Maria Kokkou

In many self-organising systems the ability to extract necessary resources from the external environment is essential to the system's growth and survival. Examples include the extraction of sunlight and nutrients in organic plants, of…

多智能体系统 · 计算机科学 2022-07-26 Payam Zahadat , Ada Diaconescu

Metagenomics has revealed hundreds of bacterial species in almost all microbiota. In a few well-studied cases, bacterial communities have been observed to coordinate their metabolic fluxes. In principle, bacteria can divide tasks to reap…

种群与进化 · 定量生物学 2016-04-12 Thibaud Taillefumier , Anna Posfai , Yigal Meir , Ned S. Wingreen

Natural Immune system plays a vital role in the survival of the all living being. It provides a mechanism to defend itself from external predates making it consistent systems, capable of adapting itself for survival incase of changes. The…

人工智能 · 计算机科学 2011-03-11 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

We review the computation models for biofilm and bacteria cells, providing perspectives on biofilm's various properties and potential serving as engineering living materials (ELMs), considering the omnipresence of such biological matter.…

生物物理 · 物理学 2022-06-09 Hanfeng Zhai

We explore the critical behaviors in the dynamics of information transfer of a biologically-inspired system by an individual-based model. "Quorum response", a type of social interaction which has been recognized taxonomically in animal…

物理与社会 · 物理学 2013-08-22 Collin Feng Hu

High-throughput experimental techniques and bioinformatics tools make it possible to obtain reconstructions of the metabolism of microbial species. Combined with mathematical frameworks such as flux balance analysis, which assumes that…

Many collective systems exist in nature far from equilibrium, ranging from cellular sheets up to flocks of birds. These systems reflect a form of active matter, whereby individual material components have internal energy. Under specific…

软凝聚态物质 · 物理学 2023-04-17 Namid R. Stillman , Silke Henkes , Roberto Mayor , Gilles Louppe

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

生物物理 · 物理学 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

Biomolecular machines transduce between different forms of energy. These machines make directed progress and increase their speed by consuming free energy, typically in the form of nonequilibrium chemical concentrations. Machine dynamics…

统计力学 · 物理学 2018-10-05 Aidan I Brown , David A Sivak

Bacterial growth models are commonly used for the prediction of microbial safety and the shelf life of perishable foods. Growth is affected by several environmental factors such as temperature, acidity level and salt concentration. In this…

应用统计 · 统计学 2014-11-24 A. Paula Palacios , J. Miguel Marín , Emiliano J. Quinto , Michael P. Wiper

Use of commercial growth chambers for study of biological processes involved in biomass growth and production pose certain limitations on the nature of studies that can be performed in them. Optimization of biomass rearing and production…

定量方法 · 定量生物学 2020-04-16 Murali Padmanabha , Stefan Streif

We address the question of optimization of the biomass long term productivity in the framework of microalgal biomass production in photobioreactors under the influence of day/night cycles. For that, we propose a simple bioreactor model…

最优化与控制 · 数学 2010-09-14 Frédéric Grognard , Andrei R. Akhmetzhanov , Masci Pierre , Olivier Bernard