相关论文: Adverse event enrichment tests using VAERS

Recently, the introduction of the generative adversarial network (GAN) and its variants has enabled the generation of realistic synthetic samples, which has been used for enlarging training sets. Previous work primarily focused on data…

This paper investigates the application of Feature-Enriched Generative Adversarial Networks (FE-GAN) in financial risk management, with a focus on improving the estimation of Value at Risk (VaR) and Expected Shortfall (ES). FE-GAN enhances…

Analyses of adverse events (AEs) are an important aspect of the evaluation of experimental therapies. The SAVVY (Survival analysis for AdVerse events with Varying follow-up times) project aims to improve the analyses of AE data in clinical…

The increased adoption of Electronic Health Records(EHRs) has brought changes to the way the patient care is carried out. The rich heterogeneous and temporal data space stored in EHRs can be leveraged by machine learning models to capture…

Adverse drug events (ADE) are prevalent and costly. Clinical trials are constrained in their ability to identify potential ADEs, motivating the development of spontaneous reporting systems for post-market surveillance. Statistical methods…

Many evolutionary algorithms (EAs) take advantage of parallel evaluation of candidates. However, if evaluation times vary significantly, many worker nodes (i.e.,\ compute clients) are idle much of the time, waiting for the next generation…

The SAVVY project aims to improve the analyses of adverse events (AEs) in clinical trials through the use of survival techniques appropriately dealing with varying follow-up times and competing events (CEs). This paper summarizes key…

Intraoperative adverse events (IAEs), such as bleeding or thermal injury, can lead to severe postoperative complications if undetected. However, their rarity results in highly imbalanced datasets, posing challenges for AI-based detection…

We present a graphical, knowledge-based method for reviewing treatment-emergent adverse events (AEs) in clinical trials. The approach enhances MedDRA by adding a hidden medical knowledge layer (Safeterm) that captures semantic relationships…

We combine two important ideas in the analysis of large-scale genomics experiments (e.g. experiments that aim to identify genes that are differentially expressed between two conditions). The first is use of Empirical Bayes (EB) methods to…

Inferring adverse events (AEs) of medical products from Spontaneous Reporting Systems (SRS) databases is a core challenge in contemporary pharmacovigilance. Bayesian methods for pharmacovigilance are attractive for their rigorous ability to…

Unlike conventional anomaly detection research that focuses on point anomalies, our goal is to detect anomalous collections of individual data points. In particular, we perform group anomaly detection (GAD) with an emphasis on irregular…

Despite the enormous performance of deepneural networks (DNNs), recent studies have shown theirvulnerability to adversarial examples (AEs), i.e., care-fully perturbed inputs designed to fool the targetedDNN. Currently, the literature is…

Deep learning (DL) has shown great success in many human-related tasks, which has led to its adoption in many computer vision based applications, such as security surveillance systems, autonomous vehicles and healthcare. Such…

The objective of our work is to demonstrate the feasibility of utilizing deep learning models to extract safety signals related to the use of dietary supplements (DS) in clinical text. Two tasks were performed in this study. For the named…

Measuring risk is at the center of modern financial risk management. As the world economy is becoming more complex and standard modeling assumptions are violated, the advanced artificial intelligence solutions may provide the right tools to…

It has been demonstrated that acoustic-emission (AE), inspection of structures can offer advantages over other types of monitoring techniques in the detection of damage; namely, an increased sensitivity to damage, as well as an ability to…

Deep neural networks (DNNs) have shown huge superiority over humans in image recognition, speech processing, autonomous vehicles and medical diagnosis. However, recent studies indicate that DNNs are vulnerable to adversarial examples (AEs),…

User attributes, such as gender and education, face severe incompleteness in social networks. In order to make this kind of valuable data usable for downstream tasks like user profiling and personalized recommendation, attribute inference…

Bayesian optimization is a widely used technique for optimizing black-box functions, with Expected Improvement (EI) being the most commonly utilized acquisition function in this domain. While EI is often viewed as distinct from other…