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This paper proposes a constrained control scheme for the control of the depth of hypnosis during induction phase in clinical anesthesia. In contrast with existing control schemes for propofol delivery, the proposed scheme guarantees…

系统与控制 · 计算机科学 2018-12-05 Mehdi Hosseinzadeh , Guy A. Dumont , Emanuele Garone

CT perfusion imaging (CTP) plays an important role in decision making for the treatment of acute ischemic stroke with large vessel occlusion. Since the CT perfusion scan time is approximately one minute, the patient is exposed to a…

医学物理 · 物理学 2021-11-04 Vojtěch Kulvait , Philip Hoelter , Arnd Doerfler , Georg Rose

The Internet of Medical Things (IoMT) offers a promising solution to improve patient health and reduce human error. Wearable smart infusion pumps that accurately administer medication and integrate with electronic health records are an…

密码学与安全 · 计算机科学 2023-12-14 Yas Vaseghi , Behnaz Behara , Mehdi Delrobaei

Studies of flow through the human airway have shown that inhalation time (IT) and secondary flow structures can play important roles in particle deposition. However, the effects of varying IT in conjunction with respiratory rate (RR) on…

流体动力学 · 物理学 2021-01-26 Manikantam G. Gaddam , Arvind Santhanakrishnan

Dose volume histograms are a useful tool in state-of-the-art radiotherapy planning, and it is essential to be aware of their limitations. Dose distributions computed by treatment planning systems are affected by several sources of…

医学物理 · 物理学 2007-06-13 Francisco Cutanda-Henriquez , Silvia Vargas-Castrillon

Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury. The purpose of this study was to assess the neuroprotective effect and the…

组织与器官 · 定量生物学 2007-08-15 A. Gonzalez-Falcon , E. Candelario-Jalil , M. Garcia-Cabrera , O. S. Leon

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

Compressible interfacial multiphase flows (CIMF) are essential to different applications, such as liquid fuel injection in supersonic propulsion systems. Since high-level details in CIMF are often difficult to measure in experiments,…

流体动力学 · 物理学 2023-11-16 Bo Zhang , Bradley Boyd , Yue Ling

This work examines the hypothesis that intravoxel incoherent motion MRI (IVIM) can quantify local cerebral blood flow (qCBF), infarct volume, and define the ischemic penumbra for determination of the perfusion-diffusion mismatch (PWI/DWI)…

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

医学物理 · 物理学 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Application of computation in many fields are growing fast in last two decades. Increasing on computation performance helps researchers to understand natural phenomena in many fields of science and technology including in life sciences.…

生物物理 · 物理学 2014-02-27 Suprijadi , Mohamad Rendi , Petrus Subekti , Sparisoma Viridi

Applications of large language models (LLMs) like ChatGPT have potential to enhance clinical decision support through conversational interfaces. However, challenges of human-algorithmic interaction and clinician trust are poorly understood.…

The objective was to determine the effect of pulse rate on the sensitivity to use interaural-time-difference (ITD) cues and to explore the mechanisms behind rate-dependent degradation in ITD perception in bilateral cochlear implant (CI)…

神经元与认知 · 定量生物学 2023-05-08 Hongmei Hu , Stephan Ewert , Birger Kollmeier , Deborah Vickers

Non-contact Tonometry (NCT) is a non-invasive ophthalmologic technique to measure intraocular pressure (IOP) using an air puff for routine glaucoma testing. Although IOP measurement using NCT has been perfected over many years, various…

医学物理 · 物理学 2023-09-18 Durbar Roy , Saptarshi Basu

We consider the fully-developed flow of an incompressible Newtonian fluid in a cylindrical vessel with elliptical cross-section (both an ellipse and the annulus between two confocal ellipses). In particular, we address an inverse problem,…

偏微分方程分析 · 数学 2013-01-01 Luigi C. Berselli , Francesca Guerra , Barbara Mazzolai , Edoardo Sinibaldi

We apply the lubrication approximation to solve for the flow generated by a peristaltic traveling wave in a finite, planar channel, and examine the effect of channel length. Cerebrospinal fluid (CSF) is hypothesized to be peristaltically…

流体动力学 · 物理学 2021-06-16 Jessica K Shang , J Brennen Carr , Caroline D Cardinale , Delin Zeng

Current approaches to in vivo imaging of the mouse central nervous system (CNS) do not offer a combination of micrometer resolution and a whole-brain field of view. To address this limitation, we introduce an approach based on synchrotron…

Intracranial aneurysms (IAs) are serious cerebrovascular lesions found in approximately 5\% of the general population. Their rupture may lead to high mortality. Current methods for assessing IA risk focus on morphological and…

Intracranial hemorrhage (ICH) is a critical medical emergency caused by the rupture of cerebral blood vessels, leading to internal bleeding within the skull. Accurate and timely classification of hemorrhage subtypes is essential for…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Mehdi Hosseini Chagahi , Md. Jalil Piran , Niloufar Delfan , Behzad Moshiri , Jaber Hatam Parikhan

Although Large Reasoning Models (LRMs) have progressed in solving complex problems, their chain-of-thought (CoT) reasoning often contains harmful content that can persist even when the final responses appear safe. We show that this issue…

人工智能 · 计算机科学 2026-03-03 Yichi Zhang , Yue Ding , Jingwen Yang , Tianwei Luo , Dongbai Li , Ranjie Duan , Qiang Liu , Hang Su , Yinpeng Dong , Jun Zhu