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In clinical or epidemiological follow-up studies, methods based on time scale indicators such as the restricted mean survival time (RMST) have been developed to some extent. Compared with traditional hazard rate indicator system methods,…

统计方法学 · 统计学 2022-05-26 Chengfeng Zhang , Hongji Wu , Baoyi Huang , Hao Yuan , Yawen Hou , Zheng Chen

The dynamics of a rain forest is extremely complex involving births, deaths and growth of trees with complex interactions between trees, animals, climate, and environment. We consider the patterns of recruits (new trees) and dead trees…

统计方法学 · 统计学 2024-09-19 Abdollah Jalilian , Francisco Cuevas-Pacheco , Ganggang Xu , Rasmus Waagepetersen

Environmental data may be "large" due to number of records, number of covariates, or both. Random forests has a reputation for good predictive performance when using many covariates with nonlinear relationships, whereas spatial regression,…

应用统计 · 统计学 2018-12-27 Eric W. Fox , Jay M. Ver Hoef , Anthony R. Olsen

An important task in survival analysis is choosing a structure for the relationship between covariates of interest and the time-to-event outcome. For example, the accelerated failure time (AFT) model structures each covariate effect as a…

统计方法学 · 统计学 2025-12-08 Harrison T. Reeder , Kyu Ha Lee , Sebastien Haneuse

The Cox regression model is a popular model for analyzing the relationship between a covariate and a survival endpoint. The standard Cox model assumes a constant covariate effect across the entire covariate domain. However, in many…

应用统计 · 统计学 2019-09-02 Sarit Agami , David M. Zucker , Donna Spiegelman

We use recurrent-events survival analysis techniques and methods to analyze the duration of Olympic records. The Kaplan-Meier estimator is used to perform preliminary tests and recurrent event survivor function estimators proposed by Wang &…

应用统计 · 统计学 2012-07-27 Elliott Hollifield , Victoria Trevino , Adam Zarn

The issue of estimating residual variance in regression models has experienced relatively little attention in the machine learning community. However, the estimate is of primary interest in many practical applications, e.g. as a primary…

统计理论 · 数学 2018-12-18 Burim Ramosaj , Markus Pauly

Interval-censored data, in which the event time is only known to lie in some time interval, arise commonly in practice; for example, in a medical study in which patients visit clinics or hospitals at pre-scheduled times, and the events of…

统计方法学 · 统计学 2017-07-21 Wei Fu , Jeffrey S. Simonoff

The limitations resulting from the dichtomisation of continuous outcomes have been extensively described. But the need to present results based on binary outcomes in particular in health science remains. Alternatives based on the…

统计方法学 · 统计学 2025-01-15 Odile Sauzet

Factorial survival designs with right-censored observations are commonly inferred by Cox regression and explained by means of hazard ratios. However, in case of non-proportional hazards, their interpretation can become cumbersome;…

统计方法学 · 统计学 2020-06-26 Marc Ditzhaus , Dennis Dobler , Markus Pauly

An accurate model of a patient's individual survival distribution can help determine the appropriate treatment for terminal patients. Unfortunately, risk scores (e.g., from Cox Proportional Hazard models) do not provide survival…

机器学习 · 计算机科学 2020-07-08 Humza Haider , Bret Hoehn , Sarah Davis , Russell Greiner

The difference in restricted mean survival time (RMST) is a clinically meaningful measure to quantify treatment effect in randomized controlled trials, especially when the proportional hazards assumption does not hold. Several frequentist…

Covariate adjustment is desired by both practitioners and regulators of randomized clinical trials because it improves precision for estimating treatment effects. However, covariate adjustment presents a particular challenge in…

统计方法学 · 统计学 2023-07-20 Yunfan Li , Jessica L. Ross , Aaron M. Smith , David P. Miller

This paper deals with the time-varying high dimensional covariance matrix estimation. We propose two covariance matrix estimators corresponding with a time-varying approximate factor model and a time-varying approximate characteristic-based…

计量经济学 · 经济学 2019-10-29 Jaeheon Jung

Survival trees are popular alternatives to Cox or Aalen regression models that offer both modelling flexibility and graphical interpretability. This paper introduces a new algorithm for survival trees that relaxes the assumption of…

统计方法学 · 统计学 2025-07-29 Pauline Baur , Markus Pauly , Takeshi Emura

The instability in the selection of models is a major concern with data sets containing a large number of covariates. This paper deals with variable selection methodology in the case of high-dimensional problems where the response variable…

应用统计 · 统计学 2012-03-23 Marie Walschaerts , Eve Leconte , Philippe Besse

The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

统计计算 · 统计学 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

The paper explores a different variation of combined regression strategy to calculate the conditional survival function. We use regression based weak learners to create the proposed ensemble technique. The proposed combined regression…

机器学习 · 计算机科学 2023-09-12 Rahul Goswami , Arabin Kr. Dey

Time-to-event endpoints are frequently used as outcomes in oncology and other disease areas where the outcome of interest may not be observed within a predetermined period. Although many analytical methods address the challenges of…

统计方法学 · 统计学 2026-04-14 Chen-Yen Lin , Susan Halabi , Taehwa Choi

Survival analysis is a widely used statistical framework for modeling time-to-event data under censoring. Classical methods, such as the Cox proportional hazards (Cox PH) model, offer a semiparametric approach to estimating the effects of…

机器学习 · 统计学 2026-04-23 Yang Xu , Wenbin Lu , Rui Song