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Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…

图像与视频处理 · 电气工程与系统科学 2025-06-03 Titus Griebel , Anwai Archit , Constantin Pape

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

计算机视觉与模式识别 · 计算机科学 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

Segmentation localizes objects in an image on a fine-grained per-pixel scale. Segmentation benefits by humans-in-the-loop to provide additional input of objects to segment using a combination of foreground or background clicks. Tasks…

计算机视觉与模式识别 · 计算机科学 2023-11-28 Nikolai Warner , Meera Hahn , Jonathan Huang , Irfan Essa , Vighnesh Birodkar

Development of deep learning systems for biomedical segmentation often requires access to expert-driven, manually annotated datasets. If more than a single expert is involved in the annotation of the same images, then the inter-expert…

Brain tumor segmentation is important for diagnosis of the tumor, and current deep-learning methods rely on a large set of annotated images for training, with high annotation costs. Unsupervised segmentation is promising to avoid human…

计算机视觉与模式识别 · 计算机科学 2025-01-28 Xiaochuan Ma , Jia Fu , Wenjun Liao , Shichuan Zhang , Guotai Wang

Obtaining a large amount of labeled data in medical imaging is laborious and time-consuming, especially for histopathology. However, it is much easier and cheaper to get unlabeled data from whole-slide images (WSIs). Semi-supervised…

图像与视频处理 · 电气工程与系统科学 2020-08-13 Zeyu Gao , Pargorn Puttapirat , Jiangbo Shi , Chen Li

Training neural networks using limited annotations is an important problem in the medical domain. Deep Neural Networks (DNNs) typically require large, annotated datasets to achieve acceptable performance which, in the medical domain, are…

计算机视觉与模式识别 · 计算机科学 2024-10-28 Bethany H. Thompson , Gaetano Di Caterina , Jeremy P. Voisey

Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…

计算机视觉与模式识别 · 计算机科学 2025-08-22 Xueyuan Li , Can Cui , Ruining Deng , Yucheng Tang , Quan Liu , Tianyuan Yao , Shunxing Bao , Naweed Chowdhury , Haichun Yang , Yuankai Huo

Nuclei detection is an important task in the histology domain as it is a main step toward further analysis such as cell counting, cell segmentation, study of cell connections, etc. This is a challenging task due to the complex texture of…

计算机视觉与模式识别 · 计算机科学 2018-08-28 Navid Alemi Koohababni , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

计算机视觉与模式识别 · 计算机科学 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

Nuclei Segmentation from histology images is a fundamental task in digital pathology analysis. However, deep-learning-based nuclei segmentation methods often suffer from limited annotations. This paper proposes a realistic data augmentation…

图像与视频处理 · 电气工程与系统科学 2022-07-01 Yi Lin , Zeyu Wang , Kwang-Ting Cheng , Hao Chen

In recent years, deep learning (DL) methods have become powerful tools for biomedical image segmentation. However, high annotation efforts and costs are commonly needed to acquire sufficient biomedical training data for DL models. To…

计算机视觉与模式识别 · 计算机科学 2018-06-05 Lin Yang , Yizhe Zhang , Zhuo Zhao , Hao Zheng , Peixian Liang , Michael T. C. Ying , Anil T. Ahuja , Danny Z. Chen

Automatic segmentation of microscopy images is an important task in medical image processing and analysis. Nucleus detection is an important example of this task. Mask-RCNN is a recently proposed state-of-the-art algorithm for object…

计算机视觉与模式识别 · 计算机科学 2021-04-01 Jeremiah W. Johnson

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

计算机视觉与模式识别 · 计算机科学 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Accurate medical image segmentation is essential for diagnosis, surgical planning and many other applications. Convolutional Neural Networks (CNNs) have become the state-of-the-art automatic segmentation methods. However, fully automatic…

The Pancreatic beta cell is an important target in diabetes research. For scalable modeling of beta cell ultrastructure, we investigate automatic segmentation of whole cell imaging data acquired through soft X-ray tomography. During the…

定量方法 · 定量生物学 2020-04-22 John Paul Francis , Hongzhi Wang , Kate White , Tanveer Syeda-Mahmood , Raymond Stevens

Semantic segmentation is the task of classifying each pixel in an image. Training a segmentation model achieves best results using annotated images, where each pixel is annotated with the corresponding class. When obtaining fine annotations…

计算机视觉与模式识别 · 计算机科学 2025-10-20 Jort de Jong , Mike Holenderski

Surgical tool segmentation in endoscopic images is an important problem: it is a crucial step towards full instrument pose estimation and it is used for integration of pre- and intra-operative images into the endoscopic view. While many…

计算机视觉与模式识别 · 计算机科学 2020-07-10 Daniil Pakhomov , Wei Shen , Nassir Navab

Intra-operative ultrasound is an increasingly important imaging modality in neurosurgery. However, manual interaction with imaging data during the procedures, for example to select landmarks or perform segmentation, is difficult and can be…

计算机视觉与模式识别 · 计算机科学 2019-04-19 Julia Rackerseder , Rüdiger Göbl , Nassir Navab , Christoph Hennersperger

Deep convolutional neural networks have driven substantial advancements in the automatic understanding of images. Requiring a large collection of images and their associated annotations is one of the main bottlenecks limiting the adoption…

计算机视觉与模式识别 · 计算机科学 2019-08-22 Zahra Mirikharaji , Yiqi Yan , Ghassan Hamarneh