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Digital pathology has recently been revolutionized by advancements in artificial intelligence, deep learning, and high-performance computing. With its advanced tools, digital pathology can help improve and speed up the diagnostic process,…

图像与视频处理 · 电气工程与系统科学 2024-03-28 Mohamed Elmanna , Ahmed Elsafty , Yomna Ahmed , Muhammad Rushdi , Ahmed Morsy

Interactive segmentation enables users to extract binary masks of target objects through simple interactions such as clicks, scribbles, and boxes. However, existing methods often support only limited interaction forms and struggle to…

计算机视觉与模式识别 · 计算机科学 2025-06-18 Xi Chen , Hengshuang Zhao

The superior performance of CNN on medical image analysis heavily depends on the annotation quality, such as the number of labeled image, the source of image, and the expert experience. The annotation requires great expertise and labour. To…

图像与视频处理 · 电气工程与系统科学 2021-04-06 Cheng Xue , Qiao Deng , Xiaomeng Li , Qi Dou , Pheng Ann Heng

The segmentation of cell nuclei in tissue images stained with the blood dye hematoxylin and eosin (H$\&$E) is essential for various clinical applications and analyses. Due to the complex characteristics of cellular morphology, a large…

图像与视频处理 · 电气工程与系统科学 2024-07-26 Ziwei Cui , Jingfeng Yao , Lunbin Zeng , Juan Yang , Wenyu Liu , Xinggang Wang

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep…

计算机视觉与模式识别 · 计算机科学 2020-06-25 Hyeonsoo Lee , Won-Ki Jeong

Point cloud semantic segmentation often requires largescale annotated training data, but clearly, point-wise labels are too tedious to prepare. While some recent methods propose to train a 3D network with small percentages of point labels,…

计算机视觉与模式识别 · 计算机科学 2021-11-24 Zhengzhe Liu , Xiaojuan Qi , Chi-Wing Fu

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

图像与视频处理 · 电气工程与系统科学 2024-07-18 Meilong Xu , Xiaoling Hu , Saumya Gupta , Shahira Abousamra , Chao Chen

Deep learning has revolutionized the accurate segmentation of diseases in medical imaging. However, achieving such results requires training with numerous manual voxel annotations. This requirement presents a challenge for whole-body…

图像与视频处理 · 电气工程与系统科学 2023-11-27 Matthias Hadlich , Zdravko Marinov , Moon Kim , Enrico Nasca , Jens Kleesiek , Rainer Stiefelhagen

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

计算机视觉与模式识别 · 计算机科学 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

Instance segmentation and classification of nuclei is an important task in computational pathology. We show that StarDist, a deep learning nuclei segmentation method originally developed for fluorescence microscopy, can be extended and…

计算机视觉与模式识别 · 计算机科学 2022-08-22 Martin Weigert , Uwe Schmidt

Classifying the various shapes and attributes of a glioma cell nucleus is crucial for diagnosis and understanding the disease. We investigate automated classification of glioma nuclear shapes and visual attributes using Convolutional Neural…

计算机视觉与模式识别 · 计算机科学 2017-01-11 Veda Murthy , Le Hou , Dimitris Samaras , Tahsin M. Kurc , Joel H. Saltz

Image based biomarker discovery typically requires an accurate segmentation of histologic structures (e.g., cell nuclei, tubules, epithelial regions) in digital pathology Whole Slide Images (WSI). Unfortunately, annotating each structure of…

图像与视频处理 · 电气工程与系统科学 2021-01-07 Runtian Miao , Robert Toth , Yu Zhou , Anant Madabhushi , Andrew Janowczyk

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

计算机视觉与模式识别 · 计算机科学 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

计算机视觉与模式识别 · 计算机科学 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Automatic medical image segmentation via convolutional neural networks (CNNs) has shown promising results. However, they may not always be robust enough for clinical use. Sub-optimal segmentation would require clinician's to manually…

图像与视频处理 · 电气工程与系统科学 2021-10-26 Helena Williams , João Pedrosa , Laura Cattani , Susanne Housmans , Tom Vercauteren , Jan Deprest , Jan D'hooge

Interactive segmentation uses real-time user inputs, such as mouse clicks, to iteratively refine model predictions. Although not originally designed to address distribution shifts, this paradigm naturally lends itself to such challenges. In…

计算机视觉与模式识别 · 计算机科学 2026-04-22 Wentian Xu , Ziyun Liang , Harry Anthony , Yasin Ibrahim , Felix Cohen , Guang Yang , Konstantinos Kamnitsas

Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an…

图像与视频处理 · 电气工程与系统科学 2021-01-01 Lu Wang , Dong Guo , Guotai Wang , Shaoting Zhang

Nuclei appear small in size, yet, in real clinical practice, the global spatial information and correlation of the color or brightness contrast between nuclei and background, have been considered a crucial component for accurate nuclei…

图像与视频处理 · 电气工程与系统科学 2023-07-18 Zhenqi He , Mathias Unberath , Jing Ke , Yiqing Shen

Annotation cost is a bottleneck for collecting massive data in mammography, especially for training deep neural networks. In this paper, we study the use of heterogeneous levels of annotation granularity to improve predictive performances.…

图像与视频处理 · 电气工程与系统科学 2019-09-13 Thi-Lam-Thuy Le , Nicolas Thome , Sylvain Bernard , Vincent Bismuth , Fanny Patoureaux