相关论文: Reduction of a model for sodium exchanges in kidne…
The growing importance of real-time simulation in the medical field has exposed the limitations and bottlenecks inherent in the digital representation of complex biological systems. This paper presents a novel methodology aimed at advancing…
In equilibrium and supercooled liquids, polymorphism is manifested by thermodynamic regions defined in the phase diagram, which are predominantly of different short- and medium-range order (local structure). It is found that on the phase…
We revisit the classical problem of flow of electrolyte solutions through charged capillary nanopores or nanotubes as described by the capillary pore model (also called "space charge" theory). This theory assumes very long and thin pores…
Here we describe an "information based exchange" model of brain function that ascribes to neocortex, basal ganglia, and thalamus distinct network functions. The model allows us to analyze whole brain system set point measures, such as the…
Predicting the asymmetric structure and dynamics of solvated hydroxide and hydronium in water has been a challenging task from ab initio molecular dynamics (AIMD). The difficulty mainly comes from a lack of accurate and efficient…
The flow of ions through permeable channels causes voltage drop in physiological nanodomains such as synapses, dendrites and dendritic spines, and other protrusions. How the voltage changes around channels in these nanodomains has remained…
Kidney exchange programs (KEPs) form an innovative approach to increasing the donor pool through allowing the participation of renal patients together with a willing but incompatible donor. The aim of a KEP is to identify groups of…
We review modeling of astrocyte ion dynamics with a specific focus on the implications of so-called spatial potassium buffering, where excess potassium in the extracellular space (ECS) is transported away to prevent pathological neural…
Carrier injection into carbon nanotubes and graphene nanoribbons, contacted by a metal coating over an arbitrary length, is studied by various means: Minimal models allow for exact analytic solutions which can be transferred to the original…
In this paper we study a semilinear hyperbolic-parabolic system as a model for some chemotaxis phenomena evolving on networks; we consider transmission conditions at the inner nodes which preserve the fluxes and non- homogeneous boundary…
The diffusive transport of biased Brownian particles in a two-dimensional symmetric channel is investigated numerically considering both the no-flow and the reflection boundary conditions at the channel boundaries. Here, the geometrical…
The mass and momentum balances are theoretically studied in heterogeneous two-component systems. Following Gibbs the system is presented as two bulk and a single surface phases. Comparing the equations derived with some typical rheological…
Background: Large foundation models have revolutionized single-cell analysis, yet no kidney-specific model currently exists, and it remains unclear whether organ-focused models can outperform generalized models. The kidney's complex…
We study a diffuse interface model for the flow of two viscous incompressible Newtonian fluids in a bounded domain. The fluids are assumed to be macroscopically immiscible, but a partial mixing in a small interfacial region is assumed in…
We have studied the planetary nebula (PN) NGC 6572 through 3D morpho-kinematic and photoionization modelling. The 3D morphology is reconstructed from the Hubble Space Telescope images in different narrow band filters and position-velocity…
Kinetic aspects of the ion current layer at the center of a reconnection outflow exhaust near the X-type region are investigated by a two-dimensional particle-in-cell (PIC) simulation. The layer consists of magnetized electrons and…
We study non-linear rheology of a simple theoretical model developed to mimic layered systems such as lamellar structures under shear. In the present work we study a 2-dimensional version of the model which exhibits a Kosterlitz-Thouless…
To overcome incompatibility issues, kidney patients may swap their donors. In international kidney exchange programmes (IKEPs), countries merge their national patient-donor pools. We consider a recently introduced credit system. In each…
Metallic open cell foams have multiple applications in industry, e. g. as catalyst supports in chemical processes. Their regular or heterogeneous microscopic structure determines the macroscopic thermodynamic and chemical properties. We…
Exchange of biochemical substances is essential way in establishing communication between bacterial cells. It is noticeable that all phases of the process are heavily influenced by perturbations of either internal or external parameters.…