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Top-down instance segmentation framework has shown its superiority in object detection compared to the bottom-up framework. While it is efficient in addressing over-segmentation, top-down instance segmentation suffers from over-crop…

计算机视觉与模式识别 · 计算机科学 2022-11-04 Qilong Zhangli , Jingru Yi , Di Liu , Xiaoxiao He , Zhaoyang Xia , Qi Chang , Ligong Han , Yunhe Gao , Song Wen , Haiming Tang , He Wang , Mu Zhou , Dimitris Metaxas

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

图像与视频处理 · 电气工程与系统科学 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

Whole slide imaging (WSI) is an emerging technology for digital pathology. The process of autofocusing is the main influence of the performance of WSI. Traditional autofocusing methods either are time-consuming due to repetitive mechanical…

图像与视频处理 · 电气工程与系统科学 2020-03-17 Qiang Li , Xianming Liu , Kaige Han , Cheng Guo , Xiangyang Ji , Xiaolin Wu

The whole slide histopathology images (WSIs) play a critical role in gastric cancer diagnosis. However, due to the large scale of WSIs and various sizes of the abnormal area, how to select informative regions and analyze them are quite…

计算机视觉与模式识别 · 计算机科学 2020-10-14 Shujun Wang , Yaxi Zhu , Lequan Yu , Hao Chen , Huangjing Lin , Xiangbo Wan , Xinjuan Fan , Pheng-Ann Hen

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

计算机视觉与模式识别 · 计算机科学 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Histopathology slides are routinely marked by pathologists using permanent ink markers that should not be removed as they form part of the medical record. Often tumour regions are marked up for the purpose of highlighting features or other…

计算机视觉与模式识别 · 计算机科学 2019-05-14 Sharib Ali , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

图像与视频处理 · 电气工程与系统科学 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Mammalian tissue architecture is central to biological function, and its disruption is a hallmark of disease. Medical imaging techniques can generate large point cloud datasets that capture changes in the cellular composition of such…

Learned Image Compression (LIC) has achieved dramatic progress regarding objective and subjective metrics. MSE-based models aim to improve objective metrics while generative models are leveraged to improve visual quality measured by…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Jixiang Luo , Yan Wang , Hongwei Qin

Pathology is essential for cancer diagnosis, with multiple instance learning (MIL) widely used for whole slide image (WSI) analysis. WSIs exhibit a natural hierarchy -- patches, regions, and slides -- with distinct semantic associations.…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Peixiang Huang , Yanyan Huang , Weiqin Zhao , Junjun He , Lequan Yu

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

图像与视频处理 · 电气工程与系统科学 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

Continual learning is rapidly emerging as a key focus in computer vision, aiming to develop AI systems capable of continuous improvement, thereby enhancing their value and practicality in diverse real-world applications. In healthcare,…

Despite their prominent performance on tasks such as ROI classification and segmentation, many pathology foundation models remain constrained by a specific input size e.g. 224 x 224, creating substantial inefficiencies when applied to…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Mengxuan Hu , Zihan Guan , John Kang , Sheng Li , Zhongliang Zhou

This paper describes a new spatial correspondence representation based on paired regions-of-interest (ROIs), for medical image registration. The distinct properties of the proposed ROI-based correspondence are discussed, in the context of…

计算机视觉与模式识别 · 计算机科学 2024-10-21 Shiqi Huang , Tingfa Xu , Ziyi Shen , Shaheer Ullah Saeed , Wen Yan , Dean Barratt , Yipeng Hu

Survival prediction based on whole slide images (WSIs) is a challenging task for patient-level multiple instance learning (MIL). Due to the vast amount of data for a patient (one or multiple gigapixels WSIs) and the irregularly shaped…

计算机视觉与模式识别 · 计算机科学 2023-07-03 Zhuchen Shao , Yang Chen , Hao Bian , Jian Zhang , Guojun Liu , Yongbing Zhang

Breast cancer diagnosis demands rapid and precise tools, yet traditional histopathological methods often fall short in intra-operative settings. Deep Ultraviolet (DUV) fluorescence imaging emerges as a transformative approach, offering…

计算机视觉与模式识别 · 计算机科学 2026-04-21 Nagur Shareef Shaik , Teja Krishna Cherukuri , Dong Hye Ye

Interpretability is essential in Whole Slide Image (WSI) analysis for computational pathology, where understanding model predictions helps build trust in AI-assisted diagnostics. While Integrated Gradients (IG) and related attribution…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Anh Mai Vu , Tuan L. Vo , Ngoc Lam Quang Bui , Nam Nguyen Le Binh , Akash Awasthi , Huy Quoc Vo , Thanh-Huy Nguyen , Zhu Han , Chandra Mohan , Hien Van Nguyen

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh