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Precise and scalable instance segmentation of cell nuclei is essential for computational pathology, yet gigapixel Whole-Slide Images pose major computational challenges. Existing approaches rely on patch-based processing and costly…

计算机视觉与模式识别 · 计算机科学 2026-01-07 Matěj Pekár , Vít Musil , Rudolf Nenutil , Petr Holub , Tomáš Brázdil

The quantitative detection, segmentation, and characterization of glomeruli from high-resolution whole slide imaging (WSI) play essential roles in the computer-assisted diagnosis and scientific research in digital renal pathology.…

计算机视觉与模式识别 · 计算机科学 2022-06-02 Tianyuan Yao , Yuzhe Lu , Jun Long , Aadarsh Jha , Zheyu Zhu , Zuhayr Asad , Haichun Yang , Agnes B. Fogo , Yuankai Huo

Image registration between histology and magnetic resonance imaging (MRI) is a challenging task due to differences in structural content and contrast. Too thick and wide specimens cannot be processed all at once and must be cut into smaller…

计算机视觉与模式识别 · 计算机科学 2017-08-29 Jonas Pichat , Juan Eugenio Iglesias , Sotiris Nousias , Tarek Yousry , Sebastien Ourselin , Marc Modat

Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Pingyi Chen , Honglin Li , Chenglu Zhu , Sunyi Zheng , Zhongyi Shui , Lin Yang

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

计算机视觉与模式识别 · 计算机科学 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Digital pathology is a tool of rapidly evolving importance within the discipline of pathology. Whole slide imaging promises numerous advantages; however, adoption is limited by challenges in ease of use and speed of high-quality image…

图形学 · 计算机科学 2025-04-24 Ryan Erik Landvater , Ulysses Balis

Segmenting histology images into diagnostically relevant regions is imperative to support timely and reliable decisions by pathologists. To this end, computer-aided techniques have been proposed to delineate relevant regions in scanned…

Humans do not perceive all parts of a scene with the same resolution, but rather focus on few regions of interest (ROIs). Traditional Object-Based codecs take advantage of this biological intuition, and are capable of non-uniform allocation…

图像与视频处理 · 电气工程与系统科学 2022-11-03 Yura Perugachi-Diaz , Guillaume Sautière , Davide Abati , Yang Yang , Amirhossein Habibian , Taco S Cohen

Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing between benign and malignant thyroid tumors is crucial for developing effective treatment plans in clinical practice. Pathologically, thyroid tumors pose…

图像与视频处理 · 电气工程与系统科学 2024-01-04 Jia Dong , Yao Yao , Yang Dong , Hui Ma

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

计算机视觉与模式识别 · 计算机科学 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

Existing WSI analysis methods lie on the consensus that histopathological characteristics of tumors are significant guidance for cancer diagnostics. Particularly, as the evolution of cancers is a continuous process, the correlations and…

计算机视觉与模式识别 · 计算机科学 2024-07-22 Tong Shu , Jun Shi , Dongdong Sun , Zhiguo Jiang , Yushan Zheng

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

图像与视频处理 · 电气工程与系统科学 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Images with abnormal brain anatomy produce problems for automatic segmentation techniques, and as a result poor ROI detection affects both quantitative measurements and visual assessment of perfusion data. This paper presents a new approach…

图像与视频处理 · 电气工程与系统科学 2019-02-19 Svitlana M Alkhimova

With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…

计算机视觉与模式识别 · 计算机科学 2021-02-23 Chen Li , Xintong Li , Md Rahaman , Xiaoyan Li , Hongzan Sun , Hong Zhang , Yong Zhang , Xiaoqi Li , Jian Wu , Yudong Yao , Marcin Grzegorzek

Deep Learning-based computational pathology algorithms have demonstrated profound ability to excel in a wide array of tasks that range from characterization of well known morphological phenotypes to predicting non-human-identifiable…

图像与视频处理 · 电气工程与系统科学 2020-09-24 Ming Y. Lu , Dehan Kong , Jana Lipkova , Richard J. Chen , Rajendra Singh , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Prostate cancer is one of the most frequently diagnosed malignancies in men worldwide. However, precise prediction of biochemical recurrence (BCR) after radical prostatectomy remains challenging due to the multifocality of tumors…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Yesung Cho , Dongmyung Shin , Sujeong Hong , Jooyeon Lee , Seongmin Park , Geongyu Lee , Jongbae Park , Hong Koo Ha

Cryo-electron tomography (cryo-ET) enables high resolution, three-dimensional reconstruction of biological structures, including membranes and membrane proteins. Identification of regions of interest (ROIs) is central to scientific imaging,…

计算机视觉与模式识别 · 计算机科学 2026-02-25 Xingyi Cheng , Julien Maufront , Aurélie Di Cicco , Daniël M. Pelt , Manuela Dezi , Daniel Lévy