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Adaptive designs dynamically update treatment probabilities using information accumulated during the experiment. Existing theory for causal inference from adaptive experiments primarily assumes the superpopulation framework with independent…

统计方法学 · 统计学 2026-02-26 Xinran Li , Anqi Zhao

In many life science experiments or medical studies, subjects are repeatedly observed and measurements are collected in factorial designs with multivariate data. The analysis of such multivariate data is typically based on multivariate…

统计方法学 · 统计学 2023-05-24 Lubna Amro , Frank Konietschke , Markus Pauly

We propose a constrained maximum partial likelihood estimator for dimension reduction in integrative (e.g., pan-cancer) survival analysis with high-dimensional covariates. We assume that for each population in the study, the hazard function…

统计方法学 · 统计学 2023-04-27 Aaron J. Molstad , Rohit K. Patra

We develop flexible multi-parameter regression survival models for interval censored survival data arising in longitudinal prospective studies and longitudinal randomised controlled clinical trials. A multi-parameter Weibull regression…

统计方法学 · 统计学 2019-01-29 Defen Peng , Gilbert MacKenzie , Kevin Burke

Compositional data arise in many real-life applications and versatile methods for properly analyzing this type of data in the regression context are needed. When parametric assumptions do not hold or are difficult to verify, non-parametric…

统计方法学 · 统计学 2023-09-07 Michail Tsagris , Abdulaziz Alenazi , Connie Stewart

The permutation test is known as the exact test procedure in statistics. However, often it is not exact in practice and only an approximate method since only a small fraction of every possible permutation is generated. Even for a small…

In recent years, mixture cure models have gained increasing popularity in survival analysis as an alternative to the Cox proportional hazards model, particularly in settings where a subset of patients is considered cured. The proportional…

统计方法学 · 统计学 2025-12-10 Fatih Kızılaslan , Valeria Vitelli

The cause of failure in cohort studies that involve competing risks is frequently incompletely observed. To address this, several methods have been proposed for the semiparametric proportional cause-specific hazards model under a missing at…

统计方法学 · 统计学 2020-02-24 Giorgos Bakoyannis , Ying Zhang , Constantin T. Yiannoutsos

Feature importance methods using unrestricted permutations are flawed due to extrapolation errors; such errors appear in all non-trivial variable importance approaches. We propose three new approaches: conditional model reliance and…

机器学习 · 统计学 2026-04-14 Emanuele Borgonovo , Francesco Cappelli , Xuefei Lu , Elmar Plischke , Cynthia Rudin

Survivorship analysis allows to statistically analyze situations that can be modeled as waiting times to an event. These waiting times are characterized by the cumulative hazard rate, which can be estimated by the Nelson-Aalen estimator or…

统计理论 · 数学 2019-07-04 Niklas Hohmann

When drawing causal inferences about the effects of multiple treatments on clustered survival outcomes using observational data, we need to address implications of the multilevel data structure, multiple treatments, censoring and unmeasured…

统计方法学 · 统计学 2022-02-18 Liangyuan Hu , Jiayi Ji , Ronald D. Ennis , Joseph W. Hogan

We propose a new class of semiparametric regression models of mean residual life for censored outcome data. The models, which enable us to estimate the expected remaining survival time and generalize commonly used mean residual life models,…

统计理论 · 数学 2020-11-10 Ge Zhao , Yanyuan Ma , Huazhen Lin , Yi Li

The proportional hazards assumption in the commonly used Cox model for censored failure time data is often violated in scientific studies. Yang and Prentice (2005) proposed a novel semiparametric two-sample model that includes the…

统计方法学 · 统计学 2012-06-06 Guoqing Diao , Donglin Zeng , Song Yang

The paper deals with asymptotic properties of the adaptive procedure proposed in the author paper (2007) for estimation of unknown nonparametric regression. We prove that this procedure is asymptotically efficient for a quadratic risk. It…

统计理论 · 数学 2008-12-18 Leonid Galtchouk , Serguey Pergamenshchikov

Adaptive experimentation enables efficient estimation of causal effects, but existing methods are not designed for survival data with censoring, where event times are only partially observed (e.g., overall survival in cancer trials but with…

机器学习 · 计算机科学 2026-05-19 Yuxin Wang , Dennis Frauen , Jonas Schweisthal , Maresa Schröder , Emil Javurek , Stefan Feuerriegel

Incorporating information about the target distribution in proposal mechanisms generally produces efficient Markov chain Monte Carlo algorithms (or at least, algorithms that are more efficient than uninformed counterparts). For instance, it…

统计计算 · 统计学 2021-08-27 Philippe Gagnon

This paper presents a unified treatment of Gaussian process models that extends to data from the exponential dispersion family and to survival data. Our specific interest is in the analysis of data sets with predictors that have an a priori…

统计方法学 · 统计学 2011-06-17 Terrance Savitsky , Marina Vannucci , Naijun Sha

Researchers often have datasets measuring features $x_{ij}$ of samples, such as test scores of students. In factor analysis and PCA, these features are thought to be influenced by unobserved factors, such as skills. Can we determine how…

统计理论 · 数学 2019-09-16 Edgar Dobriban

Variable selection in sparse regression models is an important task as applications ranging from biomedical research to econometrics have shown. Especially for higher dimensional regression problems, for which the link function between…

机器学习 · 统计学 2019-12-10 Burim Ramosaj , Markus Pauly

Canonical correlation analysis (CCA) has become a key tool for population neuroimaging, allowing investigation of associations between many imaging and non-imaging measurements. As other variables are often a source of variability not of…

统计方法学 · 统计学 2024-01-09 Anderson M. Winkler , Olivier Renaud , Stephen M. Smith , Thomas E. Nichols